Imidazopyridines
eMolecules Medchem Express / Soraprazan / 1mg / 446255407 / HY-100414 / / 261944-46-1 / MFCD21607984 / 367.449 / C21H25N3O3
Medchem Express / Soraprazan / 1mg / 446255407 / HY-100414 / / 261944-46-1 / MFCD21607984 / 367.449 / C21H25N3O3
Medchemexpress LLC CXCR7 modulator 1 10mg | 2231812-31-8 | 10MG
CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator with a Ki of 9 nM[1
![eMolecules Ambeed / 6-Bromo-3-fluoroimidazo[12-a]pyridine / 100mg / 599120090 / A819444 / / 2001563-56-8 / MFCD30829494 / 215.025 / C7H4BrFN2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446478.PNG-250.jpg)
eMolecules Ambeed / 6-Bromo-3-fluoroimidazo[12-a]pyridine / 100mg / 599120090 / A819444 / / 2001563-56-8 / MFCD30829494 / 215.025 / C7H4BrFN2
Ambeed / 6-Bromo-3-fluoroimidazo[12-a]pyridine / 100mg / 599120090 / A819444 / / 2001563-56-8 / MFCD30829494 / 215.025 / C7H4BrFN2
Medchemexpress LLC (R)-IL-17 modulator 4 | 2446804-29-9 | 99.6% | 474.60 g·mol⁻1 | C27H34N6O2 | 5 MG
(R)-IL-17 modulator 4 is a research-stage, orally active small molecule modulator of IL-17 signaling supplied as an off-white to gray solid for preclinical laboratory use. Supporting analytical and safety documentation is provided by the manufacturer.
![eMolecules N-(5-BROMOIMIDAZO[1,2-A]PYRIDIN-2-YL)-2,2,2-TRIFLUOROACETAMIDE | 1936365-02-4 | MFCD28405202 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502182283.JPG-250.jpg)
eMolecules N-(5-BROMOIMIDAZO[1,2-A]PYRIDIN-2-YL)-2,2,2-TRIFLUOROACETAMIDE | 1936365-02-4 | MFCD28405202 | 1g
AstaTech | N-(5-BROMOIMIDAZO[1,2-A]PYRIDIN-2-YL)-2,2,2-TRIFLUOROACETAMIDE | 1g | 273176175 | 89372 | 95.000 | 1936365-02-4 | MFCD28405202 | 308.058 | C9H5BrF3N3O
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Medchemexpress LLC DGAT1-IN-3 | 939375-07-2 | 99.9% | 420.39 | 50 MG
DGAT1-IN-3 is a potent, selective and orally bioavailable inhibitor of DGAT-1, with IC50s of 38 nM for human DGAT-1 and 120 nM for rat DGAT-1. It could be used to research of obesity, dyslipidemia, and metabolic syndrome.
- IC50 of 38 nM for human DGAT-1; 120 nM for rat DGAT-1
- Inhibits human DGAT1 expressed in CHOK1 cells with an EC50 of 0.66 μM
- Blocks the human ether-a-go-go-related gene (hERG) encoded potassium channel with an IC20 of 0.2 μM
- Reduces weight gain and plasma triglycerides, and improves lipid profile (5-50 mg/kg; p.o once daily for three weeks)
- Exhibits good oral bioavailability (77%) and a maximum exposure level in plasma (Cmax) of 24 μM (50 mg/kg; p.o)
- Exhibits terminal elimination half-lives (1.95 h) and low clearance (13.5 mL/min/kg) (5 mg/kg; i.v)
![eMolecules (2-Imidazo[2,1-b][1,3]thiazol-6-yl-1-methylethyl)amine dihydrochloride | 1332529-24-4 | MFCD18071257 | 10g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502193012.JPG-250.jpg)
eMolecules (2-Imidazo[2,1-b][1,3]thiazol-6-yl-1-methylethyl)amine dihydrochloride | 1332529-24-4 | MFCD18071257 | 10g
Combi-Blocks | (2-Imidazo[2,1-b][1,3]thiazol-6-yl-1-methylethyl)amine dihydrochloride | 10g | 401041668 | QY-9134 | 95.000 | 1332529-24-4 | MFCD18071257 | 254.170 | C8H13Cl2N3S
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Medchemexpress LLC CXCR7 modulator 1 (compound 25) | 2231812-31-8 | 99.5% | 914.07 | C48H57F2N7O7S | 100 MG
CXCR7 modulator 1 is a potent, orally bioavailable peptoid-hybrid small molecule that modulates the chemokine receptor CXCR7 (reported Ki = 9 nM). It is intended for research use in studies of GPCR signaling and immunology/inflammation.
- Potent CXCR7 modulator with reported Ki of 9 nM.
- Orally bioavailable peptoid-hybrid small molecule.
- Peptoid-hybrid scaffold suitable for medicinal chemistry studies.
- High purity (99.5%) for research applications.
- Molecular weight 914.07, molecular formula C48H57F2N7O7S.
- Suitable for GPCR signaling and immunology or inflammation research.
![Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000394191.png-250.jpg)
Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 | 5 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable inhibitor of DGAT-1, with IC50s of 38 nM for human DGAT-1 and 120 nM for rat DGAT-1. It can be used for research on obesity, dyslipidemia, and metabolic syndrome.
- Potent, selective, and orally bioavailable inhibitor of DGAT-1.
- IC50s: 38 nM (human DGAT-1); 120 nM (rat DGAT-1).
- Reduces weight gain and plasma triglycerides, and improves lipid profile in animal models.
- Exhibits good oral bioavailability (77%) and a maximum exposure level in plasma (Cmax) of 24 μM (50 mg/kg; p.o).
- Exhibits terminal elimination half-lives (1.95 h) and low clearance (13.5 mL/min/kg) (5 mg/kg; i.v).
- Appearance: solid, light yellow to yellow color.
![eMolecules Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid | 53572-98-8 | MFCD03419463 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502185185.JPG-250.jpg)
eMolecules Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid | 53572-98-8 | MFCD03419463 | 1g
Combi-Blocks, Inc. | Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid | 1g | 569298138 | SS-6204 | 95.000 | 53572-98-8 | MFCD03419463 | 168.170 | C6H4N2O2S
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