Organic phosphoric acids and derivatives
Alkali Scientific Pyridoxal Hydrochloride, 5 Grams
Pyridoxal Hydrochloride is a vitamin B6 derivative widely used as a cofactor in enzymatic reactions involving amino acid metabolism. It plays an essential role in transamination, decarboxylation, and other biochemical processes that are critical for protein and neurotransmitter synthesis. This compound is commonly used in enzyme assays and metabolic studies to investigate vitamin-dependent reactions. Its hydrochloride salt form enhances stability and solubility in aqueous solutions, making it suitable for laboratory applications. Pyridoxal hydrochloride is frequently used in biochemical research, cell culture studies, and analytical procedures involving enzymatic activity and metabolic pathways.
Medchemexpress LLC Pyridoxal 5'-phosphate monohydrate | 41468-25-1 | 98.0% | 265.16 | 1 G
Pyridoxal 5'-phosphate monohydrate | 41468-25-1 | 98.0% | 265.16 | 1 G
Medchemexpress LLC Pyridoxal Phosphate-d3 | 1354560-58-9 | 98.0% | 250.16 | 500 UG
Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. It is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules as tracers for quantitation.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
- Relevant for research in cancer, neurological, and metabolic diseases.
Medchemexpress LLC Carvedilol phosphate hemihydrate | 610309-89-2 | 99.9% | C24H26N2O4.H3PO4.1/2H2O | 1 G
Carvedilol phosphate hemihydrate is a non-selective β/α-1 blocker and a multiple action antihypertensive agent. It has potential applications in angina and congestive heart failure. This compound also acts as an autophagy inducer and inhibits the NLRP3 inflammasome.
- Non-selective β/α-1 blocker
- Inhibits lipid peroxidation with an IC50 of 5 μM
- Multiple action antihypertensive agent
- Potential applications in angina and congestive heart failure
- Autophagy inducer
- Inhibits NLRP3 inflammasome
- Inhibits superoxide generation by activated human neutrophils in vitro with an IC50 of 28 μM
- Scavenges oxygen free radicals in a cell-free system with an IC50 of 25 μM
Alkali Scientific Pyridoxal 5 Phosphate Monohydrate, 25 Grams
Pyridoxal 5-Phosphate Monohydrate is the active form of vitamin B6, used as an essential cofactor in numerous enzymatic reactions, including those involved in amino acid metabolism, neurotransmitter synthesis, and glycogen metabolism. Available in a 25-gram quantity, it is used in research on enzyme kinetics, metabolic disorders, and neurological diseases. Pyridoxal phosphate is vital for the proper function of enzymes that convert amino acids into other biochemicals essential for energy production and brain function. It is widely used in laboratory research on vitamin B6 deficiency, neurobiology, and metabolic pathways involving amino acids.
Medchemexpress LLC Amdiglurax phosphate | 1270138-41-4 | 99.8% | C22H33N4O5P | 10MG
Amdiglurax phosphate (NSI-189 phosphate) is the phosphate salt of a neurogenic research compound used in preclinical studies to promote neurogenesis and provide neuroprotective effects. Supplied as a high-purity, white to off-white solid, it is intended for laboratory research use only.
- High purity (99.8%) suitable for research applications.
- White to off-white powder form for easy handling and dissolution.
- Validated storage recommendations for long-term stability.
- Documented neurogenic and neuroprotective activity in preclinical studies.
- Available in small quantities for experimental workflows.
Medchemexpress LLC Tilmicosin phosphate | 137330-13-3 | 98.0% | 1 ML
Tilmicosin phosphate (LY-177370 phosphate) is an orally active macrolide antibiotic and calcium channel antagonist. It primarily acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. This product is effective in treating respiratory diseases in livestock such as cattle, sheep, and pigs, and also exhibits immunomodulatory and anti-inflammatory effects.
- Antibacterial agent
- Inhibits bacterial protein synthesis
- Treats respiratory diseases in livestock
- Exhibits immunomodulatory effects
- Provides anti-inflammatory effects
- Active against *Staphylococcus aureus* isolates
- Induces apoptosis in bovine neutrophils
- Inhibits COX-2 and iNOS expression in macrophages
Medchemexpress LLC Amdiglurax phosphate | 1270138-41-4 | 99.8% | 464.49 g·mol⁻¹ | C22H33N4O5P | 5 MG
Amdiglurax phosphate is the phosphate salt of Amdiglurax (NSI-189), a small-molecule research compound reported to promote neurogenesis and synaptic plasticity. It has been investigated for neuroprotective, antidepressant, and procognitive effects and is supplied for laboratory research use.
