Azolines
Medchemexpress LLC M-peg-thiol (mw 550) | 134874-49-0 | MFCD21363241 | 99.0% | 550 (average) | (C2H4O)nC3H8OS | 1 G
m-PEG-thiol (average molecular weight 550) is a methoxy-terminated polyethylene glycol with a terminal thiol (mPEG-SH) used to introduce PEGylation and thiolation onto biomolecules and nanoparticle surfaces. It is commonly employed to modify DNA for loading onto gold nanorods and to provide a reactive thiol for surface conjugation.
- Provides a terminal thiol for covalent surface conjugation.
- Imparts steric stabilization and improved solubility to modified molecules.
- Average molecular weight of 550 for short PEG linker applications.
- High purity suitable for biochemical and nanomaterials research.
- Available in multiple pack sizes for flexible experimental use.
Medchemexpress LLC Thiol-PEG3-acid | 1347750-82-6 | ≥95.0% | 238.30 | 250 MG
Thiol-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and one for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Purity of ≥95.0%
- Molecular weight of 238.30
- CAS number 1347750-82-6
Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 250 MG
VH 101, thiol is a VHL ligand for the synthesis of PROTACs, suitable for research applications.
- VHL ligand for PROTAC synthesis.
- Appears as a solid.
- Molecular weight of 534.67.
Medchemexpress LLC 2-(2'-Pyridyl)benzimidazole | 1137-68-4 | 99.9% | 195.22 | 5 G
2-(2'-Pyridyl)benzimidazole is a potentially tridentate ligand capable of forming stable complexes with various transition metal ions. It can also function as an anti-inflammatory agent and an inhibitor of *Escherichia coli* methionine aminopeptidase.
- Potentially tridentate ligand
- Forms stable complexes with various transition metal ions
- Can be used as an anti-inflammatory agent
- Functions as an inhibitor of *Escherichia coli* methionine aminopeptidase
Medchemexpress LLC 2,4-Dimethyl-1H-imidazole-5-carbaldehyde | 68282-52-0 | 99.9% | C6H8N2O | 100 MG
2,4-Dimethyl-1H-imidazole-5-carbaldehyde is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and is not sold to patients.
- A drug intermediate for synthesis
- Purity of 99.9%
- Appears as a solid
- Color ranges from light yellow to yellow
- Molecular weight of 124.14
- Chemical formula C6H8N2O
eMolecules 6-Hydroxy-2-mercaptobenzimidazole | 92806-98-9 | MFCD26689414 | 1g
Synthonix - Stock | 6-Hydroxy-2-mercaptobenzimidazole | 1g | 499993738 | H61361 | | 92806-98-9 | MFCD26689414 | 166.200 | C7H6N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC Methimazole 60-56-0 10mM (in 1mL DMSO)
Methimazole is a small-molecule inhibitor targeting intercellular adhesion molecule-1 (ICAM-1) gene transcription It is designed to modulate ICAM-1 expression thereby regulating cell adhesion processes mediated by immunoglobulin superfamily members and integrins such as LFA-1 and Mac-1 Methimazole exerts its biological activity primarily through modulation of signal transducer and activator of transcription 1 (STAT1) In cell-based studies using thyroid cell models methimazole demonstrates inhibitory activity suppressing ICAM-1 mRNA expression induced by interferon-gamma (IFN- ) and H O Based on these pharmacological properties methimazole holds research potential in studying autoimmune thyroid conditions and as an agent to induce hypothyroidism in animal models for thyroid dysfunction research
Medchemexpress LLC Propanoic acid, 3-(2-mercaptoethoxy)- | 1260092-48-5 | 95.0% | 150.20 g/mol | C5H10O3S | 50 MG
Thiol-PEG1-acid (SH-PEG1-COOH) is a short polyethylene glycol derivative bearing a reactive thiol (-SH) and a terminal carboxylic acid (-COOH). It is supplied as a colorless to light yellow liquid and is intended for use as a linker in bioconjugation and PEGylation reactions. Store pure material frozen and protect solutions from long-term degradation.
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 500 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein via a linker.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Cayman Chemical MethImazole 50mg
An inhibitor of thyroid hormone synthesis; a substrate of thyroid peroxidase; traps oxidized iodide and prevents its use by thyroglobulin; inhibits absorption of radiolabeled iodide by the thyroid gland in rats at 0.4 mg/kg; reduces the incidence of lymphocytic thyroiditis in the insulin-dependent type 1 diabetic BB/W rat; has been used to induce hypothyroidism in mice
Medchemexpress LLC Creatinine | 60-27-5 | MFCD00004277 | 99.99% | 25 MG
Creatinine (Standard) is an analytical standard of Creatinine, a breakdown product of creatine phosphate found in muscles. It is commonly used for research and analytical applications, particularly in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Analytical standard for Creatinine
- Suitable for research and analytical applications
- Utilized in HPLC, GC and MS experiments
- Derived from creatine phosphate breakdown
- Store at 2-8°C, protected from light.
Medchemexpress LLC Serotonin hydrochloride | 153-98-0 | 99.9% | 50 MG
Serotonin (5-Hydroxytryptamine) hydrochloride is an analytical standard and a monoamine neurotransmitter in the CNS. It acts as an endogenous 5-HT receptor agonist and a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. This compound is used for research and analytical applications, including qualitative, quantitative, and methodological experiments in HPLC, GC, and MS. Its blood-brain barrier permeability is noted.
- Used as an analytical standard
- Functions as a monoamine neurotransmitter in the CNS
- Acts as an endogenous 5-HT receptor agonist
- Inhibits catechol O-methyltransferase (COMT)
- Suitable for HPLC, GC, and MS research experiments
Medchemexpress LLC Serotonin hydrochloride | 153-98-0 | 100.0% | 100 MG
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter found in the Central Nervous System (CNS) and acts as an endogenous 5-HT receptor agonist, capable of crossing the blood-brain barrier. It also functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
- Monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist
- Exhibits blood-brain barrier permeability
- Functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM
- Inhibits catechol O-methyltransferase (COMT) via non-competitive binding to the site bound by catechol substrates
- Decreases the reaction velocity of COMT at a concentration of 100 μM
- Produces robust hypersensitivity compared to saline-treated controls (p<0.001)