Organic sulfuric acids and derivatives
Medchemexpress LLC p-Cresyl sulfate potassium | 91978-69-7 | 99.9% | 226.29 | 50 MG
p-Cresyl sulfate potassium (Standard) is an analytical standard used in research and analytical applications. It is a uremic toxin linked to renal damage and dysfunction. This compound exhibits antiproliferation activity, influences protein expression (HIF-1α, VHL, HIF-2α), and activates JNK and p38 MAPK signaling pathways. It is suitable for experiments involving HPLC, GC, and MS.
- Analytical standard for research.
- Uremic toxin causing renal damage and dysfunction.
- Exhibits antiproliferation activity.
- Modulates protein expression (HIF-1α, VHL, HIF-2α).
- Induces epithelial-mesenchymal transition (EMT).
- Activates JNK and p38 MAPK signaling pathways.
- Applicable in HPLC, GC, and MS research.
Medchemexpress LLC BM 15766 sulfate | 86621-94-5 | 98.2% | 482.98 | 25 MG
BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase, which works to reduce plasma cholesterol levels. It functions as a hypolipidemic agent.
- Inhibitor of 7-dehydrocholesterol δ7-reductase
- Reduces plasma cholesterol levels
- Acts as a hypolipidemic agent
- Inhibits 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in HL60 cells with an IC50 of 500 nM
Medchemexpress LLC Dextran sulfate low 5g | 9011-18-1 | ca 40,000 Da | 5 G
Dextran sulfate (sodium salt) is a sulfated polysaccharide with an average molecular weight of approximately 40,000 Da (CAS 9011-18-1). Supplied as a dry powder for research use, it is used as a cell culture additive, a reagent in inflammation models, and as a biochemical inhibitor in coagulation and antiviral assays.
- Average molecular weight around 40,000 Da.
- Powder form for dissolution in aqueous buffers.
- Reduces cell aggregation when used as a culture additive.
- Used to induce colitis in animal models for inflammation studies.
- Functions as an inhibitor of complement and coagulation pathways in assays.
Medchemexpress LLC Galegine hemisulfate | 14279-86-8 | 176.23 | 5 MG
Galegine hemisulfate is a guanidine derivative that contributes to weight loss in mice. It activates AMPK in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma cells, and HEK293 human kidney cell lines. It also exhibits antibacterial activity with a minimum inhibitory concentration of 4 mg/L against *Staphylococcus aureus* strains.
- Contributes to weight loss in mice
- Activates AMPK in various cell lines (3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma, HEK293 human kidney cells)
- Has antibacterial activity against *Staphylococcus aureus* strains
- Stimulates insulin-independent glucose uptake by 3T3-L1 adipocytes and L6 myotubes in a concentration-dependent manner
- Reduces basal glycerol release and markedly reduces Isoprenaline-stimulated glycerol release from 3T3-L1 adipocytes
Medchemexpress LLC Vinblastine (sulfate) | 143-67-9 | 99.86% | 909.05 | 100 MG
Vinblastine sulfate is a cytotoxic alkaloid that targets various cancer types by inhibiting microtubule formation and suppressing nAChR (IC50 8.9 μM). It blocks mitosis (IC50 0.8 nM in HeLa cells), leading to cell apoptosis. For storage, keep sealed at 4°C, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month, similarly sealed. Room temperature shipping is suitable for durations under 2 weeks.
- Inhibits microtubule formation.
- Suppresses nAChR with an IC50 of 8.9 μM.
- Blocks mitosis, leading to cell apoptosis.
- Induces apoptosis via Bax/Bcl-2 imbalance.
- Suppresses NFκB expression and depresses NFκB-DNA binding activity.
- Triggers apoptosis by causing a loss of mitochondrial membrane potential and activating caspases.
Medchemexpress LLC Sitosterol sulfate (trimethylamine) | 521.37 | 50 MG
Sitosterol sulfate (trimethylamine) is categorized as an active compound. It finds utility in various biological research applications.
- Active compound
- Suitable for biological research
Medchemexpress LLC Colistin, sulfate (salt) | 1264-72-8 | >98.0% | C52H98N16O13.2.5H2O4S | 1 ML
Colistin sulfate is a polypeptide antibiotic that inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in their outer cell membrane. It is intended for research use only.
- Polypeptide antibiotic
- Inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in their outer cell membrane, and by electrostatically interfering with the outer membrane by competitively displacing divalent cations from the negatively charged phosphate groups of membrane lipids
- Bactericidal to gram-negative bacteria with a narrow spectrum of activity
- Associated with slow development of resistance for treating infections caused by multidrug-resistant gram-negative bacteria
- Available as colistin (sulfate) mainly for topical use, and colistin methanesulfonate (sodium) for parenteral use
Medchemexpress LLC p-Cresyl sulfate | 3233-58-7 | 99.98% | 188.20 | 25 MG
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin that can cause renal damage and dysfunction. It demonstrates antiproliferation activity, increases the protein expression of HIF-1α and VHL, and decreases the protein expression of HIF-2α. Additionally, p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways.
- Is a uremic toxin.
