Piperazines
![1,1'-(Decane-1,10-diyl)bis[4-aza-1-azoniabicyclo[2.2.2]octane] Dibromide 95.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-94630-53-2.jpg-250.jpg)
1,1'-(Decane-1,10-diyl)bis[4-aza-1-azoniabicyclo[2.2.2]octane] Dibromide 95.0+%, TCI America™
CAS: 94630-53-2 Molecular Formula: C22H44Br2N4 Molecular Weight (g/mol): 524.43 InChI Key: YTGWJQLFKYWCCF-UHFFFAOYSA-L Synonym: 1,10-Bis[4-aza-1-azoniabicyclo[2.2.2]octan-1-yl]decane Dibromide PubChem CID: 44629777 IUPAC Name: 4-[10-(1-aza-4-azoniabicyclo[2.2.2]octan-4-yl)decyl]-1-aza-4-azoniabicyclo[2.2.2]octane;dibromide SMILES: C1C[N+]2(CCN1CC2)CCCCCCCCCC[N+]34CCN(CC3)CC4.[Br-].[Br-]
Medchemexpress LLC 1-(chlorocarbonyl)piperidine-d10 | 1219803-31-2 | >98.0% | 10 MG
1-(Chlorocarbonyl)piperidine-d10 is a deuterium-labeled form of 1-(chlorocarbonyl)piperidine intended for use as an isotope-labeled tracer or internal standard in analytical, pharmacokinetic, and drug metabolism studies. The compound is a small-quantity solid with formula C6D10ClNO, molecular weight 157.66, and CAS 1219803-31-2, provided for research and analytical applications.
- Deuterium-labeled tracer for quantitative mass spectrometry.
- Provides a defined d10 isotopic shift for internal standardization.
- Supplied as a small-quantity solid suitable for analytical workflows.
- Useful in ADME and metabolic profiling applications.
- Handle and store according to SDS recommendations for acid chloride derivatives.
Medchemexpress LLC 7-(2-aminoethyl)camptothecin TFA | 99.6% | 505.44 g/mol | C24H22F3N3O6 | 10 MG
7-(2-aminoethyl)camptothecin TFA is the trifluoroacetic acid salt of a camptothecin derivative used as a research reagent and synthetic intermediate for preparing triple-helix-forming oligonucleotide-camptothecin (TFO-CPT) conjugates and for DNA cleavage studies.
- High purity: 99.6% as supplied.
- Molecular weight 505.44 g/mol; formula C24H22F3N3O6.
- Solid form, soluble in DMSO for stock solutions.
- Available in small research quantities such as 10 MG for synthesis and analytical work.
Medchemexpress LLC Carm1 degrader-1 hydrochloride | 3032785-00-2 | 99.4% | 1316.14 | C71H99ClN12O8S | 10 MG
CARM1 degrader-1 hydrochloride is a proteolysis-targeting chimera (PROTAC) that induces VHL- and proteasome-dependent degradation of co-activator associated arginine methyltransferase 1 (CARM1). It has a reported DC50 of 8.1 nM and inhibits methylation of CARM1 substrates, which has been shown to reduce breast cancer cell migration. The compound is provided as a hydrochloride salt and is characterized by a high reported purity for research use.
- Potent PROTAC degrader of CARM1 with a low nanomolar DC50.
- Acts through VHL- and proteasome-dependent degradation pathways.
- Reduces methylation of CARM1 substrates such as PABP1 and BAF155.
- Demonstrated effect on breast cancer cell migration in preclinical assays.
- Provided as a hydrochloride salt with high reported purity.
- Available in small research quantities suitable for in vitro studies.
Medchemexpress LLC Bibf 1202 | 894783-71-2 | MFCD28167767 | 99.8% | 525.60 g/mol | C30H31N5O4 | 10 MG
BIBF 1202 is the carboxylate metabolite of nintedanib and a VEGFR2 kinase inhibitor (reported IC50 ≈ 62 nM). Supplied as a powder for research use, it is intended for kinase inhibition assays, metabolite and ADME studies, and target validation.
- Carboxylate metabolite of nintedanib with VEGFR2 inhibitory activity (IC50 ≈ 62 nM).
- High purity (reported 99.82%).
- Molecular weight 525.60 g/mol; formula C30H31N5O4.
- Soluble in DMSO at ≥ 45 mg/mL.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years).
- Supplied in small research quantities suitable for in vitro and in vivo studies.
Medchemexpress LLC 3'-O-(2-methoxyethyl)adenosine | 303197-30-0 | 99.9% | 325.32 g·mol⁻¹ | C13H19N5O5 | 10 MG
3'-O-(2-methoxyethyl)adenosine is a nucleoside analogue used in biochemical and medicinal chemistry research. It is provided as a high-purity solid in small milligram quantities for laboratory experiments, including studies of nucleoside metabolism, oligonucleotide modification, and structure-activity relationships.
- High purity (~99.9%) suitable for analytical and biochemical work.
- Available in small research pack sizes (5 mg-200 mg).
- Molecular formula C13H19N5O5; molecular weight 325.32 g·mol⁻¹.
