Piperidines

N-Methyl Paroxetine 98.0+%, TCI America™

CAS: 110429-36-2 Molecular Formula: C20H22FNO3 Molecular Weight (g/mol): 343.40 MDL Number: MFCD03788781 InChI Key: MOJZPKOBKCXNKG-UHFFFAOYNA-N PubChem CID: 10947895 IUPAC Name: 3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine SMILES: CN1CCC(C(COC2=CC3=C(OCO3)C=C2)C1)C1=CC=C(F)C=C1

2,2,6,6-Tetramethyl-4-piperidone 98.0+%, TCI America™

CAS: 826-36-8 Molecular Formula: C9H17NO Molecular Weight (g/mol): 155.241 MDL Number: MFCD00149393 InChI Key: JWUXJYZVKZKLTJ-UHFFFAOYSA-N Synonym: triacetonamine,2,2,6,6-tetramethyl-4-piperidone,triacetone amine,triacetonamin,vincubina,vincubine,2,2,6,6-tetramethyl-4-oxopiperidine,tempidon,2,2,6,6-tetramethyl-4-piperidinone,trojacetonoaminy PubChem CID: 13220 IUPAC Name: 2,2,6,6-tetramethylpiperidin-4-one SMILES: CC1(CC(=O)CC(N1)(C)C)C

eMolecules​ 5-Piperidin-1-ylmethyl-furan-2-carboxylic acid | 301353-36-6 | MFCD00455269 | 1g

Oakwood Chemical | 5-Piperidin-1-ylmethyl-furan-2-carboxylic acid | 1g | 537678695 | 020188 | | 301353-36-6 | MFCD00455269 | 209.245 | C11H15NO3

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Medchemexpress LLC [1,1'-Biphenyl]-4-carboxamide, 5'-[(5-amino-6-chloro-4-pyrimidinyl)amino]-2'-fluoro-N,N-dimethyl-4' | 2378768-36-4 | C24H27ClFN7O | 25 MG

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DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. It selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research.

• Orally active and potent WDR5-MLL1 inhibitor
• Has an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein
• Selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity
• Inhibits the proliferation of MLL translocation-harboring cells
• Useful for MLL fusion leukemia research

Medchemexpress LLC HY-111553 10mg Medchemexpress, TAS0728 CAS:2088323-16-2 Purity:>98%

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Medchemexpress, HY-111553 10mg TAS0728 CAS:2088323-16-2 TAS0728 is a potent, selective, oral active, irreversible and covalent-binding HER2 inhibitor, binds to HER2 at C805, inhibits its kinase activity, with an IC50 of 13 nM. TAS0728 shows IC50s of 4.9, 8.5, 31, 65, 33, 25, 86 and 36 nM for BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2, respectively. TAS0728 also inhibits the phosphorylation of HER2, HER3, and downstream effectors, shows no obvious effect on EGFR. Antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.