Azetidines
Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 25 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline, found in common beets. It can be misincorporated into proteins in place of proline in many species, including humans, and is considered a toxic and teratogenic agent. This compound is intended for research use only.
- Non-proteinogenic amino acid homologue of proline
- Found in common beets
- White to off-white solid appearance
- For research use only
- Store solid at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in water (50 mg/mL)
Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 1 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline, found in common beets. It can be misincorporated into proteins in place of proline in many species, including humans, acting as a toxic and teratogenic agent. Studies show it incorporates into collagen synthesized by chick embryo cartilage in vitro.
- Appearance: Solid
- Color: White to off-white
- Structure classification: Amino acids
- Initial source: Plants (Beta vulgaris Linn.)
- Solubility: 50 mg/mL in water (requires ultrasonic)
- Solid storage: 4°C, sealed, away from moisture
- Solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC L-azetidine-2-carboxylic acid | 2133-34-8 | 99.9% | 101.10 g/mol | C4H7NO2 | 1 ML
L-azetidine-2-carboxylic acid is a proline analog research reagent used to study protein folding, endoplasmic reticulum (ER) stress, autophagy, and apoptosis pathways. It is supplied as a solid and as a 10 mM solution in water and has reported high chemical purity.
- Proline analog that perturbs protein synthesis and folding
- Induces ER stress and protein misfolding
- Upregulates LC3-II via PERK activation (autophagy marker)
- Increases pro-apoptotic BAX and induces ATF6 cleavage
- Available as solid and as a 10 mM, 1 mL aqueous solution
- High purity, reported at 99.85%
- CAS number 2133-34-8; formula C4H7NO2; molecular weight 101.10 g/mol
Medchemexpress LLC L-azetidine-2-carboxylic acid | 2133-34-8 | MFCD00005166 | 99.9% | 101.10 g/mol | C4H7NO2 | 1 G
L-azetidine-2-carboxylic acid is a non-proteinogenic amino acid and a proline analog used in biochemical and cell biology research to induce endoplasmic reticulum (ER) stress, protein misfolding, and related cellular pathways. It is provided as a solid for laboratory use and includes documentation such as COA and SDS.
- Non-proteinogenic amino acid proline analog.
- CAS number 2133-34-8.
- Molecular formula C4H7NO2.
- Molecular weight 101.10 g/mol.
- Purity 99.9%.
- Appearance solid, white to off-white.
- Soluble in water (100 mg/mL with ultrasonic assistance); sparingly soluble in DMSO.
- Storage 4°C, protect from light; in solution -80°C (6 months) or -20°C (1 month).
- Available pack sizes include 1 G.