- CAS number 303197-30-0 for unambiguous identification.
- Supplied as a stable solid for low-temperature storage and handling.
Medchemexpress LLC 2-(ethoxycarbonyl)-3-methylbutanoic acid | 15112-52-4 | 174.19 g/mol | C8H14O4 | 10 MG
2-(Ethoxycarbonyl)-3-methylbutanoic acid is a small-molecule organic intermediate used in the synthesis of active pharmaceutical compounds and research chemicals. It is intended for laboratory research use only and is offered in small pack sizes suitable for synthetic chemistry and method development.
- Used as a drug intermediate in organic synthesis.
- Suitable for method development and small-scale synthesis.
- Molecular formula C8H14O4; molecular weight 174.19 g/mol.
- Purity documentation is available from the supplier.
Medchemexpress LLC 6-(2-hydroxyethoxy)-1-hexanol | 23684-16-4 | 95.0% | 162.23 g/mol | C8H18O3 | 10 MG
6-(2-Hydroxyethoxy)-1-hexanol is an organic intermediate used in medicinal chemistry for the synthesis of various active pharmaceutical compounds. It is supplied as a light brown oily substance, typically at 95.0% purity, and requires low-temperature storage to preserve stability.
- Used as a drug intermediate in synthesis workflows.
- Typical purity 95.0% as supplied.
- Oily appearance, light brown to brown.
- Molecular weight 162.23 g/mol; molecular formula C8H18O3.
- Store frozen or refrigerated to maintain stability.
- Available in small milligram pack sizes for research use.
Medchemexpress LLC 3-O-(2-aminoethyl)-25-hydroxyvitamin D3 | 163018-26-6 | MFCD22572728 | 99.3% | 457.73 | C30H51NO2 | 10 MG
3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a synthetic derivative of 25-hydroxyvitamin D3 used as a vitamin D receptor (VDR) ligand in biomedical research. It is supplied as a high-purity solid for laboratory research; solutions are unstable and should be freshly prepared.
- High purity (≈99.3%).
- Acts as a ligand for the vitamin D receptor (VDR).
- Supplied as a solid suitable for in vitro and in vivo studies.
- Stable as a solid; unstable in solution-prepare solutions fresh.
- Store at 4°C, protect from light, under inert atmosphere.
- Use freshly opened DMSO to improve solubility for protocols.
![Medchemexpress LLC 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin- | 955977-50-1 | 99.0% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233789.png-250.jpg)
Medchemexpress LLC 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin- | 955977-50-1 | 99.0% | 10 MG
PI-3065 is a selective small-molecule inhibitor of the PI3K p110δ isoform with potent biochemical inhibition and characterized isoform selectivity. It is supplied as a powder for research use.
- Potent inhibition of PI3K p110δ (IC50 5 nM; Ki 1.5 nM).
- Markedly reduced activity against p110α, p110β, and p110γ (IC50s 910 nM, 600 nM, >10,000 nM).
- Provided as a powder in 10 MG quantities.
- Powder storage: stable at -20°C (3 years) and 4°C (2 years) when stored as recommended.
- Demonstrated activity in cellular and in vivo models consistent with p110δ targeting.
Sigma Aldrich 2-Ethyl-9,10-dimethoxyanthracene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC 2'-O-(2-methoxyethyl)-cytidine | 223777-16-0 | 100.0% | 301.30 g/mol | C12H19N3O6 | 1 ML
2'-O-(2-methoxyethyl)-cytidine is a chemically modified cytidine nucleoside provided for research use and supplied as a 10 mM solution in DMSO or as solid material in multiple sizes. It is used as a nucleoside analog and an oligonucleotide building block in biochemical and cellular studies.
- modified cytidine nucleoside
- supplied as 10 mM solution in DMSO or solid material
- high reported purity suitable for research applications
- used as a nucleoside analog in biochemical studies
- available in multiple solid sizes for synthetic or analytical needs
Medchemexpress LLC 2'-O-(2-methoxyethyl)-uridine | 223777-15-9 | MFCD17215636 | 99.2% | 302.28 g/mol | C12H18N2O7 | 1 ML
2'-O-(2-methoxyethyl)-uridine is a chemically modified nucleoside derived from uridine and supplied for research applications. It is available as a 10 mM solution in DMSO (1 mL) and in solid quantities, and is characterized for purity and solubility to support nucleic acid chemistry and therapeutic development research.
- Chemically modified uridine nucleoside.
- Purity 99.2% as specified by supplier.
- Available as 10 mM solution in DMSO (1 mL) and as solid quantities for experimental flexibility.
- Soluble in DMSO; manufacturer lists in vivo formulation protocols and storage guidance.
- Intended for research use only.
TARGETMOL CHEMICALS INC MRT68921 dihydrochloride 25MG
Also available in 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively). Purity 98.98%
TARGETMOL CHEMICALS INC K-604 dihydrochloride 5MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. K-604 dihydrochloride, a potent and selective acyl-CoAcholesterol acyltransferase 1 inhibitor, exhibits an IC50 of 0.45±0.06 uM. Purity 99.88%
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