Biotin and derivatives
Advanced Chem Tech Succinimidyl 6- biotinamido he, Advanced ChemTech
Molecular Weight (g/mol): 454.5
Advanced Chem Tech Biotin-OSu, Advanced ChemTech
Molecular Weight (g/mol): 341.38
IBA LifeSciences Biotin powder; 5 g
Biotin is a water-soluble B-complex vitamin, also known as vitamin B7 or vitamin H. It binds to the biotin-binding pockets of streptavidin, Strep-Tactin, and Strep-TactinXT with different affinities. As a result, it allows the efficient elution of Strep-tagII or Twin-Strep-tag fusion proteins from Strep-TactinXT, while maintaining the reusability of the resin. It can be used for preparation of Strep-TactinXT elution buffer, Buffer BXT. In addition, biotin can be used for elution of biotinylated proteins from Strep-Tactin, where it binds irreversibly to the resin. Hence, Strep-Tactin cannot be regenerated in this kind of application.
IBA LifeSciences Biotin powder; 2 g
Biotin is a water-soluble B-complex vitamin, also known as vitamin B7 or vitamin H. It binds to the biotin-binding pockets of streptavidin, Strep-Tactin, and Strep-TactinXT with different affinities. As a result, it allows the efficient elution of Strep-tagII or Twin-Strep-tag fusion proteins from Strep-TactinXT, while maintaining the reusability of the resin. It can be used for preparation of Strep-TactinXT elution buffer, Buffer BXT. In addition, biotin can be used for elution of biotinylated proteins from Strep-Tactin, where it binds irreversibly to the resin. Hence, Strep-Tactin cannot be regenerated in this kind of application.
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 g/mol | C38H64N2O21 | 25 MG
Bis-PEG13-NHS ester is a PEG-based N-hydroxysuccinimide (NHS) ester linker for research use in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Provides a bifunctional PEG13 spacer for conjugation to amines.
- Reactive NHS ester termini enable efficient coupling.
- High purity suitable for research applications.
- Molecular weight approximately 884.92 g/mol; molecular formula C38H64N2O21.
- Available in small pack sizes for research-scale synthesis.
![Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203007.png-250.jpg)
Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG
Bis-PEG2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester reactive groups at both ends, designed for antibody-agent conjugation via amine-coupling chemistry for research use.
- Noncleavable two-unit PEG linker for antibody-agent conjugation.
- N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling.
- High purity, 99.2%.
- Molecular weight 400.34 g/mol.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation may be required.
- Storage: powder at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple pack sizes, including 250 MG.
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate | 107348-47-0 | MFCD28398150 | 98.0% | 326.40 g/mol | C13H14N2O4S2 | 50 MG
PPC-NHS ester is a cleavable linker reagent containing an N-hydroxysuccinimide (NHS) ester and a pyridin-2-yldisulfanyl cleavable moiety; it is used to attach cytotoxic payloads to antibodies and enable payload release under reducing conditions.
- Cleavable disulfide linker enabling intracellular release of payloads
- N-hydroxysuccinimide (NHS) ester reactive toward primary amines
- Molecular formula C13H14N2O4S2, molecular weight 326.40 g/mol
- Purity 98.0%
- Supplied as a white to off-white solid, 50 MG per package
- Storage: powder -20°C (stable 3 years); in solvent -80°C (6 months), -20°C (1 month)
Medchemexpress LLC Sulfo-TAG NHS ester (disodium) | 482618-42-8 | 88.4% | 1185.12 g/mol | C43H39N7Na2O16RuS4 | 1 MG
Sulfo-TAG NHS ester (disodium) is a water-soluble N-hydroxysuccinimide (NHS) ester reagent for covalent labeling of proteins and antibodies via primary amine groups. The reagent contains a ruthenium-based electrochemiluminescent tag that enables sensitive electrochemiluminescence (ECL) detection when conjugated to antibodies. Supplied as a solid for research use; handle and store according to the supplier's SDS and COA.
- Couples to primary amine groups on proteins and antibodies for stable conjugation.
- Enables electrochemiluminescence (ECL) detection when attached to antibodies.
- Water-soluble formulation suitable for aqueous conjugation reactions.
- Provided with storage recommendations to maintain stability.
- Supplied with certificate of analysis (COA) and safety data sheet (SDS) specifying purity and molecular data.
![Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203370.png-250.jpg)
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG
BCN-SS-NHS is a cleavable linker reagent containing an NHS ester and a strained bicyclo[6.1.0]nonyne (BCN) moiety. It is used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry and to introduce a cleavable disulfide-containing linker arm in bioconjugation and antibody-drug conjugate synthesis.
- Used for SPAAC click chemistry
- Contains an NHS ester for efficient amine coupling
- Includes a disulfide-cleavable linker for intracellular release
- Suitable for antibody-drug conjugate and bioconjugation workflows
- Available in small-scale research quantities
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | MFCD21363287 | 98.0% | 884.92 | C38H64N2O21 | 50 MG
Bis-PEG13-NHS ester is a bifunctional PEG-based linker containing N-hydroxysuccinimide (NHS) ester reactive groups that enable efficient amine conjugation; it is used as a cleavable linker in antibody-drug conjugate and PROTAC synthesis and for general bioconjugation chemistry.
- contains N-hydroxysuccinimide (NHS) ester reactive groups.
- functions as a cleavable linker for ADC and PROTAC synthesis.
- molecular formula C38H64N2O21, molecular weight 884.92.
- cas number 2221949-00-2 for unambiguous identification.
- purity 98.0% suitable for research applications.
- available in a 50 MG pack suitable for lab-scale synthesis.
- intended for research use only; not for human or clinical use.