Dithioles
Sigma Aldrich 3H-1,2-Benzodithiol-3-one
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Accela Chembio Inc Tetrathiafulvalene | 5g | 31366-25-3 | MFCD00005492 | 97+% | Shelf Life: 540 Days | Light Sensitive/nitrogen Or Argon/+4
Tetrathiafulvalene | 5g | 31366-25-3 | MFCD00005492 | 97+% | Shelf Life: 540 Days | Light Sensitive/nitrogen Or Argon/+4
Medchemexpress LLC Malotilate | 59937-28-9 | C12H16O4S2 | 50 MG
Malotilate is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It helps prevent the development of hepatocytic injury in alcohol-pyrazole hepatitis by reducing hepatic acetaldehyde levels and preventing the retention of transferrin in hepatocytes.
- Selectively inhibits 5-lipoxygenase (5-LOX) (IC50=4.7 μM).
- Prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels.
- Prevents the retention of transferrin in the hepatocytes.
Medchemexpress LLC Malotilate | 59937-28-9 | 99.5% | C12H16O4S2 | 100 MG
Malotilate is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes. For research use only.
- Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
- Stimulates 12- and 15-lipoxygenase pathways
- Prevents acute experimental liver injury induced by various hepatotoxic compounds
- Normalizes lowered serum cholesterol in rats with hypocholesterolemia
- Normalizes inhibition of triglyceride secretion from livers in rats with CCl4-induced liver damage
Chem-Impex International, Inc. 4-Propylbenzoic acid | 2438-05-3 | MFCD00013996 | 25G
4-Propylbenzoic acid, 2438-05-3, MFCD00013996, 25G
Medchemexpress LLC Thiolutin (acetopyrrothin) | 87-11-6 | 1 ML
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. It is produced by Streptomyces. Thiolutin inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM). It acts as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory effects and effectively suppressing the interaction between BRCC36 and HMGCR, thereby inhibiting HCC growth.
- Potent inhibitor of bacterial and yeast RNA polymerases.
- Inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM).
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects.
- Suppresses the interaction between BRCC36 and HMGCR, inhibiting HCC growth.
- Attenuates pyroptosis and NLRP3 inflammasome activation.
- Alleviates renal injury and inflammatory process in IgAN.
- Anti-angiogenic compound that can ease doxorubicin-induced cardiotoxicity (DOXIC).
Chem-Impex International, Inc. 3H-1,2-Benzodithiol-3-one-1,1-dioxide | 66304-01-6 | MFCD00132960 | 25G
3H-1,2-Benzodithiol-3-one-1,1-dioxide, 66304-01-6, MFCD00132960, 25G
Cayman Chemical 2H 2H 3H 3HPerfluorohexnoIc 1g
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
Medchemexpress LLC Thiolutin (Acetopyrrothin) | 87-11-6 | 10 MG
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. Produced by Streptomyces, it functions as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory and anti-angiogenic properties.
- Sulfur-containing antibiotic
- Potent inhibitor of bacterial and yeast RNA polymerases
- Inhibits AMSH and Rpn11
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome
- Anti-inflammatory effects
- Inhibits HCC growth by suppressing BRCC36 and HMGCR interaction
- Attenuates pyroptosis and NLRP3 inflammasome activation
- Alleviates renal injury and inflammatory processes in IgAN
- Acts as an anti-angiogenic compound
- Eases Doxorubicin-induced cardiotoxicity