Azolines
eMolecules 25369-78-2 | 5-Chloro-2-mercaptobenzimidazole | MFCD01658762 | 25g
Ambeed | 1-(23-Dihydrobenzo[b][14]dioxin-6-yl)-N-methylmethanamine | 100mg | 599355240 | A531097 | 613656-45-4 | MFCD06260669 | 179.219 | C10H13NO2
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Medchemexpress LLC Thiol-PEG4-acid | 749247-06-1 | 95.0% | 25 MG
Thiol-PEG4-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting a protein for degradation. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity of 95.0%
- Molecular weight: 282.35
- Chemical formula: C11H22O6S
- Appearance: colorless to light yellow liquid
- Storage at 4°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Density: 1.156±0.06 g/cm3
Medchemexpress LLC Thiol-PEG2-acid | 1379649-73-6 | 96.0% | 194.25 | 100 MG
Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs themselves contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein, and they exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. For research use only. We do not sell to patients.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
![Medchemexpress LLC (S)-2-amino-3-(benzo[b]thiophen-3-yl)propanoic acid | 72120-71-9 | MFCD00079684 | 221.28 g/mol | C11H11NO2S | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000300442.png-250.jpg)
Medchemexpress LLC (S)-2-amino-3-(benzo[b]thiophen-3-yl)propanoic acid | 72120-71-9 | MFCD00079684 | 221.28 g/mol | C11H11NO2S | 500 MG
(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is the S-enantiomer of a benzo[b]thiophenyl-substituted alanine derivative supplied for research use. It is intended for biochemical and medicinal chemistry studies; see the datasheet and SDS for handling, storage, and purity details.
- S-enantiomer of a benzo[b]thiophenyl alanine derivative.
- Suitable for biochemical, pharmacological, and medicinal chemistry research.
- Provided as pre-weighed quantities for convenient small-scale experiments.
- Molecular formula C11H11NO2S; molecular weight 221.28 g/mol.
- Documentation available: product datasheet and safety data sheet for handling and storage.
Medchemexpress LLC Propanoic acid, 3-(2-mercaptoethoxy)- | 1260092-48-5 | 95.0% | 150.20 g/mol | C5H10O3S | 50 MG
Thiol-PEG1-acid (SH-PEG1-COOH) is a short polyethylene glycol derivative bearing a reactive thiol (-SH) and a terminal carboxylic acid (-COOH). It is supplied as a colorless to light yellow liquid and is intended for use as a linker in bioconjugation and PEGylation reactions. Store pure material frozen and protect solutions from long-term degradation.
![eMolecules 1858260-93-1 | 6,8-dichloro-3-methylimidazo[1,5-a]pyrazine | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502159162.JPG-250.jpg)
eMolecules 1858260-93-1 | 6,8-dichloro-3-methylimidazo[1,5-a]pyrazine | 1g
Ambeed | 6-Chloroimidazo[12-a]pyridine-3-carbaldehyde | 250mg | 525000850 | A110156 | 29096-59-1 | MFCD09909649 | 180.590 | C8H5ClN2O
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Medchemexpress LLC m-PEG-thiol (MW 10000) | 98.0% | 50 MG
m-PEG-thiol (MW 10000), also known as mPEG-SH (MW 10000), is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are molecules designed to exploit the ubiquitin-proteasome system for targeted protein degradation.
- Purity: 98.0%
- Molecular weight: 10000 (average)
- Appearance: Solid, white to off-white
- Application: Used in the synthesis of PROTACs for targeted protein degradation research
- Storage: 4°C, stored under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month (under nitrogen)
![Medchemexpress LLC Ethanol, 2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]- | 90952-27-5 | 99.9% | 210.29 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365321-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanol, 2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]- | 90952-27-5 | 99.9% | 210.29 | 1 G
Thiol-PEG4-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules connect a ligand for an E3 ubiquitin ligase with a target protein ligand, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Exploits the ubiquitin-proteasome system
- For research use only
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 500 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein via a linker.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 50 MG
VH 101, thiol (compound 20) is a VHL ligand primarily used for the synthesis of PROTACs. This product is intended for research purposes only and not for patient use.
- VHL ligand for PROTAC synthesis
- Intended for research use only
- Molecular weight: 534.67
- Appearance: solid
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL
Medchemexpress LLC m-PEG6-thiol | 441771-60-4 | >98% | C13H28O6S | 250 MG
m-PEG6-thiol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins