Benzoxadiazoles
Medchemexpress LLC 3-NBD-C12 cholesterol | 186833-02-3 | MFCD00075336 | 10 MG
3-NBD-C12 cholesterol is an NBD-tagged fluorescent cholesterol analog used to study cholesterol uptake, membrane incorporation, intracellular trafficking, and metabolism in biological systems. The NBD fluorophore enables visible-range fluorescence detection for microscopy and spectroscopy; supplied as a solid for research use.
- NBD fluorophore with typical excitation ≈465 nm and emission ≈535 nm
- Suitable for studies of membrane dynamics and cholesterol trafficking
- Soluble in DMF and DMSO for stock solutions with recommended handling
- Solid, yellow to orange appearance for easy visual identification
- Store protected from light; use cold storage for solutions to maintain stability
Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 98.0% | 494.7 g/mol | C25H43NaO6S | 1MG
INT-767 is a semisynthetic bile acid-derived small molecule used in preclinical research as a potent dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5. It modulates bile acid signaling and has been studied in liver and metabolic disease models in vitro and in vivo.
Medchemexpress LLC 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 25 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent used for the sensitive and specific detection of thiols. It has an excitation/emission (Ex/Em) of 380/510 nm. It exhibits low fluorescence background and good stability of fluorophor, making it suitable for various research applications.
- Sensitive and specific detection of thiols.
- Low fluorescence background.
- Good stability of fluorophor.
- Useful for research purposes.
Medchemexpress LLC NBD-556 | 333353-44-9 | 99.6% | C17H24ClN3O2 | 50 MG
NBD-556 is a CD4 mimetic and a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. It demonstrates potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Functions as a CD4 mimetic
- Potent HIV-1 entry inhibitor
- Blocks gp120-CD4 interaction
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion
- Inhibits infection of MT-2 cells by laboratory-adapted HIV-1 strains
- Inhibits CD4-dependent virus in a dose-dependent manner
Apexbio Technology LLC NBD-Cl 10199-89-0 500mg
NBD-Cl (10199-89-0) is a fluorescent labeling reagent that covalently reacts with nucleophilic groups specifically amines and thiols It is designed to derivatize these functional groups enabling detection through the formation of highly fluorescent conjugates NBD-Cl exerts its biological utility primarily through its electrophilic reaction mechanism with free amino and thiol groups in biomolecules No specific experimental model or quantitative activity metric is provided Based on these chemical properties NBD-Cl holds research potential in the labeling and detection of amino acid residues peptides proteins and thiol-containing enzymes as well as in studies of enzyme activities and biomolecular interactions
Sigma Aldrich Fine Chemicals Biosciences 7-Fluorobenzofurazan-4-sulfonic acid ammonium salt >=98% | 84806-27-9 | MFCD02682109 | 25MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium salt >=98% | Purity: >=98% | Mol Wt: 235.19 | 84806-27-9 | MFCD02682109 | 25MG
Medchemexpress LLC 4-nitro-2,1,3-benzoxadiazol-7-amine | 10199-91-4 | 96.7% | 25 MG
NBD-amine is a fluorogenic amine used as a fluorescent probe and labeling reagent. It fluoresces weakly in aqueous solution and strongly in organic solvents, lipid membranes, and other hydrophobic environments, making it suitable for sensing, labeling, and studies of membrane-associated processes.
- Fluorogenic amine that fluoresces weakly in water and strongly in hydrophobic environments.
- Useful as a fluorescent probe and labeling reagent for synthesis and detection.
- Suitable for studying membrane interactions and lipid environments.
- Provided as a solid with purity 96.7% and molecular weight 180.12 g/mol.
- Documentation available: data sheet, safety data sheet (SDS), and certificate of analysis (COA).
Medchemexpress LLC Int-767 | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MG
INT-767 is a semisynthetic dual farnesoid X receptor (FXR) and TGR5 (GPBAR1) agonist used in preclinical research to modulate bile acid signaling, liver, and metabolic pathways. The compound shows mean EC50s of 30 nM for FXR and 630 nM for TGR5, and is supplied as the sodium salt with high reported purity.
Medchemexpress LLC NBD-Pen | 1955505-54-0 | 99.94% | 25 MG
NBD-Pen is the first fluorescence probe for lipid radicals, offering high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). It specifically detects lipid-derived radicals over other reactive species in biological systems. It directly detects lipid radicals in living cells by turn-on fluorescence and can decrease inflammation, apoptosis, and oxidative stress markers. This probe can be studied in various disease models, such as hepatic carcinoma.
