Oxazinanes
Cayman Chemical HA-1077 (hydrochloride), Purity: ≥98%, CAS: 203911-27-7, 50 mg
A potent inhibitor of ROCK2, PRK-2, MSK1, and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively; has been shown to reduce blood vessel constriction, decreases pulmonary arterial pressure, inhibit tumor angiogenesis, and improve insulin signaling in a diabetic rat model; drug forms are marketed for the treatment of pulmonary arterial hypertension and stable angina
Cayman Chemical CP 24,879 (hydrochloride), Purity: ≥98%, CAS: 10141-51-2, 1 mg
A Δ5/Δ6 desaturase inhibitor; reduces liver arachidonate content by ~50% in mice at 3 mg/kg; increases mead acid content and inhibits leukotriene C4 synthesis in murine mastocytoma cells at 5 µM
Sigma Aldrich Fine Chemicals Biosciences Aprepitant United States Pharmacopeia (USP) Reference Standard | 170729-80-3 | MFCD12912491 | 150MG
Aprepitant United States Pharmacopeia (USP) Reference Standard | Mol Wt: 534.43 | 170729-80-3 | MFCD12912491 | 150MG
Sigma Aldrich Fine Chemicals Biosciences Aprepitant >=98% (HPLC) | 170729-80-3 | MFCD12912491 | 25MG
Aprepitant >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 534.43 | 170729-80-3 | MFCD12912491 | 25MG
Medchemexpress LLC Chloroquine (dihydrochloride) | 3545-67-3 | MFCD06804666 | 99.6% | 392.79 g/mol | C18H28Cl3N3 | 10 MG
Chloroquine (dihydrochloride) is the dihydrochloride salt of chloroquine, a 4-aminoquinoline antimalarial and anti-inflammatory agent used as a research reagent. It is commonly used to inhibit autophagy, alter endosomal/lysosomal pH, and as a screening compound in antiviral and antiparasitic assays.
- High chemical purity suitable for research (reported ~99.6%).
- Solid form suitable for formulation or solution preparation.
- Commonly used as an autophagy inhibitor in cell biology experiments.
- Modulates endosomal and lysosomal pH for trafficking and uptake studies.
- Available in small pack sizes for screening and assay workflows.