Lactones
Medchemexpress LLC IFN-gamma R1/CD119 10ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
![eMolecules 35501-83-8 | methyl trans-2-(hydroxymethyl)cyclopropanecarboxylate | Pharmablock260.286 | C12H20O6 | 97.000 | COC(=O)[C@H]1C[C@@H]1CO.COC(=O)[C@@H]1C[C@H]1CO | 1g | 551099119](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502159229.JPG-250.jpg)
eMolecules 35501-83-8 | methyl trans-2-(hydroxymethyl)cyclopropanecarboxylate | Pharmablock260.286 | C12H20O6 | 97.000 | COC(=O)[C@H]1C[C@@H]1CO.COC(=O)[C@@H]1C[C@H]1CO | 1g | 551099119
methyl trans-2-(hydroxymethyl)cyclopropanecarboxylate | Pharmablock | 35501-83-8260.286 | C12H20O6 | 97.000 | COC(=O)[C@H]1C[C@@H]1CO.COC(=O)[C@@H]1C[C@H]1CO | 1g | 551099119
Medchemexpress LLC IFN-gamma Mouse HE 5ug
IFN-gamma is a type II interferon family cytokine that participates in antiviral antibacterial and antitumor responses IFN-gamma Protein Mouse (HEK293 Fc) is the recombinant mouse-derived IFN-gamma protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC IFN-gamma Mouse HE 2ug
Recombinant mouse interferon-gamma (IFN-γ) produced in HEK293 mammalian cells. This tag-free, glycosylated cytokine is provided as a high-purity preparation characterized by SDS-PAGE and predicted molecular mass, and is intended for in vitro immunology and cell-signaling studies such as antiviral and macrophage-activation assays.
- Mammalian-expressed for native glycosylation.
- Tag free to avoid interference in receptor binding assays.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Predicted molecular mass 15.5 kDa; observed ~12-21 kDa due to glycosylation.
- Available in small research-appropriate aliquots (for example, 2 μg).
- Includes mature amino acid sequence for reproducibility.
- Suitable for cell signaling, immunology, and antiviral assays.
Medchemexpress LLC AMPK gamma 1 Antibody (YA621) | 38 kDa | 100 UL
This AMPK gamma 1 Antibody (YA621) is a rabbit-derived, non-conjugated IgG monoclonal antibody, targeting to AMPK gamma 1. It is formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA, with 0.01% Sodium azide as a preservative. This antibody is suitable for Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), and Immunoprecipitation (IP) applications, and has a concentration of 0.5 mg/mL. The predicted and observed molecular weight is 38 kDa. It is reactive with human samples.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets AMPK gamma 1
- Suitable for Western Blot, ICC/IF, and Immunoprecipitation
- Concentration of 0.5 mg/mL
- Predicted and observed molecular weight: 38 kDa
- Reactivity: Human
- Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Medchemexpress LLC Fc gamma RIIB/CD32b 50ug | 50ug
Fc RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin Fc region ITIM phosphorylated by Fc RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2 inhibits Ras activation down-regulates MAPK activity reduces PLC- function and results in PKC activation Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival Fc gamma RIIB/CD32b Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Fc gamma RIIIA/CD16a protein, rat | 5 UG
Recombinant rat Fc gamma RIIIA (CD16a) extracellular domain expressed in HEK293 cells with a C-terminal His tag. Supplied as a small, purified protein for receptor binding studies, antibody-dependent cellular cytotoxicity (ADCC) assays, and in vitro functional characterization.
- Rat extracellular domain expressed in HEK293 cells.
- C-terminal His tag for convenient detection and purification.
- Glycosylated to retain native binding properties.
- Suitable for binding assays and receptor characterization.
- Shipped frozen with recommended storage for long-term stability.
Medchemexpress LLC Interferon gamma receptor 1 (IFN-gamma R1) Fc-fusion protein | >95.0% | 5 UG
Recombinant human interferon-γ receptor 1 extracellular domain fused to a human Fc tag, expressed in HEK293 cells and supplied lyophilized for research use. The protein is intended for use in binding studies, biochemical characterization, and immunoassays requiring a soluble Fc-fusion receptor fragment.
- Recombinant extracellular domain of IFN-γ receptor 1 fused to hFc.
- Produced in HEK293 cells for human-like glycosylation.
- Purity >95% as determined by reducing SDS-PAGE.
- Molecular weight ~60-75 kDa.
- Lyophilized from 0.22 μm filtered PBS, pH 7.4 for stability.
