Organic phosphoric acids and derivatives
Medchemexpress LLC 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | 18550-98-6 | MFCD00224002 | >98.0% | 210.23 g/mol | C13H10N2O | 10 MG
3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one (3PO) is a small-molecule inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) used as a research probe to study glycolysis and cancer cell metabolism. It reduces glycolytic flux and glucose uptake, lowers intracellular fructose-2,6-bisphosphate, lactate, ATP, and NAD+/NADH, and shows cellular activity in the low micromolar range.
- Inhibits PFKFB3 activity with low micromolar potency.
- Attenuates proliferation of multiple cancer cell lines.
- Reduces glucose uptake and glycolytic metabolites.
- Cell-permeable small molecule suitable for cell-based assays.
- Commonly supplied at high purity for research applications.
- Useful for studies of cancer metabolism and autophagy.
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 50mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Medchemexpress LLC Methyl trioctyl ammonium chloride | 5137-55-3 | MFCD00011862 | 98.0% | 404.16 g/mol | C25H54ClN | 500g
Methyl trioctyl ammonium chloride is a quaternary ammonium salt commonly used as a surfactant stabilizer and phase transfer catalyst in various chemical reactions especially in organic synthesis Methyl trioctyl ammonium chloride has unique chemical properties that facilitate the transfer of ions or molecules from one phase to another making it an important ingredient in a variety of industrial processes
Cambridge Isotope Laboratories TRIBUTYL PHOSPHATE (D27, 98-99%), 1 G, 61196-26-7
TRIBUTYL PHOSPHATE (D27, 98-99%), 1 G, 61196-26-7
Medchemexpress LLC 3PO | 18550-98-6 | 99.9% | 210.23 | 5 MG
3PO is an inhibitor of PFKFB3 that attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. It suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH. This product is suitable for cancer research.
- Inhibits PFKFB3
- Attenuates proliferation of various cancer cell lines (IC50s of 1.4-24 μmol/L)
- Suppresses glucose uptake
- Decreases intracellular levels of Fru-2,6-BP, lactate, ATP, NAD+, and NADH
- Inhibits Jurkat cell proliferation by affecting the cell cycle
- Inhibits growth of Lewis lung carcinoma xenografts
- Inhibits tumor growth in MDA-MB231 human breast adenocarcinoma xenografts
- Inhibits tumor growth in HL-60 leukemia xenografts
TARGETMOL CHEMICALS INC E-3PO 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase) inhibitor. purity: 98%
Medchemexpress LLC 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-, (2E)- | 18550-98-6 | 99.0% | 210.23 | 25 MG
3PO is an inhibitor of PFKFB3, used in cancer research. It attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH.
- Inhibits Jurkat cells proliferation by influencing the cell cycle.
- Suppresses glycolytic flux to lactate in Jurkat cells.
- Inhibits cellular proliferation of transformed tumor cell lines.
- Inhibits Jurkat T cells proliferation by G2-M phase cell cycle arrest.
- Decreases lactate secretion, NADH, NAD+, and ATP in Jurkat cells.
- Inhibited solid tumor and hematologic cell lines (Jurkat, K562, HL-60, MDA-MB231, HeLa, Melanoma, and Lewis Lung) with IC50s of 1.4-24 μM/L.
Cambridge Isotope Laboratories Di-n-Hexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Di-n-Hexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC Methyl trioctyl ammonium chloride | 5137-55-3 | MFCD00011862 | 98.0% | 404.16 g/mol | C25H54ClN | 100g
Methyl trioctyl ammonium chloride is a quaternary ammonium salt commonly used as a surfactant stabilizer and phase transfer catalyst in various chemical reactions especially in organic synthesis Methyl trioctyl ammonium chloride has unique chemical properties that facilitate the transfer of ions or molecules from one phase to another making it an important ingredient in a variety of industrial processes
Medchemexpress LLC 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)- | 13309-08-5 | 99.9% | 210.24 | 1 ML
(E/Z)-3PO is a potent PFKFB3 inhibitor available as an off-white to light yellow solid. This compound has a molecular formula of C13H10N2O and a molecular weight of 210.24, with a high purity of 99.9% by LCMS. It is intended for laboratory research use only.
- Potent PFKFB3 inhibitor
- High purity for reliable research
- Off-white to light yellow solid form
- Suitable for various laboratory applications
Medchemexpress LLC Phosphoric acid tributyl ester-d27 | 61196-26-7 | 100.0% | 293.48 | C12D27O4P | 50 MG
Deuterium-labeled tributyl phosphate (Tributyl phosphate-d27) supplied as a 50 mg solid for research use. It is intended as an internal standard and tracer for analytical techniques including NMR, GC-MS, and LC-MS, and is suitable for quantitative and structural studies. Store and handle under recommended conditions to preserve isotopic and chemical integrity.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS
- High isotopic purity for accurate quantitation
- Soluble in DMSO at ≥100 mg/mL for convenient stock preparation
- Suitable for use as a tracer or internal standard in analytical workflows
- Stable as a solid when stored at -20°C under recommended conditions
Medchemexpress LLC 3-fluoro-2-(tributylstannyl)pyridine | 573675-60-2 | 386.14 g/mol | C17H30FNSn | 500 MG
3-fluoro-2-(tributylstannyl)pyridine is an organotin-substituted pyridine provided as a research reagent and synthetic intermediate. It is identified by CAS number 573675-60-2 and has molecular formula C17H30FNSn (molecular weight 386.14 g/mol).
- Organotin-substituted pyridine used as a synthetic building block
- Molecular formula C17H30FNSn
- Molecular weight 386.14 g/mol
- CAS number 573675-60-2
- Available in milligram-scale pack sizes (250 mg, 500 mg, 1 g, 5 g)
- For research use only
Medchemexpress LLC 3-fluoro-2-(tributylstannyl)pyridine | 573675-60-2 | MFCD09265496 | 95.0% | 386.14 | C17H30FNSn | 250 MG
3-Fluoro-2-(tributylstannyl)pyridine is an organotin-substituted pyridine reagent used as an intermediate in organic synthesis and cross-coupling research applications. It is supplied as a colorless to light yellow liquid and is offered in laboratory pack sizes for research use.
- Organotin-substituted pyridine reagent
- Molecular weight 386.14
- Chemical formula C17H30FNSn
- Cas number 573675-60-2
- Colorless to light yellow liquid
- Available in small laboratory pack sizes (e.g., 250 MG)
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES SODIUM DIHYDR PHOSPH MO 1KG
NC3662708 SODIUM DIHYDR PHOSPH MO 1KG