Azobenzenes
Medchemexpress LLC D5D-IN-326 | 1236767-85-3 | 99.9% | 473.27 | C17H11F8N3O4 | 10 MG
D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor used in preclinical research. It demonstrates low-nanomolar potency in enzymatic and cell-based assays and has been reported to improve metabolic parameters in diet-induced obese mice. Documentation typically includes a product datasheet, certificate of analysis, and safety data sheet.
- Selective delta-5 desaturase inhibition with low-nanomolar potency.
- Demonstrated activity in enzymatic and cell-based assays.
- Reduces insulin resistance and body weight in preclinical mouse models.
- High purity (99.9% by LC-MS) confirmed by certificate of analysis.
- Supplied as a small-molecule research reagent with supporting documentation for reproducibility.
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 25 MG
C-021 is a small-molecule CCR4 antagonist supplied for research use. It inhibits CCR4-mediated chemotaxis in human and mouse cells and blocks CCL22-induced GTPγS binding, making it suitable for biochemical and cellular assays.
- Target: CCR4 (GPCR), suitable for immunology and GPCR research.
- Potent CCR4 antagonist with reported IC50s of 140 nM (human chemotaxis), 39 nM (mouse chemotaxis), and 18 nM in GTPγS binding assays.
- Molecular formula C27H41N5O2 and molecular weight 467.65 g/mol.
- Reported purity 99.95% and solid appearance (off-white to light yellow).
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or animal therapeutic use.
Medchemexpress LLC 2-(2,2,3,3,3-pentafluoropropoxy)-3-(4-(2,2,2-trifluoroethoxy)phenyl)-5,7-dihydropyrrolopyrimidine-4,6-dione | 1236767-85-3 | 99.9% | 473.27 | C17H11F8N3O4 | 100 MG
D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor supplied as a powder for research use. It shows low-nanomolar potency (IC50 22 nM human, 72 nM rat), has molecular weight 473.27, and is reported at high purity (99.9%). Preclinical studies indicate improved insulin sensitivity and weight reduction in diet-induced obese mice. Store and handle per the manufacturer's recommendations.
- Selective delta-5 desaturase inhibitor with low-nanomolar potency.
- High purity suitable for pharmacology studies (99.9%).
- Powder form, convenient for formulation and dosing.
- Suitable for in vitro and in vivo pharmacology studies.
- Certificate of analysis and safety data sheet available.
- Defined storage conditions for powder and solutions to preserve stability.
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eMolecules 70415-85-9 | ISOPROPYL(2-NITROPHENYL)SULFANE | AstaTech | MFCD13689000 | 197.250 | C9H11NO2S | 95.000 | CC(C)Sc1ccccc1[N+]([O-])=O | 0.25g | 434269003
ISOPROPYL(2-NITROPHENYL)SULFANE | AstaTech | 70415-85-9 | MFCD13689000 | 197.250 | C9H11NO2S | 95.000 | CC(C)Sc1ccccc1[N+]([O-])=O | 0.25g | 434269003
Medchemexpress LLC HKOCl-4 (BXY2142) | 2031170-85-9 | 95.1% | 1 MG
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe designed for the detection of hypochlorous acid, offering excellent sensitivity and selectivity. It possesses a longer absorption wavelength and improved pH stability compared to fluorescein-based probes. This probe is intended for research use only.
