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Azimilide dihydrochloride is a class III antiarrhythmic agent that functions by blocking potassium channels in the heart. It is a dual blocker of IKs (IC50 = 2.6 μM) and IKr (IC50 = 1 μM), and also inhibits HERG channels, L-type calcium current (ICa), and sodium current (INa). This compound is used for the study of atrial fibrillation and ventricular fibrillation.
Class III antiarrhythmic agent
Blocks potassium channels in the heart
Dual blocker of IKs and IKr
Inhibits HERG channel
Inhibits L-type calcium current (ICa) and sodium current (INa)
Can be used for the study of atrial fibrillation and ventricular fibrillation
Purity: 98.17%
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Azimilide dihydrochloride is the dihydrochloride salt of azimilide, a class III antiarrhythmic research compound that blocks cardiac potassium currents. It is used in vitro to study cardiac electrophysiology, ion channel pharmacology, and mechanisms of arrhythmia in cellular and tissue models.
Dual IKs and IKr (hERG) blocker useful for cardiac electrophysiology studies.
Characterized IC50 values enable comparative ion channel pharmacology.
Offered as solid and as a ready-to-use 10 mM solution for assay flexibility.
Stable dihydrochloride salt with defined molecular weight and formula for reproducible dosing.
Suitable for in vitro investigations of atrial and ventricular fibrillation mechanisms.
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Medchemexpress, HY-18600A 5mg Azimilide (Dihydrochloride) CAS:149888-94-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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