Dithioles
Sigma Aldrich 4-Benzyloxoy-3-methoxyphenylboronic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Apexbio Technology LLC Malotilate 59937-28-9 5mg
Malotilate (CAS 59937-28-9) is a diethyl ester derivative investigated for its hepatotropic properties notably its ability to enhance protein metabolism and promote hepatocyte regeneration Mechanistically Malotilate modulates vascular endothelial cell function reducing endothelial permeability induced by serum deprivation and inhibiting the invasion of tumor cells through endothelial barriers as demonstrated in rat lung endothelial cell models In vivo studies show that oral administration of Malotilate significantly suppresses pulmonary metastasis in rat models of mammary carcinoma Clinically Malotilate has been reported to accelerate the recovery of impaired protein metabolism in alcoholic liver disease suggesting its utility in hepatic disease research
Medchemexpress LLC 1,3-propane-dithiol-d6 | 1219803-51-6 | 98.3% | 114.26 | C3H2D6S2 | 10 MG
1,3-Propane-dithiol-d6 is a deuterium-labeled small molecule used as a tracer and internal standard for quantitative analytical techniques. It is supplied as a liquid for research use only, with manufacturer documentation providing storage, handling, and analytical report options. The compound is intended to support precise quantitation and method development in trace analysis workflows.
- Deuterium-labeled internal standard for accurate quantitation.
- Suitable as a tracer in analytical workflows.
- Compatible with NMR, GC-MS, and LC-MS analyses.
- Available in small-mass packages appropriate for trace-level work.
- Storage stability under recommended cold conditions.
- Datasheet and analytical reports available on request.
Medchemexpress LLC Thiolutin | 87-11-6 | 25 MG
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. It acts as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory effects. It suppresses the interaction between BRCC36 and HMGCR, inhibiting HCC growth, attenuating pyroptosis and NLRP3 inflammasome activation, and alleviating renal injury and inflammatory processes. Thiolutin is also an anti-angiogenic compound that can ease Doxorubicin-induced cardiotoxicity (DOXIC).
- Potent inhibitor of bacterial and yeast RNA polymerases.
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome.
- Exhibits anti-inflammatory properties and attenuates pyroptosis.
- Suppresses BRCC36 and HMGCR interaction, inhibiting HCC growth.
- Alleviates renal injury in IgAN and Doxorubicin-induced cardiotoxicity.
- Can be produced by Streptomyces.
Medchemexpress LLC Malotilate (NKK 105) | 59937-28-9 | 99.5% | C12H16O4S2 | 1 ML
Malotilate (NKK 105) is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM, preventing hepatocytic injury in alcohol-pyrazole hepatitis and reducing hepatic acetaldehyde levels.
- Prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis
- Decreases hepatic acetaldehyde levels
- Prevents the retention of transferrin in the hepatocytes
- Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
- Demonstrated to prevent acute experimental liver injury induced by various hepatotoxic compounds
Cayman Chemical luteosporeus ThIolutIn 10mg
A natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases (IC50 = 3 μg/ml); used for the analysis of mRNA stability; inhibits endothelial cell adhesion (IC50 induced angiogenesis in mice by inhibiting Hsp27 interactions with cytoskeletal elements
Medchemexpress LLC Malotilate | 59937-28-9 | 99.47% | C12H16O4S2 | 5 MG
Malotilate | 59937-28-9 | 99.47% | C12H16O4S2 | 5 MG
Cayman Chemical 2H 2H 3H 3HPerfluorohexnoIc 5g
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
eMolecules 3H-1,2-Benzodithiol-3-one | 1677-27-6 | MFCD00134412 | 10g
Oakwood Chemicals | 3H-1,2-Benzodithiol-3-one | 10g | 480149743 | 099152 | | 1677-27-6 | MFCD00134412 | 168.230 | C7H4OS2
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TARGETMOL CHEMICALS INC THIOLUTIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly. purity: 98%
Medchemexpress LLC Malotilate | 59937-28-9 | 99.47% | C12H16O4S2 | 25 MG
Malotilate is an orally active hepatotropic and anti-fibrotic agent that selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing transferrin retention in hepatocytes.
- Selectively inhibits 5-lipoxygenase (5-LOX)
- Prevents hepatocytic injury in alcohol-pyrazole hepatitis
- Decreases hepatic acetaldehyde levels
- Prevents retention of transferrin in hepatocytes
- Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
- Prevents acute experimental liver injury induced by various hepatotoxic compounds
- Normalizes reduced serum cholesterol levels in rats with carbon tetrachloride-induced liver damage
TARGETMOL CHEMICALS INC MALOTILATE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis. purity: 99%
Apexbio Technology LLC Thiolutin(Synonyms: Acetopyrrothin, Farcinicin, Aureothricin, Antibiotic 810, Pyrrothine, Nocathiacin), 5mg, CAS: 32087.
Thiolutin (CAS 87-11-6) is a microbial-derived antibiotic known to inhibit RNA polymerase activity in bacteria It also interferes with the adhesion process of human umbilical vein endothelial cells (HUVECs) to vitronectin displaying an IC value of approximately 0 83 mM and subsequently reduces cellular paxillin expression Through these actions thiolutin effectively diminishes tumor cell-induced angiogenesis making it a useful tool compound in research exploring transcription regulation cell adhesion processes and tumor-related angiogenic mechanisms
Apexbio Technology LLC Thiolutin(Synonyms: Acetopyrrothin, Farcinicin, Aureothricin, Antibiotic 810, Pyrrothine, Nocathiacin), 1mg, CAS: 32087.
Thiolutin (CAS 87-11-6) is a microbial-derived antibiotic known to inhibit RNA polymerase activity in bacteria It also interferes with the adhesion process of human umbilical vein endothelial cells (HUVECs) to vitronectin displaying an IC value of approximately 0 83 mM and subsequently reduces cellular paxillin expression Through these actions thiolutin effectively diminishes tumor cell-induced angiogenesis making it a useful tool compound in research exploring transcription regulation cell adhesion processes and tumor-related angiogenic mechanisms