Imidazopyridines
![Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000393984.png-250.jpg)
Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable inhibitor of DGAT-1. It can be used for research on obesity, dyslipidemia, and metabolic syndrome.
- Potent, selective, and orally bioavailable inhibitor of DGAT-1.
- Inhibits human DGAT-1 with an IC50 of 38 nM.
- Inhibits rat DGAT-1 with an IC50 of 120 nM.
- Supports research into obesity.
- Supports research into dyslipidemia.
- Supports research into metabolic syndrome.
- Reduces cumulative body weight gain in DIO rats.
- Reduces weight gain and plasma triglycerides.
- Improves lipid profiles.
eMolecules 1394382-56-9 | Pyridine-2,6-dicarboxamidine dihydrochloride | ChemScene236.100 | C7H11Cl2N5 | 98.000 | Cl.Cl.NC(=N)c1cccc(n1)C(N)=N | 1g | 712797332
Pyridine-2,6-dicarboxamidine dihydrochloride | ChemScene | 1394382-56-9236.100 | C7H11Cl2N5 | 98.000 | Cl.Cl.NC(=N)c1cccc(n1)C(N)=N | 1g | 712797332
Medchemexpress LLC Diethyl pyridine-2,4-dicarboxylate | 41438-38-4 | MFCD00152168 | 99.8% | 223.23 g/mol | C11H13NO4 | 1 ML
Diethyl pyridine-2,4-dicarboxylate is a small-molecule prolyl 4-hydroxylase-directed proinhibitor used to inhibit prolyl hydroxylation and procollagen processing in biological studies. It is offered as both a solid and as a ready-to-use 10 mM solution in DMSO for screening and cellular assays. Molecular formula C11H13NO4; molecular weight 223.23 g/mol.
Medchemexpress LLC PDE2A-IN-3 | 1426833-08-0 | 295.73 | 100 MG
PDE2A-IN-3 is a selective phosphodiesterase 2A (PDE2A) inhibitor with IC50s of 69 nM and 1762 nM for PDE2A and PDE10, respectively. It can be used for the study of neurological and psychiatric disorders.
- Selective phosphodiesterase 2A (PDE2A) inhibitor
- IC50 of 69 nM for PDE2A
- IC50 of 1762 nM for PDE10
- Suitable for studying neurological and psychiatric disorders
Medchemexpress LLC 3-Cl-Pyridine-amide-acrylaldehyde-piperazine | 99.30% | 294.74 | 100 MG
3-Cl-Pyridine-amide-acrylaldehyde-piperazine is a synthetic intermediate of LO-4-25. LO-4-25 is an androgen receptor (AR) DNA binding domain ligand linked via a linker to the truncated fumaramide handle. LO-4-25 shows robust degradation of both AR and AR-V7 in 22Rv1 cells.
- Synthetic intermediate of LO-4-25
- Androgen receptor (AR) DNA binding domain ligand
- Shows robust degradation of both AR and AR-V7 in 22Rv1 cells
- For research use only
Medchemexpress LLC Samatasvir | 1312547-19-5 | 99.4% | 885.06 | 5 MG
Samatasvir is a potent, orally active NS5A inhibitor of HCV replication. It is effective and selective against infectious HCV and replicons, with EC50s ranging from 2 to 24 pM in genotype 1 through 5 replicons.
- Potent, orally active NS5A inhibitor of HCV replication.
- Effective and selective against infectious HCV and replicons.
- Retains full activity in the presence of HIV and hepatitis B virus (HBV) antivirals.
- Not cross-resistant with HCV protease, nucleotide, and nonnucleoside polymerase inhibitor classes.
Medchemexpress LLC CXCR7 antagonist-1 | 2990472-61-0 | 99.4% | C21H20ClFN6O | 10MG
CXCR7 antagonist-1 hydrochloride is a small-molecule antagonist of the chemokine receptor CXCR7 that inhibits binding of the chemokines SDF-1 (CXCL12) and I-TAC (CXCL11). It is supplied as the hydrochloride salt for research use in studies of tumor cell proliferation, tumor formation, and inflammatory disease pathways.
- Antagonist of the CXCR7 chemokine receptor.
- Inhibits SDF-1 (CXCL12) and I-TAC (CXCL11) binding to CXCR7.
- Provided as the hydrochloride salt in a solid form.
- High purity (99.4%).
- Supplied in small research-scale quantities suitable for in vitro assays.