- Phosphate salt of a neurogenic small molecule.
- Reported to enhance neurogenesis and synaptic plasticity.
- Demonstrated up-regulation of neurogenic factors such as BDNF and SCF.
- Investigated for antidepressant and procognitive effects.
- Provided with high purity suitable for research applications.
- Soluble in DMSO for experimental use.
Medchemexpress LLC Dimemorfan phosphate | 36304-84-4 | 99.9% | 100 MG
Dimemorfan phosphate is a sigma 1 receptor agonist that is utilized as a potent antitussive. It is intended for research use only and is not sold to patients.
- Sigma 1 receptor agonist
- Potent antitussive
- Inhibits fMLP- and PMA-induced ROS production in a concentration-dependent manner.
- Suppresses Mac-1 upregulation in PMA- and fMLP-activated groups.
- Significantly suppresses LPS-induced ROS and NO production, and LPS-induced iNOS protein expression.
- Blocks the degradation of cytosolic Iκ-Bα and nuclear translocation of NF-κB p65, as well as the transcriptional activity of NF-κB.
- Attenuates BAY k-8644-induced convulsive behaviors and increases in c-fos and c-jun protein expression in a dose-dependent manner.
- Suppresses the increase of plasma TNF-α levels and inhibits infiltration of neutrophils and production of oxidative stress induced by LPS in lung and liver.
Medchemexpress LLC Leniolisib (phosphate) | 1354691-97-6 | 99.1% | 548.45 | 50 MG
Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. It has potential for the treatment of immunodeficiency disorders. This product is for research use only and is not sold to patients.
- Potent and selective PI3Kδ inhibitor
- Potential for immunodeficiency disorders treatment
- Suppresses increased pathway activity (phosphorylation of AKT or S6) caused by APDS mutant p110δ in a concentration-dependent manner
Medchemexpress LLC Dimemorfan (phosphate) | 36304-84-4 | 99.9% | 1 ML
Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive. This product is provided with high purity, ensuring reliable results for research applications.
- Acts as a sigma 1 receptor agonist.
- Potent antitussive properties.
- High purity of 99.9%.
Apexbio Technology LLC Fludarabine Phosphate (Fludara)(Synonyms: Fludara, Fludarabine phosphate, Fludarabine monophosphate, 2-Fluoro-ara-AMP), 10mg, CAS: 75607-67-9.
Fludarabine phosphate (CAS 75607-67-9) marketed as Fludara is a fluorinated nucleotide analog derived from vidarabine (ara-A) exhibiting antineoplastic activities by interfering with DNA synthesis Following rapid extracellular dephosphorylation to 2-fluoro-ara-A this metabolite is intracellularly phosphorylated by deoxycytidine kinase generating the active triphosphate metabolite 2-fluoro-ara-ATP The active metabolite inhibits critical enzymes including DNA polymerase alpha ribonucleotide reductase and DNA primase thereby disrupting DNA replication and ultimately impeding tumor cell proliferation This compound is broadly utilized in biomedical research focused on anticancer mechanisms and nucleotide metabolism studies
Medchemexpress LLC Di-o-cresyl phosphate | 35787-74-7 | >98.0% | 278.24 g·mol⁻¹ | C14H15O4P | 50 MG
Di-o-cresyl phosphate is an organophosphate compound used as a flame retardant and a research reagent in analytical and experimental chemistry. It is identified by CAS 35787-74-7, has molecular formula C14H15O4P and molecular weight 278.24 g·mol⁻¹. Refer to the Certificate of Analysis or SDS for storage, handling, and safety information.
- Used as a flame retardant and biochemical reagent.
- High purity (>98%) suitable for research applications.
- Available in small, weighed quantities for laboratory use.
- Well-defined chemical identifiers for unambiguous reference.
- Store and handle according to the Certificate of Analysis to maintain stability.
Medchemexpress LLC Chlorotris(triphenylphosphine)copper | 15709-76-9 | MFCD00010270 | 98.0% | 885.86 g/mol | C54H45ClCuP3 | 1 G
Chlorotris(triphenylphosphine)copper (CuCl(TPP)3) is a copper(I) coordination complex supplied as a high-purity solid for research use. It is used in biochemical and medicinal chemistry studies where metal-ligand interactions and DNA binding are of interest, and has reported antibacterial, antifungal, antitumor, and antioxidant activity.
- High purity (98.0%).
- Molecular weight 885.86 g/mol.
- Chemical formula C54H45ClCuP3.
- Supplied in research pack sizes (1 g, 5 g, 10 g, 25 g).
- Store at room temperature; protect from light.
- Downloadable data sheet, safety data sheet, and certificate of analysis available.
