Azetidines
Medchemexpress LLC L-Azetidine-2-carboxylic acid | 2133-34-8 | 99.9% | 101.10 | 500 MG
L-Azetidine-2-carboxylic acid is a proline analog that influences cellular processes such as lipid autophagy and endoplasmic reticulum stress. It is known to upregulate the lipid autophagy marker LC3-II and increase pro-apoptotic BAX protein, while also inducing ATF6 cleavage and upregulating phosphorylated eIF2α levels. This compound induces ER stress, leading to protein misfolding and aggregation, and has demonstrated teratogenic, pro-inflammatory, and pro-apoptotic effects.
- Upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway.
- Increases pro-apoptotic BAX protein.
- Induces ATF6 cleavage and upregulates phosphorylated eIF2α levels.
- Induces ER stress, leading to protein misfolding and aggregation.
- Shows teratogenic, pro-inflammatory, and pro-apoptotic effects.
Research Products International Corp Ceftazidime Hydrate, 25 G
Ceftazidime is a third-generation cephalosporin antibiotic used in research settings. It is effective against a broad spectrum of bacteria, including Gram-negative and some Gram-positive bacteria.
Ceftazidime works by inhibiting bacterial cell wall synthesis, ultimately leading to the death of susceptible bacteria. It may be utilized as a selective agent in microbiology and molecular biology experiments.
Incorporate ceftazidime into culture media to selectively promote the growth of bacterial strains that carry resistance genes against this antibiotic. This is often achieved by introducing a plasmid or vector containing a ceftazidime resistance gene into the bacteria of interest.
Medchemexpress LLC 1-Boc-D-azetidine-2-carboxylic acid | 228857-58-7 | MFCD01320888 | 99.0% | 201.22 g/mol | C9H15NO4 | 5 G
1-Boc-D-azetidine-2-carboxylic acid is a Boc-protected D-azetidine amino acid derivative used as a synthetic intermediate in medicinal chemistry and organic synthesis. The N-Boc protection facilitates selective amine protection and subsequent coupling or derivatization of the azetidine ring, enabling preparation of azetidine-containing active compounds and building blocks.
- Boc-protected azetidine scaffold for versatile synthetic transformations.
- High purity (≈99.0%).
- Molecular weight 201.22 g/mol; formula C9H15NO4.
- Available in multiple small-scale pack sizes for laboratory synthesis.
- Stable as a solid at room temperature for up to 3 years; in solvent, long-term storage at -80°C.
- Suitable as a building block for medicinal chemistry and lead optimization.