Biotin and derivatives
Medchemexpress LLC TCO-NHS Ester (axial) | 1610931-22-0 | C13H17NO5 | 25 MG
TCO-NHS Ester axial is a click chemistry reagent that functions as a building block in amine reactions. It contains TCO groups, which are capable of undergoing inverse electron demand Diels-Alder (iEDDA) reactions with molecules that contain Tetrazine groups. This product has a purity of ≥98.0% and is intended for research use only.
- Functions as a building block in amine reactions
- Contains TCO groups capable of inverse electron demand Diels-Alder (iEDDA) reactions with Tetrazine groups
- Purity of ≥98.0%
- Appears as a white to off-white solid
- Intended for research use only
Medchemexpress LLC Norbornene-NHS | 1888335-48-5 | C12H13NO5 | 100 MG
Norbornene-NHS is a click chemistry reagent that functions as a dienophile. It is utilized for conjugation through copper-free Click reactions with tetrazines.
- Classified as a click chemistry reagent.
- Acts as a dienophile.
- Used for conjugation.
- Conjugation occurs via copper-free click reactions.
- Reacts with tetrazines in the conjugation process.
- For research use only and not intended for human use.
![eMolecules 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 480169795](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000161303.jpg-250.jpg)
eMolecules 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 480169795
D-Biotin | Oakwood Chemicals | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 480169795
Medchemexpress LLC Bz-(Me)Tz-NHS | 1454558-58-7 | MFCD00076258 | C₁₉H₂₀N₅O₅S | 25 MG
Bz-(Me)Tz-NHS is a click chemistry reagent that contains a methyltetrazine group. It functions as a 3rd generation Click-Linker for Cu-free click conjugation, primarily used in antibody-drug conjugate (ADC) related research.
- Contains a methyltetrazine group
- Functions as a 3rd generation Click-Linker
- Designed for Cu-free click conjugation
- Used in antibody-drug conjugate (ADC) related research
Medchemexpress LLC Biotin-PEG3-acid 1g | 252881-76-8 | 447.55 | C19H33N3O7S | 1 G
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker used to introduce a biotin tag with a short PEG3 spacer in PROTAC synthesis and bioconjugation workflows. The material is supplied as a 1 g purified solid (typical purity 98.0%) with molecular weight 447.55 g/mol and chemical formula C19H33N3O7S, and is accompanied by a batch-specific certificate of analysis.
- Provides a biotin handle separated by a PEG3 spacer to reduce steric hindrance
- Designed for incorporation into PROTACs and other bioconjugates
- Improves aqueous solubility compared with direct biotinylation
- Typically supplied with batch certificate showing ~98.0% purity
- Solid form with known molecular weight and formula for formulation planning
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 g·mol⁻¹ | C28H30N4O3S | 5MG
DBCO-biotin is a dibenzocyclooctyne (DBCO)-linked biotin reagent designed for copper-free, bioorthogonal click chemistry. It enables rapid biotinylation of azide-functionalized molecules for affinity capture, labeling, and conjugation workflows, and is suitable as a linker component in PROTAC and bioconjugation applications.
- Enables copper-free click conjugation to azide-containing molecules.
- Provides a biotin tag for affinity capture and detection.
- High reported purity for consistent experimental performance.
- Available in small research quantities for method development.
- Solid, easy-to-handle form with standard storage recommendations.