- Can cause renal damage and dysfunction.
- Shows antiproliferation activity.
- Increases the protein expression of HIF-1α and VHL.
- Decreases the protein expression of HIF-2α.
- Induces epithelial-mesenchymal transition (EMT).
- Activates the JNK and p38 MAPK signaling pathways.
- Inhibits lipogenesis and increases lipolysis in adipocytes in 3T3-L1 cells.
- Induces osteoblast dysfunction through activating JNK and p38 MAPK pathways.
- Induces ROS production in primary osteoblastic cells.
Medchemexpress LLC Keratin sulfate | 169799-44-4 | 84.2% | 500 MG
Keratin sulfate is a heparin-related proteoglycan that interacts with the receptor or alters its stability and function. It does not enhance the mitogenic effect of FGF-2.
- Heparin-related proteoglycan
- Interacts with receptors or alters their stability and function
- Does not enhance the mitogenic effect of FGF-2
- Solid appearance
- Off-white to light yellow color
- Solubility in H2O: 40 mg/mL (needs ultrasonic)
- For research use only
Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | 99.6% | 578.61 | 5 MG
Lobeglitazone sulfate is a novel thiazolidinedione, functioning as an orally active agonist for PPAR with EC50 values of 137.4 nM for PPARγ and 546.3 nM for PPARα. It acts as an inhibitor for the ERK/JNK/Smad/NF-κB signaling pathway, demonstrating anti-inflammatory, anti-diabetic, anti-fibrotic, and anti-atherosclerotic properties.
- Functions as an orally active agonist for PPAR
- Inhibits ERK/JNK/Smad/NF-κB signaling pathway
- Exhibits anti-inflammatory properties
- Exhibits anti-diabetic properties
- Exhibits anti-fibrotic properties
- Exhibits anti-atherosclerotic properties
- Increases glucose uptake in 3T3-L1 adipocytes and L6 muscle cells
- Inhibits NO generation and pro-inflammatory cytokine expression
Medchemexpress LLC Dextran sulfate sodi 5g | 9011-18-1 | 16,000-24,000 Da | 5 G
Dextran sulfate sodium salt (MW 16,000-24,000 Da) is a sulfated polysaccharide supplied as a dry powder for use as a biochemical reagent in assays and inflammation research. It is water soluble with sonication and should be stored refrigerated or frozen depending on storage duration.
- Powder form for easy handling and weighing.
- Molecular weight range 16,000-24,000 Da for consistent biological activity.
- Soluble in water with sonication for stock preparation.
- Available in convenient small-scale packaging for lab use.
- Stable under refrigerated or frozen storage per datasheet.
Medchemexpress LLC Iobenguane (sulfate) | 87862-25-7 | 25 MG
Iobenguane sulfate is an analytical standard intended for research and analytical applications. This compound, an analogue of the neurotransmitter norepinephrine, exhibits antitumor activity. Radioiodinated iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical for the diagnosis and treatment of adrenergic tumors. It also serves as a high-affinity substrate for cholera toxin, interfering with cellular mono(ADP-ribosylation).
- Used as an analytical standard
- Intended for research and analytical applications
- Analog of norepinephrine with antitumor activity
- Radioiodinated form used as a tumor-targeted radiopharmaceutical
- High-affinity substrate for cholera toxin
- Commonly used in HPLC, GC, and MS experiments
Medchemexpress LLC Dextran sulfate low 1g | 9011-18-1 | 40,000 Da | (C6H9NaO8S)n | 1 G
Dextran sulfate, low sulfate (average MW 40,000) is a sulfated polysaccharide provided as the sodium salt for biochemical and cell-assay use. It is used experimentally as an anticoagulant and as a reagent with reported antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing activities.
- Sulfated polysaccharide with average molecular weight ~40,000 Da.
- Provided as the sodium salt, water-soluble powder.
- Commonly used in biochemical and cell-based assays.
- Reported activities: anticoagulant, antiviral, antibacterial, anti-inflammatory, antifibrotic, wound-healing.
- Typically packaged in small research quantities; 1 G pack sizes are available.
Medchemexpress LLC Phenyl hydrogen sulfate | 937-34-8 | 99.5% | 100 MG
Phenyl sulfate is an orally active, gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in experimental models of diabetes and can be used as a disease marker in diabetic kidney disease. It appears as a white to off-white solid.
- Orally active gut microbiota-derived metabolite
- Induces albuminuria and podocyte damage in experimental models of diabetes
- Used as a disease marker in diabetic kidney disease
- Appears as a white to off-white solid
- High purity of 99.47%
- Soluble in water
Medchemexpress LLC Cefpirome sulfate | 98753-19-6 | MFCD08234364 | 99.0% | 612.66 g/mol | C22H24N6O9S3 | 10 MG
Cefpirome sulfate is an analytical reference material of cefpirome, a fourth-generation cephalosporin antibiotic. The substance is supplied as a light yellow to yellow solid with identity confirmed by 1H NMR and mass spectrometry, and accompanied by a certificate of analysis reporting HPLC purity and assay results. Stored sealed and dry at 4°C, it is intended for research and analytical applications.