Pyrimidines And Derivatives
- (4)
- (2)
- (372)
- (11)
- (1)
- (1)
- (32)
- (8)
- (70)
- (1)
- (25)
- (2)
- (2)
- (14)
- (190)
- (4)
- (2)
- (7)
- (20)
- (1)
- (69)
- (1)
- (278)
- (11)
- (4)
- (11)
- (32)
- (2)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (21)
- (1)
- (23)
- (7)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (12)
- (3)
- (4)
- (4)
- (4)
- (1)
- (4)
- (7)
- (4)
- (13)
- (1)
- (13)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (10)
- (3)
- (17)
- (2)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (1)
- (8)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (3)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (4)
- (2)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (1)
- (17)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (7)
- (1)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (1)
- (3)
- (3)
- (4)
- (2)
- (1)
- (8)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (5)
- (1)
- (6)
- (2)
- (1)
- (3)
- (9)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (4)
- (2)
- (1)
- (5)
- (11)
- (6)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (7)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (4)
- (9)
- (3)
- (8)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (6)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (5)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (8)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (3)
- (1)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (5)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (16)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (15)
- (1)
- (1)
- (1)
- (14)
- (14)
- (1)
- (1)
- (3)
- (1)
- (4)
- (1)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (1)
- (4)
- (7)
- (3)
- (5)
- (1)
- (3)
- (1)
- (1)
- (26)
- (3)
- (66)
- (3)
- (34)
- (18)
- (3)
- (17)
- (71)
- (4)
- (27)
- (5)
- (1)
- (6)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (6)
- (6)
- (59)
- (29)
- (214)
- (25)
- (161)
- (1)
- (3)
- (66)
- (18)
- (2)
- (11)
- (5)
- (340)
- (1)
- (24)
- (2)
- (3)
- (2)
- (3)
- (3)
- (5)
- (2)
- (1)
- (2)
- (10)
- (75)
- (55)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (4)
- (1)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
This product is an orally active dual inhibitor for two specific kinases, with very low nanomolar inhibitory concentrations. It is designed for use in cancer research, particularly in the field of tumor immunity.
- Potent dual inhibition against targeted kinases (IC50: 1 nM, 5.6 nM).
- Enhances immune response to anti-PD-L1 treatments, inducing immune memory in animal models.
- Demonstrates antitumor activity and prolongs survival in animal models with anti-PD-L1 combination.
- Induces immunologic memory in tumor cells when combined with anti-PD-L1.
- Promotes IL-2 and IFN-γ secretion in T cells and IL-2 in Jurkat cells.
- Blocks immunosuppressive cytokine production by spheroid cell lines without cytotoxicity.
- Orally active for convenient administration.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1381930-17-1 | Medchem Express | TBK1/IKK-IN-4 | 5mg | 673358836 | HY-124652 | 533.633 | C28H35N7O4
Medchem Express | C-021 (dihydrochloride) | 1mg | 495799537 | HY-103364A | 1784252-84-1 | MFCD16618393 | 540.570 | C27H43Cl2N5O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1609960-30-6 | Medchem Express | TH287 | 5mg | 446267994 | HY-16965 | MFCD29035111 | 269.13 | C11H10Cl2N4
Medchem Express | E7766 (diammonium salt) | 1mg | 694124877 | HY-111999A | 2242635-03-4 | 780.660 | C24H32F2N12O8P2S2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC NIH-12848
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NIH-12848 is a specific PI5P4K inhibitor with an IC50 of approximately 1 M but does not inhibit the and PI5P4K isoforms at concentrations up to 100 M
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC HY-101430 5mg Medchemexpress, PGD2-IN-1 CAS:885066-67-1 Purity:>98%
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Medchemexpress, HY-101430 5mg PGD2-IN-1 CAS:885066-67-1 PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d); has an IC 50 of 0.3 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC GNF 2 778270-11-4 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
