Piperidines

Medchemexpress LLC JNJ-1013 | 2597343-08-1 | 99.8% | 878.05 g/mol | C46H55N9O7S | 10 MG

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JNJ-1013 is a research-grade PROTAC degrader that selectively targets interleukin-1 receptor-associated kinase 1 (IRAK1). It induces IRAK1 degradation, modulates downstream signaling, and has been characterized in cellular assays for apoptosis and pathway inhibition. Supplied as a high-purity solid, it is intended for in vitro biochemical and cellular studies.

• Potent IRAK1 activity with reported IC50 values: 72 nM (IRAK1), 443 nM (IRAK4), 1,071 nM (VHL FP).
• High reported purity (99.8%).
• Molecular weight 878.05 g/mol; formula C46H55N9O7S.
• Soluble in DMSO at 25 mg/mL; may require warming or sonication.
• Recommended storage: protect from light at 4°C; in solution store at -80°C for long-term or -20°C up to one month.
• Suitable for in vitro target validation, signaling pathway studies, and apoptosis assays.

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eMolecules​ 138007-24-6 | tert-Butyl 4-Piperidinecarboxylate | Accela ChemBio | MFCD02684429 | 185.267 | C10H19NO2 | 98.000 | CC(C)(C)OC(=O)C1CCNCC1 | 10g | 796984131

tert-Butyl 4-Piperidinecarboxylate | Accela ChemBio | 138007-24-6 | MFCD02684429 | 185.267 | C10H19NO2 | 98.000 | CC(C)(C)OC(=O)C1CCNCC1 | 10g | 796984131

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eMolecules​ 4-HYDROXYPIPERIDINE 100G

5000192070 4-HYDROXYPIPERIDINE 100G

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eMolecules​ 95798-23-5 | BENZYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE | AstaTech | MFCD01863722 | 235.283 | C13H17NO3 | 95.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 100g | 416218261

BENZYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE | AstaTech | 95798-23-5 | MFCD01863722 | 235.283 | C13H17NO3 | 95.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 100g | 416218261

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eMolecules​ 95798-23-5 | BENZYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE | AstaTech | MFCD01863722 | 235.283 | C13H17NO3 | 95.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 25g | 248484948

BENZYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE | AstaTech | 95798-23-5 | MFCD01863722 | 235.283 | C13H17NO3 | 95.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 25g | 248484948

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eMolecules​ 95798-23-5 | Benzyl 4-hydroxypiperidine-1-carboxylate | Synthonix - Stock | MFCD01863722 | 235.283 | C13H17NO3 | 97.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 25g | 459639041

Benzyl 4-hydroxypiperidine-1-carboxylate | Synthonix - Stock | 95798-23-5 | MFCD01863722 | 235.283 | C13H17NO3 | 97.000 | OC1CCN(CC1)C(=O)OCc1ccccc1 | 25g | 459639041

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eMolecules​ 72518-41-3 | 2-Methyl-2-piperidinecarboxylic acid | Combi-Blocks | MFCD01318631 | 143.186 | C7H13NO2 | 96.000 | CC1(CCCCN1)C(O)=O | 1g | 537621042

2-Methyl-2-piperidinecarboxylic acid | Combi-Blocks | 72518-41-3 | MFCD01318631 | 143.186 | C7H13NO2 | 96.000 | CC1(CCCCN1)C(O)=O | 1g | 537621042

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000771280 2-1-BENZYLPIPERIDIN 100MG

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eMolecules​ 84243-24-3 | benzyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate | MFCD09758966 | 1g

Pharmablock | benzyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate | 1g | 551182164 | PBZS2205 | 84243-24-3 | MFCD09758966 | 304.346 | C16H20N2O4

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eMolecules​ 5382-16-1 | 4-Hydroxypiperidine | Oakwood Chemical | MFCD00005999 | 101.149 | C5H11NO | 98.000 | OC1CCNCC1 | 500g | 599423880

4-Hydroxypiperidine | Oakwood Chemical | 5382-16-1 | MFCD00005999 | 101.149 | C5H11NO | 98.000 | OC1CCNCC1 | 500g | 599423880

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Medchemexpress LLC Roxatidine | 78273-80-0 | 98.25% | 306.41 | 100 MG

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Roxatidine is an active metabolite of Roxatidine acetate hydrochloride and an orally active histamine H2-receptor antagonist. As an anti-ulcer agent, it suppresses histamine release, inhibiting proton secretion, and inhibits the production of VEGF-1, which is a marker of inflammation and angiogenesis. It also has an anti-allergic inflammatory effect and is being researched for gastric and duodenal ulcers.

• Orally active histamine H2-receptor antagonist
• Suppresses histamine release (inhibiting proton secretion)
• Inhibits the production of VEGF-1
• Exhibits anti-allergic inflammatory effects
• Researched for gastric and duodenal ulcers

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eMolecules​ 116140-16-0 | 6-METHYL-3-PIPERIDINECARBOXYLIC ACID | MFCD13179002 | 1g

Medchem Express | PF-04979064 | 5mg | 446255359 | HY-100398 | 1220699-06-8 | MFCD28155091 | 446.511 | C24H26N6O3

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Medchemexpress LLC GSK2879552 dihydrochloride | 1902123-72-1 | MFCD30481342 | 99.8% | 437.4 g·mol⁻1 | C23H30Cl2N2O2 | 10 MG

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GSK2879552 dihydrochloride is the dihydrochloride salt of an orally bioavailable, selective, mechanism-based irreversible inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A). It is used as a research reagent in epigenetic and oncology studies and has been evaluated in early clinical trials for hematologic and solid tumor indications.

• Dihydrochloride salt form for improved solubility.
• Irreversible LSD1 inhibitor (mechanism-based inactivator).
• Orally bioavailable scaffold used in preclinical and clinical research.
• High purity (≈99.8%) suitable for research applications.
• Available in multiple solid and solution formats and milligram quantities.

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Medchemexpress LLC Roxatidine | 78273-80-0 | MFCD00871807 | 98.3% | C17H26N2O3 | 10MG

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Roxatidine is a histamine H2-receptor antagonist and the active metabolite of roxatidine acetate hydrochloride, supplied as a research standard for studies of gastric acid secretion, peptic ulcers, and inflammatory responses. The material is provided as a solid powder for in vitro and preclinical research.

• High purity (~98.3%) suitable for research applications
• Confirmed identity: CAS 78273-80-0
• Molecular formula C17H26N2O3; mol wt 306.41 g/mol
• Soluble in DMSO for assay preparation
• Available in small milligram quantities for screening and method development

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eMolecules​ 608090-19-3 | (R)-3-Amino-1-N-benzylpyrrolidine hydrochloride | Oakwood Chemical | MFCD09800657 | 212.720 | C11H17ClN2 | 0.000 | Cl.N[C@@H]1CCN(Cc2ccccc2)C1 | 250mg | 537685342

(R)-3-Amino-1-N-benzylpyrrolidine hydrochloride | Oakwood Chemical | 608090-19-3 | MFCD09800657 | 212.720 | C11H17ClN2 | 0.000 | Cl.N[C@@H]1CCN(Cc2ccccc2)C1 | 250mg | 537685342

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