Pyrimidines And Derivatives
Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
Quantity
- (4)
- (2)
- (366)
- (10)
- (1)
- (1)
- (33)
- (8)
- (70)
- (2)
- (24)
- (2)
- (2)
- (14)
- (186)
- (4)
- (2)
- (6)
- (21)
- (1)
- (68)
- (1)
- (277)
- (11)
- (3)
- (11)
- (32)
- (2)
- (7)
- (1)
Molecular Weight (g/mol)
- (1)
- (1)
- (1)
- (1)
- (1)
- (21)
- (1)
- (23)
- (7)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (12)
- (3)
- (4)
- (4)
- (4)
- (1)
- (4)
- (7)
- (4)
- (13)
- (1)
- (13)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (10)
- (3)
- (17)
- (2)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (3)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (4)
- (2)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (1)
- (17)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (7)
- (1)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (1)
- (3)
- (3)
- (4)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (5)
- (1)
- (6)
- (1)
- (2)
- (1)
- (3)
- (9)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (4)
- (2)
- (1)
- (5)
- (11)
- (6)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (7)
- (2)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (4)
- (9)
- (3)
- (8)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (7)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (5)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (8)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (5)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (3)
- (1)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (5)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (16)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (15)
- (1)
- (1)
- (1)
- (14)
- (14)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (1)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
Percent Purity
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (1)
- (4)
- (7)
- (3)
- (5)
- (1)
- (3)
- (1)
- (1)
- (27)
- (3)
- (66)
- (3)
- (34)
- (18)
- (3)
- (17)
- (71)
- (4)
- (27)
- (5)
- (1)
- (6)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (6)
- (6)
- (58)
- (29)
- (212)
- (25)
- (162)
- (1)
- (3)
- (65)
- (17)
Physical Form
- (2)
- (11)
- (5)
- (340)
- (1)
- (24)
- (1)
- (3)
- (2)
- (3)
- (3)
- (5)
- (2)
- (1)
- (2)
- (10)
- (75)
- (55)
Boiling Point
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (1)
- (4)
- (1)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
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2,296
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This compound is an orally active and highly selective inhibitor of PERK, demonstrating potent activity with an IC50 of 6 nM. It exhibits significant selectivity, showing 1000-fold preference over GCN2 and 160-fold over B-Raf. Furthermore, this agent has been shown to induce autophagy.
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