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Quercetin-3'-O-glucoside is an orally active flavonoid glycoside with significant biological activities. It reduces liver glucose-6-phosphatase and regulates antioxidant enzyme activities. This compound inhibits DNA topoisomerase II and induces S-phase cell cycle arrest and apoptosis in hepatocellular carcinoma cells. It also inhibits EGFR-mediated signaling pathways and growth factor-induced migration in pancreatic cancer cells, alongside its free radical scavenging effects.
Reduces liver glucose-6-phosphatase activity
Regulates antioxidant enzyme activities
Inhibits DNA topoisomerase II
Induces S-phase cell cycle arrest and apoptosis in hepatocellular carcinoma cells
Inhibits EGFR-mediated signaling pathways
Exerts free radical scavenging effects
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