Lactams
Medchemexpress LLC Thalidomide-5-O-C14-NH2 hydrochloride | 97.7% | 522.08 g/mol | C27H40ClN3O5 | 10 MG
Thalidomide-5-O-C14-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied for research use in targeted protein degradation and PROTAC development. It is provided as a small-quantity, high-purity solid suitable for conjugation through linkers to build bifunctional degraders and other CRBN-recruiting constructs.
- High purity of 97.7%.
- Molecular weight 522.08 g/mol and chemical formula C27H40ClN3O5.
- White to off-white solid appearance.
- Storage recommendations: -20 °C; in solvent: -80 °C (6 months) or -20 °C (1 month), protect from light, store under nitrogen.
- Suitable for use as a CRBN-recruiting ligand in PROTAC synthesis.
![Medchemexpress LLC Butanoic acid, 4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl | 2308035-51-8 | 98.4% | 417.37 g/mol | C19H19N3O8 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244795.png-250.jpg)
Medchemexpress LLC Butanoic acid, 4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl | 2308035-51-8 | 98.4% | 417.37 g/mol | C19H19N3O8 | 1 G
Thalidomide-O-amido-C3-COOH is an E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a short carboxylic-acid linker for use in PROTAC design, synthesis, and degradation studies.
- Used as a cereblon E3 ligase ligand in PROTAC design and synthesis.
- High purity (98.4%) suitable for research applications.
- White to off-white solid with molecular weight 417.37 g/mol.
- Contains a carboxylic acid functional handle for conjugation chemistry.
- Available in small lab-scale quantities and supplied with a certificate of analysis.
Selleck Chemical LLC Brucine sulfate heptahydrate
Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons
Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | 99.9% | 332.27 | C15H12N2O7 | 25 G
Thalidomide-O-COOH is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiter in PROTAC and chemical biology research. It is supplied as a solid research reagent with high purity and characterized molecular properties for use in biochemical and cellular assays.
- High purity: 99.85%.
- Molecular formula: C15H12N2O7.
- Molecular weight: 332.27 g/mol.
- Appearance: solid, white to off-white.
- Available package sizes include 25 G for bulk research use.
- Intended use: cereblon recruitment and PROTAC design in research applications.
Medchemexpress LLC 14-3-3 epsilon Antibody (YA2629) | 100 UL
The 14-3-3 epsilon antibody (YA2629) is a rabbit-derived, non-conjugated IgG monoclonal antibody designed to target the 14-3-3 epsilon protein. This protein acts as an adapter involved in the regulation of diverse cellular signaling pathways by binding to phosphoserine or phosphothreonine motifs, thereby modulating the activity of binding partners. The antibody shows reactivity with human, mouse, and rat samples and is supplied as a liquid formulation.
- Reactivity with human, mouse, and rat samples
- Suitable for WB, IHC-P, ICC/IF, and FC applications
- Formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipping with blue ice
Medchemexpress LLC 14-3-3 epsilon antibody (YA2629) | 10 UL
This 14-3-3 epsilon antibody (YA2629) is a rabbit-derived, non-conjugated IgG monoclonal antibody that specifically targets the 14-3-3 epsilon protein. It is suitable for a diverse array of immunological applications.
- Host species: rabbit
- Reactivity: human, mouse, rat
- Conjugation: non-conjugated
- Predicted and observed molecular weight: 29 kDa
- Purity: affinity chromatography
- Storage: -20°C for 1 year; avoid repeated freeze/thaw cycles
- Appearance: liquid
- Applications include Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/Immunofluorescence (ICC/IF), and Flow Cytometry (FC)
- Formulation: rabbit IgG in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
- SwissProt ID: P62258
- Research field: neuroscience