Piperazines

Aobchem 2-Bromo-4-(1 1-dimethylpropyl)phenol | ≥97% | CAS 18966-64-8 | C11H15BrO | 250mg

2-Bromo-4-(1 1-dimethylpropyl)phenol | ≥97% | CAS 18966-64-8 | C11H15BrO | 250mg

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Medchemexpress LLC Jak1-in-8 | 1973485-18-5 | 95.0% | 442.51 | 100 MG

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JAK1-IN-8 is a potent JAK1 inhibitor (IC50<500 nM), identified as compound 28, and extracted from patent WO2016119700A1. It targets JAK1 with high potency and has varying inhibitory effects on JAK2 and JAK3.

• Potent JAK1 inhibitor with IC50 <500 nM
• Targets JAK2 with IC50 between 500-1000 nM
• Targets JAK3 with IC50 >5000 nM

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Medchemexpress LLC L-Aspartyl-L-phenylalanine | 13433-09-5 | 98.0% | 280.28 | 1 ML

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L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM. It is suitable for laboratory research applications.

• Inhibits angiotensin converting enzyme (ACE)
• Metabolite of aspartame
• Suitable for research use only

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Medchemexpress LLC Dexrazoxane (hydrochloride) | 149003-01-0 | 99.83% | C11H18Cl2N4O4 | 1 ML

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Dexrazoxane hydrochloride, also known as ICRF-187 hydrochloride, is a heart protectant that helps preserve ovarian function and fertility. It exhibits antioxidant and anti-inflammatory properties, can cross the blood-brain barrier, and offers neuroprotective effects for neurodegenerative disease studies. Functioning as an iron chelator, it reduces anthracycline-induced cardiotoxicity by decreasing the formation of superoxide radicals.

• Preserves ovarian function and fertility.
• Possesses antioxidant and anti-inflammatory properties.
• Crosses the blood-brain barrier.
• Improves motor function disorders.
• Offers neuroprotective effects.
• Chelates iron to reduce cardiotoxicity from anthracyclines.
• Induces DNA breaks and apoptosis in human fibrosarcoma cell lines.
• Protects ovarian cells from DXR-induced DNA damage.

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Apexbio Technology LLC Dexrazoxane 24584-09-6 10mg

Dexrazoxane is a cell-permeable iron chelator that suppresses intracellular superoxide radical generation via iron sequestration thereby exhibiting antioxidant activity Dexrazoxane exerts its biological effects primarily by modulating oxidative stress and ferroptosis pathways In cell-based studies including myocardial H9c2 cell models dexrazoxane inhibits ferroptosis by suppressing the HMGB1 pathway and induces DNA damage and apoptosis in various tumor cell lines Based on these pharmacological properties dexrazoxane holds research potential in the study of cardioprotective mechanisms tumor-related DNA damage responses ferroptosis and oxidative stress processes

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Medchemexpress LLC HY-14444 5mg Medchemexpress, Plinabulin CAS:714272-27-2 Purity:>98%

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Medchemexpress, HY-14444 5mg Plinabulin CAS:714272-27-2 Plinabulin (NPI-2358) is a vascular disrupting agen ( VDA ) against tubulin-depolymerizing with an IC 50 of 9.8 nM against HT-29 cells [1] . Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC Dexrazoxane | 50MG

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Dexrazoxane | 50MG

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Medchemexpress LLC HY-107091 5mg Medchemexpress, Aspartyl-alanyl-diketopiperazine CAS:110954-19-3 Purity:>98%

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Medchemexpress, HY-107091 5mg Aspartyl-alanyl-diketopiperazine CAS:110954-19-3 Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC Aspartyl-alanyl-diketopiperazine | 110954-19-3 | 98.9% | 186.17 g/mol | C7H10N2O4 | 1 ML

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Aspartyl-alanyl-diketopiperazine (DA-DKP) is a cyclic dipeptide derived from the N-terminus of human albumin with reported immunomodulatory activity. It modulates inflammatory immune responses and is supplied for laboratory research as a solid or as a ready-to-use solution.

• Purity 98.87%.
• Molecular weight 186.17 g/mol.
• Chemical formula C7H10N2O4.
• CAS number 110954-19-3.
• Physical form solid, white to off-white.
• Also available as a 10 mM solution in DMSO, 1 mL.
• Typical solid package sizes 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
• For research use only; not for human or clinical use.

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Sigma Aldrich Fine Chemicals Biosciences Dexrazoxane >=95% (HPLC) | 24584-09-6 | MFCD00866449 | 25MG

Dexrazoxane >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 268.27 | 24584-09-6 | MFCD00866449 | 25MG

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Medchemexpress LLC L-Aspartyl-L-phenylalanine | 13433-09-5 | 98.0% | 280.28 | 500 MG

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L-Aspartyl-L-phenylalanine is a metabolite of aspartame. It functions as an inhibitor of angiotensin converting enzyme (ACE), demonstrating a Ki of 11 μM against ACE purified from rabbit lungs.

• Metabolite of aspartame.
• Functions as an ACE inhibitor.
• Ki of 11 μM against ACE purified from rabbit lungs.
• Appearance: Solid, white to off-white.
• Shipping at room temperature (continental US).
• Storage for powder: -20°C for 3 years, 4°C for 2 years.
• Storage in solvent: -80°C for 6 months, -20°C for 1 month.

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Aobchem 4-Bromo-1-fluoro-2-(piperidinomethyl)benzene | ≥97% | CAS 1345471-85-3 | C12H15BrFN | 250mg

4-Bromo-1-fluoro-2-(piperidinomethyl)benzene | ≥97% | CAS 1345471-85-3 | C12H15BrFN | 250mg

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Aobchem 1-(4-(2-Hydroxyethoxy)phenyl)ethanone | ≥97% | CAS 31769-45-6 | C10H12O3 | 1g

1-(4-(2-Hydroxyethoxy)phenyl)ethanone | ≥97% | CAS 31769-45-6 | C10H12O3 | 1g

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Aobchem 4-Bromo-1-fluoro-2-(piperidinomethyl)benzene | ≥97% | CAS 1345471-85-3 | C12H15BrFN | 500mg

4-Bromo-1-fluoro-2-(piperidinomethyl)benzene | ≥97% | CAS 1345471-85-3 | C12H15BrFN | 500mg

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Aobchem (3-Bromo-5-fluorophenyl)(morpholino)methanone | ≥97% | CAS 1329457-16-0 | C11H11BrFNO2 | 1g

(3-Bromo-5-fluorophenyl)(morpholino)methanone | ≥97% | CAS 1329457-16-0 | C11H11BrFNO2 | 1g

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