Lactones
Medchemexpress LLC Bd-1008 dihydrobromide | 138356-09-9 | 98.1% | 463.08 g/mol | C15H24Br2Cl2N2 | 25 MG
BD-1008 dihydrobromide is a research-grade sigma (σ) receptor antagonist used in neuropharmacology and addiction-related studies. It is commonly applied in receptor binding assays, dopamine microdialysis, and preclinical pharmacology to probe σ receptor function and dopaminergic signaling.
- High affinity for σ1 and σ2 receptors (Ki ≈ 2 nM and 8 nM).
- Low affinity for D2 receptor and dopamine transporter, reducing off-target effects.
- High purity (98.07%), suitable for research applications.
- Available in small research pack sizes, including 25 MG.
- Solid form with molecular weight of approximately 463.08 g/mol.
Medchemexpress LLC SIRP gamma Cynomolg 50ug | 50ug
SIRP gamma Protein a member of signal-regulatory protein (SIRP) family is the only SIRP detected on T cells and activated NK cells SIRP gamma can bind CD47 providing T cells and NK cells with a cell surface molecule capable of interacting with CD47 SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion SIRP gamma Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived SIRP gamma protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Fc gamma RIII/CD16 50ug | 50ug
The Fc RIIIA/CD16a protein is a receptor for IgG and is optimally activated upon binding of aggregated antigen-IgG complexes inducing antibody-dependent cellular cytotoxicity (ADCC) It mediates IgG effector function on natural killer cells limiting viral load Fc gamma RIII/CD16 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Ap-2 gamma/TFAP2C protein, human (His-tag) | >95.0% | 50 UG
Recombinant human AP-2 gamma (TFAP2C) protein fragment (L128-V223) expressed in E. coli with an N-terminal His tag. Supplied as a sterile lyophilized powder, this high-purity fragment is intended for biochemical assays, antibody validation, and protein-protein interaction studies focusing on the AP-2 gamma DNA-binding domain.
- Sequence-specific DNA-binding transcription factor fragment.
- N-terminal 10xHis tag for affinity purification.
- Purity >95% as determined by reducing SDS-PAGE.
- Molecular weight approximately 10-14 kDa.
- Do not reconstitute below 100 μg/mL in ddH2O.
- Store at -20°C; aliquot and freeze at -20°C or -80°C for long-term.
- Supplied as sterile lyophilized powder.