Oxazinanes
TARGETMOL CHEMICALS INC CYTARABINE HYDROCHLORIDE 50MG
Also available in 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV. purity: 99%
eMolecules 212127-80-5 | 2-(2,5-Dihydro-3-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | Synthonix - Stock | MFCD16996209 | 196.050 | C10H17BO3 | 95.000 | CC1(C)OB(OC1(C)C)C1=CCOC1 | 5g | 525914657
2-(2,5-Dihydro-3-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | Synthonix - Stock | 212127-80-5 | MFCD16996209 | 196.050 | C10H17BO3 | 95.000 | CC1(C)OB(OC1(C)C)C1=CCOC1 | 5g | 525914657
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.35% | 50 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative used in bronchiectasis research. This product is strictly for research purposes and not for sale to patients.
- Suitable for bronchiectasis research
- Powder storage: -20°C for 3 years, or 4°C for 2 years
- Storage in solvent: -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC Inolitazone dihydrochloride | 223132-38-5 | >98.45% | 575.51 | 50 MG
Inolitazone dihydrochloride | 223132-38-5 | >98.45% | 575.51 | 50 MG
Medchemexpress LLC CI-966 hydrochloride | 110283-66-4 | 509.87 g/mol | C23H22ClF6NO3 | 1 ML
CI-966 hydrochloride is a selective inhibitor of the GABA transporter GAT-1 used as a research reagent for in vitro and in vivo studies of GABAergic signaling. It is the hydrochloride salt and has reported potency at human and rat GAT-1.
- Selective inhibitor of GAT-1 with reported IC50s of 0.26 μM (hGAT-1) and 1.2 μM (rGAT-1).
- Orally active and brain-penetrant, useful for neuropharmacology studies.
- Soluble in DMSO; clear solutions at reported concentrations.
- Typical handling: solid stored at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (short term).
Medchemexpress LLC ML-7 hydrochloride | 110448-33-4 | C15H18ClIN2O2S | 25 MG
ML-7 hydrochloride is a naphthalene sulphonamide derivative that potently inhibits Myosin Light Chain Kinase (MLCK) with an IC₅₀ of 300 nM, and also inhibits YAP/TAZ. This product is intended for research use only.
- Potently inhibits Myosin Light Chain Kinase (MLCK) with an IC₅₀ of 300 nM.
- Inhibits YAP/TAZ.
- Inhibits rabbit portal vein α1-adrenoceptor NSCC with an IC₅₀ of 0.8 μM.
- Attenuates Dexmedetomidine (DMT)-induced contraction.
- Reduces intracerebral Evans Blue extravasation, suggesting a reduction in brain edema.
- Reduces brain water content and improves neurological function after controlled cortical impact (CCI).
- Significantly reduces the protein level of phosphorylated MLC2 and the phosphorylation ratio of MLC2 in BMECs.
- Directly inhibits the expression of ZO-1.
Apexbio Technology LLC Sarpogrelate hydrochloride 135159-51-2 10mM (in 1mL DMSO)
Sarpogrelate hydrochloride (CAS 135159-51-2) is a selective antagonist of the 5-HT2A receptor exhibiting a binding affinity (Ki) of 8 39 nM comparable to ritanserin By inhibiting 5-HT2A receptor-mediated pathways sarpogrelate suppresses platelet aggregation thrombus formation and vascular smooth muscle cell proliferation In vitro its primary metabolite (M-1) blocks 5-HT-induced responses at the 5-HT2A receptor with minimal stereoselective difference Clinically oral administration of sarpogrelate in patients with peripheral arterial disease significantly enhances forearm and leg blood flow responses to reactive hyperemia indicating improved vascular function Sarpogrelate is employed in research on platelet function thrombosis and vascular disorders
TARGETMOL CHEMICALS INC 9-dihydro-13-acetylbaccatin II
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 9-dihydro-13-acetylbaccatin III (9-DHAB III)is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR. Purity 98.96%
TARGETMOL CHEMICALS INC CGS 21680 HYDROCHLORIDE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM) an adenosine receptor agonist exhibits 140-fold potency in A2 receptor over A1 receptor. purity: 98%
Medchemexpress LLC 8-Azaadenine | 1123-54-2 | 99.9% | 136.12 | 250 MG
8-Azaadenine is an inhibitor of Xanthine Oxidase with an IC50 of 0.54 μM and a Ki of 0.66 μM. It is produced via the metabolism of 8-Azaadenosine and can be incorporated into polynucleotide chains alongside 8-Azaguanine to impact purine metabolism. This product is used in cancer studies and can also be synthesized into various derivatives through alkylation reactions, which demonstrate antiviral activity.
- Inhibits Xanthine Oxidase with an IC50 of 0.54 μM and a Kᵢ of 0.66 μM
- Produced via the metabolism of 8-Azaadenosine
- Incorporated into polynucleotide chains to affect purine metabolism
- Used in the study of cancer
- Can be synthesized into derivatives with antiviral activity
Medchemexpress LLC A-7 hydrochloride (Ophobolin A) | 79127-24-5 | MFCD00058400 | 99.1% | 433.44 g/mol | C20H30Cl2N2O2S | 5 MG
A-7 hydrochloride (Ophobolin A) is the hydrochloride salt of a fungal sesterterpenoid that functions as a calmodulin antagonist and is used as a biochemical tool in cancer and calmodulin-related research.
- Acts as a calmodulin antagonist in biochemical assays.
- Useful for cancer-related cellular and molecular studies.
- Provided as a solid, light yellow to yellow substance.
- High reported purity (99.1%).
- Supplied in small milligram quantities suitable for lab-scale experiments.
- For research use only; not intended for clinical or human use.
Selleck Chemical LLC Cyproheptadine hydrochloride sesquihydrate S4635-500mg
Cyproheptadine hydrochloride (Periactin Peritol) is non-selective 5HT2 antagonist with IC50 of 0 6 nM Also a SETD7/9 inhibitor
TARGETMOL CHEMICALS INC Orphenadrine hydrochloride
Also available in 1 g, 1 mL, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. Purity 99.54%
Medchemexpress LLC Pramipexole dihydrochloride | 104632-25-9 | 99.7% | 284.25 | 1 ML
Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist. It can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS).
- Selective dopamine D2-type receptor agonist
- BBB penetrant
- Useful for research into Parkinson's disease (PD) and restless legs syndrome (RLS)
- Cytoprotective properties
- Reduces infarction volume
- Improves neurological recovery
- Prevents ischemic cell death
Medchemexpress LLC N1,N1-Dimethylpropane-1,2-diamine dihydrochloride | 75975-34-7 | 96.0% | 175.10 | 500 MG
N1,N1-Dimethylpropane-1,2-diamine dihydrochloride is a drug intermediate for the synthesis of various active compounds.