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Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, directed against vascular endothelial growth factor (VEGF)-165. It can be used for the study of neovascular age-related macular degeneration (AMD).
Solid appearance.
White to off-white color.
Inhibits VEGF165-mediated phosphorylation of VEGFR2 and phospholipase Cγ.
Inhibits VEGF165-induced calcium mobilization in human umbilical vein endothelial cells.
Targets vascular endothelial growth factor-165.
Suitable for the study of neovascular age-related macular degeneration.
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