Oxazinanes
Medchemexpress LLC Amtb hydrochloride | 926023-82-7 | >98.0% | 430.99 | C23H27ClN2O2S | 1 ML
AMTB hydrochloride is a small-molecule TRPM8 channel blocker used in laboratory pharmacology and ion channel research. It has been applied in studies of overactive bladder and painful bladder syndrome and is reported to affect voltage-gated sodium channels in some assays.
- Selective TRPM8 channel blocker for ion channel studies.
- Reported activity in research on overactive bladder and painful bladder syndrome.
- Also inhibits voltage-gated sodium channels in some assays.
- Soluble in DMSO; manufacturer provides stock solution preparation for concentrations such as 10 mM.
- High purity available (≥98% by HPLC) and characterized by molecular weight 430.99.
Apexbio Technology LLC AMTB hydrochloride 1mg
AMTB hydrochloride (CAS 926023-82-7) is a selective antagonist of the TRPM8 ion channel effectively inhibiting TRPM8-mediated activation induced by agonists such as icilin with a reported pIC50 of approximately 6 23 In addition to its primary action AMTB hydrochloride also exhibits non-selective inhibitory effects on voltage-gated sodium channels (NaV) This compound is commonly utilized in biomedical research to investigate the role of TRPM8 channel activity alterations in the pathophysiology of bladder overactivity and bladder pain syndrome