Organic sulfuric acids and derivatives
Apexbio Technology LLC Piriprost (potassium salt) 88851-62-1 5mg
Piriprost (potassium salt CAS 88851-62-1) also known as U 60257 is a small molecule inhibitor of leukotriene biosynthesis Leukotrienes are inflammatory mediators derived from eicosanoid metabolism in leukocytes and act via G protein-coupled receptors By inhibiting 5-lipoxygenase-mediated production of leukotriene B4 sulfidopeptide leukotrienes and the metabolite 5-HETE Piriprost reduces leukotriene-driven inflammatory processes in experimental mast cell and basophil leukemia models exhibiting IC50 values in the 9 50 M range Piriprost has also been investigated for effects on pulmonary permeability endometrial cell alkaline phosphatase activity and alveolar epithelial integrity offering utility in inflammatory and respiratory research
TARGETMOL CHEMICALS INC DEXTRAN SULFATE SODIUM 5000MG
Also available in 500 mg 10000 mg and bulk. Please contact Fisher for quotes. Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) is a commonly used modeling compound for inflammatory bowel disease. It can destroy the integrity of the intestinal mucosal barrier through the high negative charge caused by sulfate groups leading to intestinal barrier damage macrophage dysfunction and bacterial flora disorder. purity: 98%
Medchemexpress LLC p-Cresyl sulfate | 3233-58-7 | 100.0% | 188.20 | 1 ML
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin known to cause renal damage and dysfunction. It exhibits antiproliferation activity and influences the expression of HIF-1α, VHL, and HIF-2α. This compound also induces epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways.
- Shows antiproliferation activity.
- Increases protein expression of HIF-1α and VHL.
- Decreases protein expression of HIF-2α.
- Induces epithelial-mesenchymal transition (EMT).
- Activates JNK and p38 MAPK signaling pathways.
eMolecules TargetMol GC7 Sulfate 25mg 787749244 T11372 0 000 150417-90-6 270 350 C8H22N4O4S
TargetMol GC7 Sulfate 25mg 787749244 T11372 0 000 150417-90-6 270 350 C8H22N4O4S
Medchemexpress LLC Phenelzine sulfate | 156-51-4 | 99.95% | 100 MG
Phenelzine sulfate | 156-51-4 | 99.95% | 100 MG
Medchemexpress LLC Vindesine sulfate | 59917-39-4 | 99.4% | 50 MG
Vindesine sulfate is a potent tubulin inhibitor that exhibits anti-proliferation effects in vitro and antitumor effects in vivo. For example, it inhibits L-cells growth, showing approximately 25% inhibition at 40 nM.
- Potent tubulin inhibitor with a Ki of 0.110 μM
- Exhibits anti-proliferation effects in vitro
- Exhibits antitumor effects in vivo
- Inhibits L-cells growth, showing approximately 25% inhibition at 40 nM
Medchemexpress LLC Atropine sulfate monohydrate | 5908-99-6 | 99.9% | 50 MG
Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. With IC50 values of 0.39 nM for Human mAChR M4 and 0.71 nM for Chicken mAChR M4, it inhibits ACh-induced relaxations in human pulmonary veins. This compound can be used for research related to anti-myopia and bradycardia.
- Acts as a competitive muscarinic acetylcholine receptor (mAChR) antagonist.
- Inhibits ACh-induced relaxations in human pulmonary veins.
- Suitable for research on anti-myopia and bradycardia.
Medchemexpress LLC Vindesine sulfate | 59917-39-4 | 99.17% | 100 MG
Vindesine sulfate is a potent tubulin inhibitor with a Ki of 0.110 μM. It exhibits anti-proliferation effects in vitro and antitumor effects in vivo. It is a white to off-white solid.
- Potent tubulin inhibitor
- Anti-proliferation effects in vitro
- Antitumor effects in vivo
- Solid appearance
- White to off-white color
- Store at -20°C, sealed, and away from moisture
Medchemexpress LLC Cholesteryl sulfate sodium | 2864-50-8 | 99.86% | 488.70 | 1 ML
Cholesteryl sulfate sodium | 2864-50-8 | 99.86% | 488.70 | 1 ML
Medchemexpress LLC Axelopran sulfate | 949904-50-1 | 555.68 g/mol | C26H41N3O8S | 10 MG
Axelopran sulfate is the sulfate salt of axelopran, an opioid receptor antagonist used in research to profile μ, δ, and κ opioid receptors. It is supplied for laboratory research, is highly soluble in DMSO, and has reported pKi values of 9.8 (human μ), 8.8 (human δ), and 9.9 (guinea pig κ).
- Sulfate salt form suitable for laboratory research.
- High reported affinity for opioid receptors (pKi 9.8-9.9).
- Soluble in DMSO: ≥ 100 mg/mL.
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Intended for in vitro and preclinical opioid receptor pharmacology studies.
Medchemexpress LLC Ceftolozane sulfate | 936111-69-2 | 99.7% | 764.77 | 5 MG
Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. It binds to P. aeruginosa essential PBPs (1b, 1c, 2 and 3) with high affinity and inhibits cell wall synthesis. Ceftolozane sulfate inhibits P. aeruginosa and Enterobacteriaceae.
- Antibacterial activity against fully AmpC-derepressed P. aeruginosa
- Antipseudomonal activity against carbapenem-resistant and MDR isolates
- Reduces ESBL-producing Enterobacteriaceae in neutropenic mice
- Reduces bacterial load and improves early pulmonary inflammatory response in a mice model of Pseudomonas aeruginosa acute pneumonia
Medchemexpress LLC NVP-CGM097 sulfate | 1313367-56-4 | MFCD31382179 | 98.8% | 757.34 g/mol | C38H49ClN4O8S | 10 MG
NVP-CGM097 sulfate is a potent, selective small-molecule inhibitor of MDM2 supplied as the sulfate salt for research applications. It binds human MDM2 with high potency (IC50 1.7 ± 0.1 nM) and is provided at high reported purity for biochemical and cellular studies.
- Potent MDM2 inhibitor with IC50 1.7 ± 0.1 nM for hMDM2.
- Provided as the sulfate salt.
- Reported purity of 98.82%.
- Molecular weight 757.34 g/mol and formula C38H49ClN4O8S.
- Available in small-scale quantities suitable for laboratory research.
Medchemexpress LLC Vindesine sulfate | 59917-39-4 | 99.40% | 10 MG
Vindesine sulfate is a potent tubulin inhibitor with a Ki of 0.110 μM. It demonstrates an anti-proliferation effect in vitro and an antitumor effect in vivo. In vitro, Vindesine sulfate inhibits L-cells growth, showing approximately 25% inhibition at 40 nM.
- Potent tubulin inhibitor
- Ki of 0.110 μM
- Demonstrates anti-proliferation effect in vitro
- Shows antitumor effect in vivo
- Inhibits L-cells growth (approx. 25% inhibition at 40 nM)