Oxazinanes
Accela Chembio Inc 3 | 4-DIHYDRO-2H-1 | 4-BENZOXAZINE | 5G | 5735-53-5 | MFCD02181098 | 97+% | RETEST PERIOD: 540DAYS | LIGHT SENSITIVE/AIR SENSITIVE/+4c
3 | 4-DIHYDRO-2H-1 | 4-BENZOXAZINE | 5G | 5735-53-5 | MFCD02181098 | 97+% | RETEST PERIOD: 540DAYS | LIGHT SENSITIVE/AIR SENSITIVE/+4c
Medchemexpress LLC Inolitazone dihydrochloride | 223132-38-5 | 98.5% | 575.51 | 100 MG
Inolitazone dihydrochloride is a novel high-affinity PPARγ agonist, demonstrating potent anti-proliferative activities both in vitro and in vivo, with an IC50 of 0.8 nM for growth inhibition. Its biological activity is dependent on PPARγ.
- Upregulates the cell cycle kinase inhibitor p21WAF1/CIP1
- Activates PPARγ:RXRα-dependent transcription at 10 nM
- Specifically activates PPARγ, unlike PPARα or PPARδ
- Exhibits a low EC50 of 1 nM for activating PPARγ in DRO cells
- Potently inhibits growth with an IC50 of 0.8 nM
- Shows additive antiproliferative activity when combined with paclitaxel
- Inhibits tumor growth in a dose-responsive manner in vivo, including established DRO and ARO tumors
Cayman Chemical MethylLNIO hydrochloride
A competitive NOS inhibitor; more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM)
TARGETMOL CHEMICALS INC MIDODRINE HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Midodrine is converted to its active metabolite desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine hydrochloride (Pro-Amatine) is the hydrochloride salt form of midodrine a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. purity: 99%
TARGETMOL CHEMICALS INC LY-294002 HYDROCHLORIDE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3K(alpha)/(delta)/(beta) (IC50 0.5/0.57/0.97 uM in cell-free assays); more stable than Wortmannin in solution and also is a blocker of autophagosome formation. purity: 99%
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 100 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative that can be used for bronchiectasis research.
- Can be used for bronchiectasis research
- Exhibits cytotoxicity against human A375 cells (IC50: 39 μM) and human MRC5 cells (IC50: 47 μM)
- Recommended storage temperature for powder is -20°C for 3 years and 4°C for 2 years
- Recommended storage temperature for in solvent is -80°C for 6 months and -20°C for 1 month
Medchemexpress LLC CN128 hydrochloride | 1335282-05-7 | 98.2% | 250 MG
CN128 hydrochloride (CN328) is an orally active and selective iron chelator primarily used in the research of β-thalassemia. It demonstrates high selectivity for iron(III) over other metals and has been shown to lack genetic toxicity.
- Orally active and selective iron chelator
- Used for research of β-thalassemia
- Exhibits high selectivity for iron(III) over other metals
- Lacks genetic toxicity
- Demonstrates good oral bioavailability (82.6%) in rats
- Well-tolerated in rats with no mortality at higher dose levels
- Shows good iron scavenging efficacy in rats
Medchemexpress LLC 2,5(1H,6H)-quinolinedione, 7,8-dihydro | 15450-69-8 | MFCD00766821 | 99.9% | 163.17 g/mol | C9H9NO2 | 10 G
7,8-Dihydro-2,5(1H,6H)-quinolinedione (compound SF32) is a research-grade small molecule described in literature as a positive inotropic agent. It is supplied as a solid with high analytical purity and intended for laboratory research applications; refer to the manufacturer documentation and certificate of analysis for handling, storage, and stability details.
- High reported purity: 99.86%.
- Solid form; appearance light brown to light yellow.
- Stable under recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Solvent storage guidance: -80°C for 6 months, -20°C for 1 month.
- Suitable for in vitro research as a positive inotropic agent.
- Available in multiple pack sizes for laboratory use.
- Supplied with a certificate of analysis for quality verification.
eMolecules 7778-42-9 | Sulfamoyl chloride | Oakwood Chemical | MFCD11519990 | 115.530 | ClH2NO2S | 95.000 | NS(Cl)(=O)=O | 250mg | 806975989
Sulfamoyl chloride | Oakwood Chemical | 7778-42-9 | MFCD11519990 | 115.530 | ClH2NO2S | 95.000 | NS(Cl)(=O)=O | 250mg | 806975989
eMolecules 121492-06-6 | N-Boc-N-methylethylenediamine | Ambeed | MFCD01317789 | 174.244 | C8H18N2O2 | 98.000 | CN(CCN)C(=O)OC(C)(C)C | 25g | 552722211
N-Boc-N-methylethylenediamine | Ambeed | 121492-06-6 | MFCD01317789 | 174.244 | C8H18N2O2 | 98.000 | CN(CCN)C(=O)OC(C)(C)C | 25g | 552722211
eMolecules 81893-75-6 | 4-(Methylamino)butanoic acid ethyl ester HCl | Acrotein ChemBio Inc. | MFCD17215565 | 181.660 | C7H16ClNO2 | 97.000 | Cl.CCOC(=O)CCCNC | 1g | 705837559
4-(Methylamino)butanoic acid ethyl ester HCl | Acrotein ChemBio Inc. | 81893-75-6 | MFCD17215565 | 181.660 | C7H16ClNO2 | 97.000 | Cl.CCOC(=O)CCCNC | 1g | 705837559
TARGETMOL CHEMICALS INC K145 HYDROCHLORIDE 50MG
Also available in 5 mg 10 mg 25 mg and bulk. Please contact Fisher for quotes. K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity. purity: 99%
TARGETMOL CHEMICALS INC KL-11743 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KL-11743 specifically blocks glucose metabolism triggering an acute collapse in NADH pools and a striking accumulation of aspartate indicating a dramatic shift toward oxidative phosphorylation in the mitochondria. purity: 98%
TARGETMOL CHEMICALS INC THEODRENALINE HYDROCHLOR 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia. purity: 99%
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly