Azepines
Cayman Chemical CarbamazepIn 10g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Medchemexpress LLC N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester | 286961-15-7 | 98.59% | 343.23 | 5 G
N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent. It is intended solely for research purposes and not for sale to patients. This compound is a solid with a white to off-white appearance.
- High purity (98.59%)
- Suitable for biochemical research
- Long-term storage stability as powder and in solvent
- Consistent with structure by 1H NMR and LCMS
Aobchem 2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 500mg
2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 500mg
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | 252.27 | C15H12N2O2 | 10 MG
Oxcarbazepine (Standard) is an analytical reference standard of oxcarbazepine supplied for research and analytical applications. It is intended for qualitative, quantitative, and methodological experiments in HPLC, GC, and MS, and is commonly used for method development and assay calibration. CAS 28721-07-5.
- Analytical reference standard for HPLC, GC, and MS.
- High purity (99.88%), suitable for quantitative analysis.
- Available in multiple small package sizes, including 10 mg.
- Supplied with certificate of analysis and safety data sheet.
- Intended for method development, assay calibration, and quality control.
Aobchem 2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 250mg
2 2-Difluoro-1-(5 6 7 8-tetrahydro-2-naphthalenyl)-1-propanone | 95% | CAS 1871596-76-7 | C13H14F2O | 250mg
Aobchem 2 2-Difluoro-1-(5 6 7 8-tetrahydro-5 5 8 8-tetramethyl-2-naphthalenyl)ethanone | 95% | CAS 177361-22-7 | C16H20F2O | 1g
2 2-Difluoro-1-(5 6 7 8-tetrahydro-5 5 8 8-tetramethyl-2-naphthalenyl)ethanone | 95% | CAS 177361-22-7 | C16H20F2O | 1g
Aobchem 4-(2-Chlorothiazol-5-yl)tetrahydro-2H-pyran-4-ol | 95% | CAS 161802-22-8 | C8H10ClNO2S | 250mg
4-(2-Chlorothiazol-5-yl)tetrahydro-2H-pyran-4-ol | 95% | CAS 161802-22-8 | C8H10ClNO2S | 250mg
Sigma Aldrich Fine Chemicals Biosciences Carbamazepine powder5G
CARBAMAZEPINE4 Carbamazepine powder5G
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 1 ML
Oxcarbazepine (GP 47680) is an anti-epileptic agent that functions as a sodium channel blocker. It significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits both anti-cancer and anticonvulsant effects.
- Inhibits glioblastoma cell growth with IC50 values of 12.35 μg/mL for U87 cell lines and 9.45 μg/mL for T98 cell lines.
- Protects mice and rats against generalized tonic-clonic seizures induced by electroshock.
- No tolerance to anticonvulsant effect observed in rats treated daily for 4 weeks.
- Functions as a sodium channel blocker.
- Induces apoptosis or G2/M arrest in glioblastoma cell lines.
Sigma Aldrich Fine Chemicals Biosciences Epinastine hydrochloride European Pharmacopoeia (EP) Reference Standard | 108929-04-0 | MFCD00933434 |
Epinastine hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 285.77 | 108929-04-0 | MFCD00933434 |