Pyrazines
Medchemexpress LLC MCB-22-174 | 3058199-58-6 | 99.8% | 429.37 | 5 MG
MCB-22-174 is a deuterated Piezo1 agonist with an EC50 value of 6.28 μM. It activates the CaMKII/ERK signaling pathway and initiates Ca2+ influx in rMSCs. It decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. This compound can improve bone quality in hind-limb unloading (HU) model rats and can be used for the study of disuse osteoporosis (OP).
- Deuterated Piezo1 agonist
- Activates the CaMKII/ERK signaling pathway
- Initiates Ca2+ influx in rMSCs
- Decreases expression of chondrogenesis markers (Comp, Acan) in MSCs
- Decreases expression of adipogenesis markers (Lpl, Fabp4) in MSCs
- Effectively improves bone quality in hind-limb unloading (HU) model rats
- Can be used for the study of disuse osteoporosis (OP)
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
eMolecules 79710-86-4 | Tetrahydrofuran-3-carbaldehyde | Ambeed | MFCD02101976 | 100.117 | C5H8O2 | 95.000 | O=CC1CCOC1 | 1g | 596568710
Tetrahydrofuran-3-carbaldehyde | Ambeed | 79710-86-4 | MFCD02101976 | 100.117 | C5H8O2 | 95.000 | O=CC1CCOC1 | 1g | 596568710
Selleck Chemical LLC Naquotinib
Naquotinib (ASP8273) is an orally available irreversible mutant-selective epidermal growth factor receptor (EGFR) inhibitor with potential antineoplastic activity
Medchemexpress LLC HY-18712 5mg Medchemexpress, BG45 CAS:926259-99-6 Purity:>98%
Medchemexpress, HY-18712 5mg BG45 CAS:926259-99-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.