(S)-Terazosin is the active S-enantiomer of Terazosin. It functions as a potent and high-affinity α-adrenoceptor antagonist, demonstrating specific Ki values for α1a, α1b, and α1d-adrenoceptors, as well as high affinity for α2a, α2B, and α2c-adrenoceptors. Its mechanism involves antagonism of α1-adrenoceptor subtypes in isolated tissues and antagonism at rat atrial α2B and rat vas deferens α1A and α2A receptors.
- Active S-enantiomer of Terazosin
- Potent α-adrenoceptor antagonist
- High-affinity for α1a, α1b, and α1d-adrenoceptors
- High-affinity for α2a, α2B, and α2c-adrenoceptors
- Antagonism at rat atrial α2B receptor
- Antagonism at rat vas deferens α1A and α2A receptors