Biotin-PEG12-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. This compound utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
- For research use only