Oxazinanes
Cayman Chemical PIK-75, Purity: ≥98%, CAS: 372196-67-3, 1 mg
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
Cayman Chemical GW 3965 (hydrochloride), Purity: ≥98%, CAS: 405911-17-3, 5 mg
An orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively; alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism
AdipoGen 5-DTAF hydrochloride
Chemical. CAS 21811-74-5. Formula C23H12Cl2N4O5 . HCl. MW 495.3 . 36.5. Synthetic. 5-DTAF is highly reactive with proteins. Unlike other reactive fluoresceins, 5-DTAF not only reacts with amino groups, but also reacts with thiol groups and even directly reacts with hydroxy groups such as polysaccharides and other alcohols in aqueous solution at pH above 9. Due to its high reactivity, 5-DTAF is also used to label carbohydrates. Spectral properties Abs/Em = 492/517 nm
AdipoGen N-2-Aminoethylbiotinamid HCl
Chemical. CAS 111822-45-8. Formula C12H23ClN4O2S. MW 322.85. Synthetic. Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.