Benzothiadiazoles
Search Within Results
1
–
2
of
2
results
1
Medchemexpress LLC FAUC 213 | 337972-47-1 | 99.9% | C18H19ClN4 | 50 MG
FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. It shows less activity on D2 and D3 receptors, with Kis of 3.4 μM and 5.3 μM respectively. This compound can cross the blood-brain barrier (BBB) and exhibits atypical antipsychotic characteristics.
- Highly selective dopamine D4 receptor complete antagonist
- Orally active
- Crosses the blood-brain barrier (BBB)
- Exhibits atypical antipsychotic characteristics
- Inhibits p5-HT1 (Ki=1.2 μM), p5-HT2 (Ki=0.52 μM), and pα1 (Ki=0.27 μM)
- Significantly reduces amphetamine-induced locomotor hyperactivity at 30 mg/kg
- Restores prepulse inhibition reduction caused by apomorphine treatment at 30 mg/kg
2
TARGETMOL CHEMICALS INC PI-273 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIalpha, Inhibits the Growth of Breast Cancer Cells Purity 98.04%