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Organic compounds that contain one or more hydroxyl groups indirectly attached to a carbonyl group via an intervening vinyl functional group (-C=C-; also known as carbon - carbon double bond).
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IACS-8803 disodium is a cyclic dinucleotide stimulator of interferon genes (STING) agonist described by investigators at the Institute for Applied Cancer Science (MD Anderson). Supplied as the disodium salt for research use, it shows robust systemic antitumor efficacy in preclinical studies and includes documented solubility and formulation guidance for in vitro and in vivo experiments.
Potent activation of the STING pathway demonstrated in preclinical studies.
Water-soluble disodium salt with documented solubility in DMSO, water, and PBS.
Suggested in vivo formulations and dosing vehicles provided for clear solution preparation.
High chemical purity suitable for laboratory research applications.
Intended for research use only; not for human or clinical use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
IACS-8803 disodium is a potent cyclic dinucleotide STING agonist provided as the disodium salt for preclinical research. It activates STING signaling to stimulate interferon responses and has demonstrated robust systemic antitumor efficacy in mouse models. The compound is a white to off-white solid with high reported purity and is supplied in small solid quantities or as a DMSO solution.
Activates STING pathway in vitro and in vivo.
Demonstrates robust systemic antitumor efficacy in preclinical models.
High purity suitable for research applications.
Soluble in DMSO and moderately soluble in water; vehicle protocols available for in vivo use.
Store under nitrogen, away from moisture; follow cold storage recommendations.
Available in small-mass solid quantities and as a prepared solution for convenience.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
FTISADTSK acetate is an endogenous stable signature peptide derived from Trastuzumab. It is specifically monitored by selected reaction monitoring (SRM) and is intended solely for research applications.
Endogenous stable signature peptide
Monitored by selected reaction monitoring (SRM)
Suitable for research use only
Solid appearance, ranging from white to light brown
Molecular weight: 1029.10
Chemical formula: C44H72N10O18
Soluble in water at 50 mg/mL (48.59 mM), may require sonication
Powder storage: -80°C for 2 years or -20°C for 1 year
Solution storage: -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
Ships at room temperature within the continental US
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More