Biotin and derivatives
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Medchemexpress LLC AF647-NHS ester | 407627-60-5 | 99.7% | 956.09 | C40H49N3O16S4 | 10 MG
AF647-NHS ester is an N-hydroxysuccinimide ester of a far-red fluorescent dye used to covalently label amine-containing biomolecules for fluorescence imaging and detection. It is supplied as a solid optimized for conjugation to proteins, antibodies, and peptides.
- Far-red excitation at 635 nm (instantaneous 620 nm) suitable for 633-647 nm lasers.
- High purity by HPLC: 99.74%.
- Molecular weight 956.09; formula C40H49N3O16S4.
- Appearance: dark purple to black solid.
- Storage: long-term at 4 °C sealed; in solvent, -80 °C up to 6 months.
- Supplied as 10 MG vials.
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Medchemexpress LLC NHS-modified MMAF TFA | 96.0% | 1165.34 g/mol | C57H87F3N8O14 | 5 MG
NHS-modified MMAF TFA is a trifluoroacetate (TFA) salt intermediate used in the synthesis of antibody-drug conjugates (ADCs), notably for preparing anti-mesothelin binder-agent conjugates.
- Purity 96.03%
- Molecular weight 1165.34 g/mol
- Chemical formula C57H87F3N8O14
- Physical state: white to off-white solid
- Available package sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg
- Solubility in DMSO: 16 mg/mL (13.73 mM); sonication assisted
- Storage: -20°C protected from light; in solvent store -80°C (6 months) or -20°C (1 month)
- Available documentation: data sheet, SDS, COA, HNMR, RP-HPLC, LCMS, product usage guide
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Medchemexpress LLC Bis-PEG2-NHS ester | 65869-63-8 | 99.2% | 400.34 | C16H20N2O10 | 100 MG
Bis-PEG2-NHS ester is a non-cleavable two-unit polyethylene glycol (PEG) linker intended for antibody-agent conjugation (ADC) research applications. It provides NHS ester reactive groups for coupling to amines and is used in bioconjugation workflows to construct antibody-drug conjugates.
- Non-cleavable 2-unit PEG linker for antibody-agent conjugation.
- Purity 99.24% as reported by the manufacturer.
- Molecular weight 400.34 g/mol.
- Chemical formula C16H20N2O10.
- CAS number 65869-63-8.
- Appearance solid, white to off-white.
- Storage: powder -20°C (stable for 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Package size options include 100 mg, 250 mg, 1 g, 5 g, 10 g, and 50 g.
- Manufacturer documents available: data sheet, safety data sheet, certificate of analysis, handling instructions, H NMR, RP-HPLC, and mass spectrometry data.