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Imidazopyrimidines

Organic heterocyclic compounds that contain an imidazole ring fused to a pyrimidine ring. Imidazole is five-membered ring with three carbon atoms and two nitrogen atoms; pyrimidine is a six-membered ring with four carbon atoms and two nitrogen atoms.

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1

Selleck Chemical LLC IBMX

IBMX (Isobutylmethylxanthine 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6 5 1 2 26 3 3 9 and 31 7 5 3 M for PDE3 4 and 5 respectively It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist

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2

Selleck Chemical LLC IBMX

IBMX (Isobutylmethylxanthine 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6 5 1 2 26 3 3 9 and 31 7 5 3 M for PDE3 4 and 5 respectively It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist

ENCOMPASS_PREFERRED
3

Selleck Chemical LLC IBMX

IBMX (Isobutylmethylxanthine 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6 5 1 2 26 3 3 9 and 31 7 5 3 M for PDE3 4 and 5 respectively It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist

ENCOMPASS_PREFERRED
4

Apexbio Technology LLC IBMX(Synonyms: 3-Isobutyl-1-methylxanthine, 1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methyl-xanthine), 10mM (in 1mL DMSO), CAS: 28822-58-4.
SDP

IBMX (CAS 28822-58-4) is a methylxanthine derivative commonly employed in research as a non-selective inhibitor of phosphodiesterase (PDE) isozymes It inhibits PDE3 PDE4 and PDE5 with IC50 values of approximately 6 5 26 3 and 31 7 M respectively By inhibiting PDE activity IBMX elevates intracellular cyclic AMP (cAMP) and cyclic GMP (cGMP) concentrations thereby activating downstream cyclic nucleotide-dependent protein kinases Additionally IBMX antagonizes adenosine receptors blocking endogenous adenosine-mediated cellular effects In animal studies IBMX administration has been shown to modulate drug-induced behavioral sensitization highlighting its utility in neuropharmacological research

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5

Apexbio Technology LLC IBMX(Synonyms: 3-Isobutyl-1-methylxanthine, 1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methyl-xanthine), 50mg, CAS: 28822-58-4.
SDP

IBMX (CAS 28822-58-4) is a methylxanthine derivative commonly employed in research as a non-selective inhibitor of phosphodiesterase (PDE) isozymes It inhibits PDE3 PDE4 and PDE5 with IC50 values of approximately 6 5 26 3 and 31 7 M respectively By inhibiting PDE activity IBMX elevates intracellular cyclic AMP (cAMP) and cyclic GMP (cGMP) concentrations thereby activating downstream cyclic nucleotide-dependent protein kinases Additionally IBMX antagonizes adenosine receptors blocking endogenous adenosine-mediated cellular effects In animal studies IBMX administration has been shown to modulate drug-induced behavioral sensitization highlighting its utility in neuropharmacological research

ENCOMPASS_PREFERRED