DNA2 inhibitor C5 is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. It inhibits the nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2. It can be used in breast cancer and colorectal cancer research.
- Potent, competitive, and specific DNA2 nuclease inhibitor
- Inhibits nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2
- Useful in breast cancer and colorectal cancer research
- Shows strong synergistic effect in inhibiting MCF7 cell survival with MK4827