- First fluorescence probe for lipid radicals
- High selectivity and sensitivity (λex: 470 nm, λem: 530 nm)
- Detects lipid-derived radicals over other reactive species
- Directly detects lipid radicals in living cells by turn-on fluorescence
- Decreases inflammation, apoptosis, and oxidative stress markers
- Can be studied in various disease models
Medchemexpress LLC MBD (7-(p-methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole) | 33984-50-8 | 99.6% | C14H12N4O4 | 100 MG
MBD is a fluorescent probe utilized for investigating protein and nucleoprotein conformation. It has been successfully applied to bacterial ribosomes as well as bovine trypsinogen and trypsin.
- Fluorescent probe for investigating protein and nucleoprotein conformation.
- Successfully applied to bacterial ribosomes, bovine trypsinogen, and trypsin.
- Strong fluorescence when binding to hydrophobic regions of macromolecules.
Medchemexpress LLC 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | MFCD00036687 | 98.8% | 217.18 | C6H4FN3O3S | 10 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole is a fluorescent reagent for the sensitive and specific detection of thiols. It offers low background fluorescence and a stable fluorophore, making it suitable for thiol derivatization and fluorescence-based analytical applications. The compound is typically supplied as a yellow to green solid and should be protected from light during storage.
- Provides sensitive and specific fluorescence-based thiol detection.
- Low fluorescence background for improved signal-to-noise.
- Stable fluorophore under recommended storage conditions.
- Supplied in small, lab-scale quantities for analytical use.
- Yellow to green solid, easy to handle and store.
Medchemexpress LLC NBD-F (4-fluoro-7-nitrobenzofurazan) | 29270-56-2 | MFCD00010196 | 98.0% | 183.10 | C6H2FN3O3 | 10 MG
NBD-F (4-fluoro-7-nitrobenzofurazan) is a pro-fluorescent derivatization reagent that reacts with primary and secondary amines to produce stable fluorescent adducts. It is used for amino acid analysis, HPLC fluorescence detection, and other sensitive analytical applications.
- Pro-fluorescent reagent for derivatizing primary and secondary amines.
- Excitation 445 nm, emission 515 nm for fluorescence detection.
- Molecular weight 183.10 g/mol; formula C6H2FN3O3.
- Typical purity approximately 98.0%.
- Light yellow solid; store protected from light at 4°C; freeze solutions for long-term storage.
Medchemexpress LLC N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-phosphatidylethanolamine, triethylammonium salt | 178119-00-1 | MFCD00467850 | 95.0% | 956.26 g/mol | C49H90N5O11P | 10 MG
NBD-PE is an NBD-labeled phosphatidylethanolamine fluorescent probe used to label membranes and monitor lipid trafficking and membrane dynamics. It exhibits environment-sensitive green fluorescence (excitation ~463 nm, emission ~526 nm) and is supplied as a solid for laboratory use. CAS 178119-00-1; molecular weight ~956.26 g/mol.
- Green fluorescent NBD label with excitation ~463 nm and emission ~526 nm.
- Integrates into lipid bilayers for membrane labeling and tracking.
- Environment-sensitive fluorescence suitable for monitoring membrane order.
- Available in small laboratory quantities for experimental use.
- Supplied as a solid with a brown to black physical appearance.
- CAS 178119-00-1; molecular weight 956.26 g/mol.
Aobchem 2-Bromo-3-carboxypyridine-5-boronic acid | ≥97% | CAS 1451393-49-9 | C6H5BBrNO4 | 1g
2-Bromo-3-carboxypyridine-5-boronic acid | ≥97% | CAS 1451393-49-9 | C6H5BBrNO4 | 1g
![Aobchem B-[3-(2-Pyridinyloxy)phenyl]boronic acid | ≥95% | CAS 2040475-93-0 | C11H10BNO3 | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000924241.png-250.jpg)
Aobchem B-[3-(2-Pyridinyloxy)phenyl]boronic acid | ≥95% | CAS 2040475-93-0 | C11H10BNO3 | 250mg
B-[3-(2-Pyridinyloxy)phenyl]boronic acid | ≥95% | CAS 2040475-93-0 | C11H10BNO3 | 250mg