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Organic heterocyclic compounds that consist of benzene fused with an oxazines; oxazines are a six-membered ring with four carbon atoms, one oxygen atom, and one nitrogen atom.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase leading to mitotic disasters polynuclearization and loss of cancer cell dryness. FiVe1 selectively and irreversibly inhibit the growth of mesenchymal transformed breast cancer cells (FOXC2-HMLER cell IC50=234nM) and soft tissue sarcomas of different histological subtypes. purity: 98%
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