Pyrimidines And Derivatives
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Filtered Search Results
Selleck Chemical LLC 2-cyano-Pyrimidine
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2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM
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eMolecules METHYL 4-METHYLBENZENESULF 25G
5000158964 METHYL 4-METHYLBENZENESULF 25G
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Medchemexpress LLC (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | 1192651-49-2 | >99.95% | C14H17N3O3 | 500 MG
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This product is (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, an organic compound primarily recognized for its role as an intermediate in the synthesis of Avibactam.
- Serves as a key intermediate in pharmaceutical synthesis
- High purity for reliable research and development applications
- Chemical structure includes a diazabicyclo[3.2.1]octane core
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Medchemexpress LLC 2-Pyrimidinecarboxylic acid, methyl ester | 34253-03-7 | 99.8% | C6H6N2O2 | 10 G
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Methyl pyrimidine-2-carboxylate is a biochemical reagent suitable for life science research as a biological material or organic compound. It also acts as a synthetic intermediate in pharmaceutical synthesis.
- Biochemical reagent for life science research
- Useful as a synthetic intermediate for pharmaceutical synthesis
- Appearance: Off-white to yellow solid
- Purity: 99.76%
- Store at room temperature for 3 years
- Store in solvent at -80°C for 2 years, or -20°C for 1 year
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Apexbio Technology LLC PAC-1 315183-21-2 250mg
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PAC-1 (CAS 315183-21-2) is a small molecule activator of procaspase-3 promoting its conversion to active caspase-3 through time-dependent cleavage This direct activation of caspase-3 leads to rapid induction of apoptosis in cancer cell lines The compound s pro-apoptotic effect has been shown to correlate with intracellular procaspase-3 levels and its ability to induce cell death displays IC50 values ranging from 0 003 to 1 41 M in early-stage colon cancer isolates compared to higher IC50 values in adjacent normal tissues PAC-1 serves as a valuable tool for investigating apoptosis mechanisms and caspase-3-associated anticancer strategies
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Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 311.29 | 25 MG
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N2,N2-Dimethylguanosine is a methylated nucleoside found in RNA and serves as a structural modification component of tRNA. It obstructs reverse transcriptase-mediated cDNA synthesis and is a crucial modification impacting sequencing efficiency in high-throughput RNA sequencing. This compound can selectively remove one of its methyl groups via AlkB mutant enzymes (such as D135S/L118V), converting it into N2-methylguanosine, which subsequently reduces hindrance to reverse transcription.
- Found in RNA
- Structural modification component of tRNA
- Obstructs reverse transcriptase-mediated cDNA synthesis
- Impacts sequencing efficiency in high-throughput RNA sequencing
- Can be converted to N2-methylguanosine via AlkB mutant enzymes
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Medchemexpress LLC Thiamine pyrophosphate (Standard) | 154-87-0 | 98.4% | 460.77 | 100 MG
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Thiamine pyrophosphate (Standard) is the analytical standard of Thiamine pyrophosphate, intended for research and analytical applications. It is the coenzyme form of Vitamin B1 and a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases.
- Analytical standard of thiamine pyrophosphate
- Intended for research and analytical applications
- Coenzyme form of vitamin B1
- Required intermediate in pyruvate dehydrogenase complex and ketoglutarate dehydrogenase complex
- Necessary for oxidative phosphorylation and the pentose phosphate pathway
- Acts as a cofactor for α-ketoacid dehydrogenases
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
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Apexbio Technology LLC Calcipotriol monohydrate 147657-22-5 100mg
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Calcipotriol monohydrate (CAS 147657-22-5) is a synthetic analog of vitamin D3 designed to modulate keratinocyte activity It acts by binding to the vitamin D receptor leading to inhibition of keratinocyte proliferation and induction of their physiological differentiation These effects collectively reduce abnormal epidermal growth and the formation of scaling plaques Calcipotriol monohydrate is widely utilized in biomedical research to investigate the regulation of epidermal differentiation vitamin D receptor-mediated signaling and the pathophysiology of disorders such as psoriasis
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Medchemexpress LLC C21H15ClNNa2O4PS | 193884-53-6 | 98.0% | 489.82 | 250 MG
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Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). It can be used to assess the activity of alkaline phosphatase (ALP).
- Used to assess the activity of alkaline phosphatase (ALP).
- For research use only.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000371731 AUGPENIN 250MG
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Medchemexpress LLC (RS)-AMPA monohydrate | 76463-67-7 | 99.9% | 204.18 g/mol | C7H12N2O5 | 1 MG
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(RS)-AMPA monohydrate is the racemic monohydrate form of AMPA, a glutamate analogue and selective agonist of AMPA-type ionotropic glutamate receptors. Supplied as a solid for research use in neuropharmacology and receptor pharmacology, it is used to investigate excitatory neurotransmission, receptor activation, and signaling pathways.
- Racemic monohydrate form suitable for receptor pharmacology studies.
- High purity for reproducible experimental results.
- Solid form convenient for accurate dosing and storage.
- Available in small pack sizes to support low-volume experiments.
- Well characterized with defined molecular weight and CAS identifier for reliable identification.
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Medchemexpress LLC Dibenzoyl Thiamine (Bentiamine) | 299-88-7 | 99.8% | 490.57 | 100 MG
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Dibenzoyl Thiamine (Bentiamine) is a derivative of thiamine that is rapidly absorbed into the body and subsequently converted to thiamine. It is a thiol-type thiamine composed of thiamine and benzoic acid. A key feature is that it is not decomposed by aneurinase (a thiamine-decomposing enzyme), making it more suitable for food processing compared to thiamine hydrochloride.
- Rapid absorption into the body.
- Converted to thiamine after absorption.
- Not broken down by thiamine-decomposing enzymes, enhancing its suitability for food processing.
- Chronic toxicity studies in male Wistar rats showed no specific toxic effects.
- Teratogenicity studies in rats indicated no embryotoxic or teratogenic effects.
- Mutagenicity tests revealed no mutagenic effects.
- Metabolized to Vitamin B1 and benzoic acid, with benzoic acid excreted as hippuric acid.
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eMolecules Triazabicyclodecene | ChemScene | 5807-14-7 | MFCD00043003 | 139.202 | C7H13N3 | 97.000 | C1CNC2=NCCCN2C1 | 100g | 536831911
Triazabicyclodecene | ChemScene | 5807-14-7 | MFCD00043003 | 139.202 | C7H13N3 | 97.000 | C1CNC2=NCCCN2C1 | 100g | 536831911
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Chem-Impex International, Inc. Pyrimidine-4-carboxylic acid | 31462-59-6 | MFCD00129737 | 1G
Pyrimidine-4-carboxylic acid, 31462-59-6, MFCD00129737, 1G
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Research Products International Corp Thymine, 25 Grams
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- CAS Number: 65-71-4
- Molecular Formula: C5H6N2O2
- Molecular Weight: 126.11
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