- Detection of hypochlorous acid
- Excellent sensitivity and selectivity
- Longer absorption wavelength
- Improved pH stability
- Excitation wavelength: 530 nm
- Emission wavelength: 557 nm
- Ultra-fast response to HOCl (reaches plateau within 2 min)
- More than 20-fold increase in fluorescence intensity over other analytes
- Non-toxic in living cells at concentrations up to 50 μM in RAW264.7 macrophages
eMolecules 947669-86-5 | Medchem Express | WWL113 | 5mg | 713704307 | HY-110148 | MFCD28160857 | 466.537 | C29H26N2O4
Medchem Express | WWL113 | 5mg | 713704307 | HY-110148 | 947669-86-5 | MFCD28160857 | 466.537 | C29H26N2O4
Medchemexpress LLC Mitoguazone 10mg | 459-86-9 | 10MG
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis Mitoguazone induces cell apoptosis Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages Mitoguazone has the potential for acute leukemia Hodgkin s and non-Hodgkin s lymphoma treatment[1 [2 [3 [4
eMolecules 23410-98-2 | Pyridine-2,3-dicarboxylic acid 2-benzyl ester | J&W PharmLab LLC257.245 | C14H11NO4 | 96.000 | OC(=O)c1cccnc1C(=O)OCc1ccccc1 | 500mg | 722712571
Pyridine-2,3-dicarboxylic acid 2-benzyl ester | J&W PharmLab LLC | 23410-98-2257.245 | C14H11NO4 | 96.000 | OC(=O)c1cccnc1C(=O)OCc1ccccc1 | 500mg | 722712571
eMolecules 648927-86-0 | Medchem Express | Firibastat | 5mg | 599150364 | HY-109058 | MFCD20921962 | 368.5 | C8H20N2O6S4
Medchem Express | Firibastat | 5mg | 599150364 | HY-109058 | 648927-86-0 | MFCD20921962 | 368.500 | C8H20N2O6S4
Medchemexpress LLC ELN318463 | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 5 MG
ELN318463 is a selective γ-secretase inhibitor that targets amyloid precursor protein (APP). It exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase, showing significantly higher selectivity for PS1. This compound behaves as a classic γ-secretase inhibitor and has been shown to reduce brain Aβ levels in models of Alzheimer's disease.
- Highly selective inhibition of PS1 γ-secretase.
- Demonstrates potent inhibition of Aβ production in cells.
- Shows reduced brain Aβ levels in animal models.
- Possesses characteristics of a classic γ-secretase inhibitor.
- Off-white to light yellow solid appearance.
- Soluble in DMSO.
- Available in various quantities.
- Stable under recommended storage conditions.
Medchemexpress LLC BPK-25 | 2305052-86-0 | 99.9% | C21H17ClN4O2 | 50 MG
BPK-25 is an active acrylamide that promotes the degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins through a post-translational mechanism involving covalent protein engagement. It also inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
- Promotes degradation of NuRD complex proteins.
- Inhibits TMEM173 activation.
- Suppresses activation of NF-κB.
- Blocks nuclear factor of activated T-cells (NFAT) activation.
- Reduces NFATc2 expression in T cells.
- Striking and selective reduction of several proteins in the NuRD complex in a concentration- and time-dependent manner.
Medchemexpress LLC P32 inhibitor M36 | 802555-85-7 | MFCD31666371 | 98.6% | 448.52 g·mol-1 | C23H28N8O2 | 25MG
p32 inhibitor M36 is a small-molecule research reagent that binds directly to the mitochondrial p32 (C1QBP) protein and blocks its association with LyP-1, enabling biochemical and cell-based studies investigating p32-related pathways such as proliferation and viability.
- Binds directly to mitochondrial p32 protein.
- Inhibits p32 association with LyP-1.
- Suitable for cell-based and biochemical assays.
- High purity for research applications.
- Supplied as a solid, convenient for storage and handling.
- Molecular formula C23H28N8O2; molecular weight 448.52 g·mol-1.
Medchemexpress LLC EPQpYEEIPIYL | 147612-86-0 | 99.5% | 1473.52 | 5 MG
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. It activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains.
- Phosphopeptide and Src homology 2 (SH2) domain ligand
- Activates Src family members (e.g., Lck, Hck, Fyn)
- Binds to SH2 domains
- Exhibits highest affinity binding to GST fusion proteins of Lck SH2 domain and Src SH2 domain
- Target: Src
- Pathway: Protein Tyrosine Kinase/RTK