- Recommended storage at -20°C; reconstituted stability at 4°C for 1 week.
- Suitable for binding assays and biochemical characterization.
![eMolecules 1147103-42-1 | (1S,3aR,6aS)-Ethyl octahydrocyclopenta[c]pyrrole-1-carboxylate hydrochloride | MFCD21606967 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502132320.JPG-250.jpg)
eMolecules 1147103-42-1 | (1S,3aR,6aS)-Ethyl octahydrocyclopenta[c]pyrrole-1-carboxylate hydrochloride | MFCD21606967 | 1g
Ambeed | 2-Bromo-5-(trifluoromethyl)thiazole | 100mg | 490561088 | A423755 | 1209458-80-9 | MFCD14702723 | 232.020 | C4HBrF3NS
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Medchemexpress LLC Gamma-secretase modulator 2 | 1093978-89-2 | 98.8% | C25H22F4N6O2 | 1 ML
Gamma-secretase modulator 2 is a potent and selective gamma-secretase modulator. It is used for the study of Alzheimer's disease and is intended for research use only.
- Potent and selective gamma-secretase modulator
- Appears as a solid
- Color is white to off-white
- Soluble in DMSO at 100 mg/mL
- Useful for research in neurological and neurodegenerative diseases
![eMolecules 39746-00-4 | Ambeed | (3aR4S5R6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate | 1g | 552610998 | A169100 | 276.288 | C15H16O5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502133688.JPG-250.jpg)
eMolecules 39746-00-4 | Ambeed | (3aR4S5R6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate | 1g | 552610998 | A169100 | 276.288 | C15H16O5
Medchem Express | PDE10-IN-5 | 5mg | 719836101 | HY-14550A | 898562-99-7 | 460.460 | C26H19F3N4O
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Medchemexpress LLC Gamma-glutamyl-arginine | 31106-03-3 | 97.7% | 303.31 | C11H21N5O5 | 10 MG
Gamma-glutamyl-arginine (L-γ-glutamyl-L-arginine) is a γ-glutamic acid-derived dipeptide isolated from Panax ginseng. Supplied as a purified research chemical (purity ~97.7%), it is intended for biochemical and natural product research and is provided with supporting documentation such as a certificate of analysis and a safety data sheet.
- Dipeptide structure: composed of γ-glutamic acid and arginine.
- High purity suitable for analytical and biochemical applications.
- Supplied in small quantities appropriate for research workflows.
- Documentation provided: COA and SDS for handling and quality verification.
- Molecular weight approximately 303.31 g/mol.
Medchemexpress LLC Recombinant human interferon gamma | 98059-61-1 | >95.0% | 500UG
Recombinant human interferon-gamma (IFN-γ) is a biologically active cytokine provided as a lyophilized protein for immunology and cell-signaling research. It corresponds to the mature human IFN-γ sequence (Q24-Q166), is expressed in E. coli, and is characterized for purity, activity, and low endotoxin for reliable experimental use.
- Biologically active recombinant human IFN-γ for cell signaling and immunology assays.
- Purity greater than 95% by reducing SDS-PAGE.
- Specific activity >1 x 10^6 units/mg; ED50 <1 ng/mL (HT-29 assay).
- Low endotoxin level: <1 EU/μg (LAL).
- Lyophilized formulation with stabilizers for improved shelf life.
- Expressed in E. coli; mature sequence Q24-Q166.
- Predicted mass ~16.7 kDa (≈16-18 kDa by SDS-PAGE).
- Store at -20°C; after reconstitution stable at 4°C for 1 week or frozen for long-term storage.
Medchemexpress LLC Fc gamma receptor IIa (CD32a) recombinant protein, rhesus macaque, C-terminal His tag | >95.0% | 100 UG
Recombinant extracellular fragment of rhesus macaque Fc gamma receptor IIa (CD32a), expressed in HEK293 cells and supplied with a C-terminal His tag. Provided lyophilized for use in binding and functional assays such as ELISA.
- Sequence range Q34-I217.
- Expression system HEK293 cells.
- Tag C-terminal His tag.
- Observed molecular weight ~25-35 kDa by SDS-PAGE.
- Purity >95% by reducing SDS-PAGE.
- Formulation lyophilized from PBS, pH 7.4.
- Recommended reconstitution concentration ≥100 μg/mL in ddH2O.
- Storage store at -20°C; after reconstitution 4°C for 1 week or -20°C long term; freeze aliquots for extended storage.