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Piperazinoazepines

Organic heterocyclic compounds that consist of an azepine ring and a piperazine ring connected by a carbon-nitrogen bridge; piperazine is a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions in the ring.

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1

Med Vet International Mirtazapine Tablets, 7.5mg, 30ct.

VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED

Mirtazapine is a generic version of Remeron. It is an antidepressant that may be used to help treat major depressive disorder.

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2

Medchemexpress LLC Mianserin | 24219-97-4 | 99.42% | 25 MG
SDP

Mianserin is an orally active H1 receptor antagonist that can also activate κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. Mianserin modulates social and exploratory behavior and raises electroconvulsive thresholds. It is used in the research of neurological diseases such as depression and epilepsy.

  • Orally active H1 receptor antagonist
  • Activates κ-opioid receptor and octopamine receptor
  • Increases ERK1/2 and CREB phosphorylation
  • Antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation
  • Modulates social and exploratory behavior
  • Raises electroconvulsive thresholds
  • Useful for research into neurological diseases like depression and epilepsy

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3

Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 500 MG
SDP

Mianserin hydrochloride is an orally active H1 receptor antagonist and can activate κ-opioid receptor and octopamine receptor. It can be used for the research of neurological diseases such as depression and epilepsy.

  • Solid appearance
  • Melting/freezing point >230°C
  • Stable under recommended storage conditions
  • Increases ERK1/2 and CREB phosphorylation
  • Modulates social and exploratory behavior
  • Raises electroconvulsive thresholds

ENCOMPASS_PREFERRED
4

Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 200 MG
SDP

Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Its metabolism is primarily handled by cytochrome P450 isoenzymes CYP1A2, CYP2D6, and CYP3A4.

  • Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
  • Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
  • Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
  • Inhibits Con A-induced liver injury by suppressing hepatic macrophage/monocyte activation

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