GNF 2 (CAS 778270-11-4) is a small-molecule inhibitor targeting Bcr-Abl kinase It is designed to suppress Bcr-Abl-mediated signaling thereby regulating leukemic cell proliferation GNF 2 exerts its biological activity primarily through non-ATP competitive allosteric inhibition at the myristate-binding pocket of Abl In cell-based studies GNF 2 demonstrates inhibitory activity with an IC50 of approximately 138 nM in Ba/F3 p210 cells expressing wild-type Bcr-Abl It also inhibits mutant Bcr-Abl forms (E255V Y253H) and proliferation of K562 and SUP-B15 human leukemia cell lines with IC50 values of 194 273 nM Based on these pharmacological properties GNF 2 holds research potential in chronic myeloid leukemia (CML) pathogenesis and therapeutic response studies involving Bcr-Abl fusion proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC Dorsomorphin
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dorsomorphin is a potent reversible selective AMPK inhibitor with Ki of 109 nM in cell-free assays exhibiting no significant inhibition of several structurally related kinases including ZAPK SYK PKC PKA and JAK3 Dorsomorphin selectively inhibits the BMP type I receptors ALK2 ALK3 and ALK6 Dorsomorphin is used in promoting specific cell differentiation and inducing cancer cell line autophagy For cell testing the water-soluble S7306 Dorsomorphin (Compound C) 2HCl is recommended
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 876710-73-5 | 2-(2-Methylphenyl)pyrimidine-5-carbaldehyde | Chem-Impex | MFCD07643179 | 198.225 | C12H10N2O | 95.000 | Cc1ccccc1-c1ncc(C=O)cn1 | 1g | 386900979
2-(2-Methylphenyl)pyrimidine-5-carbaldehyde | Chem-Impex | 876710-73-5 | MFCD07643179 | 198.225 | C12H10N2O | 95.000 | Cc1ccccc1-c1ncc(C=O)cn1 | 1g | 386900979
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Pyrimidin-4-yl-methanol | 33581-98-5 | MFCD03789625 | ≥97.0% | 110.11 g/mol | C5H6N2O | 250 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Pyrimidin-4-yl-methanol (CAS 33581-98-5) is a small-molecule synthetic intermediate used in pharmaceutical and agrochemical synthesis and related chemical research. It is characterized by formula C5H6N2O and a molecular weight of 110.11 g/mol, and is supplied with quality documentation for research applications.
- Synthetic intermediate for pharmaceutical synthesis.
- High purity (≥97.0%) suitable for research and development.
- Compact molecular weight of 110.11 g/mol with formula C5H6N2O.
- Available in multiple pack sizes from 100 mg to 50 g.
- Certificate of analysis and safety data sheet provided for verification.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC WYE-125132 (WYE-132) S2661-5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
WYE-125132 (WYE-132) is a highly potent ATP-competitive mTOR inhibitor with IC50 of 0 19 nM highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC HY-15197 5mg Medchemexpress, ABT-046 CAS:1031336-60-3 Purity:>98%
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Medchemexpress, HY-15197 5mg ABT-046 CAS:1031336-60-3 ABT-046 is a potent, selective, and orally efficacious acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50= 8 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
![Medchemexpress LLC 5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide | 301847-37-0 | MFCD18633223 | 99.8% | 402.53 g·mol⁻¹ | C19H22N4O2S2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214231.png-250.jpg)
Medchemexpress LLC 5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide | 301847-37-0 | MFCD18633223 | 99.8% | 402.53 g·mol⁻¹ | C19H22N4O2S2 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Org41841 is a small-molecule partial agonist of the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and the thyroid-stimulating hormone receptor (TSHR), with reported EC50 values of 0.2 μM (LHCGR) and 7.7 μM (TSHR). Supplied as a solid for research use; refer to the safety data sheet for handling and storage instructions.
- Partial agonist at LHCGR and TSHR with defined EC50 values.
- High chemical purity suitable for biochemical and cellular assays.
- Molecular weight 402.53 g·mol⁻¹ and formula C19H22N4O2S2.
- Available in multiple milligram pack sizes for research workflows.
- Stable as a powder under recommended storage; consult SDS for solvent stability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1256781-64-2 | 2-(2,5-Dibromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | MFCD17215817 | 250mg
Medchem Express | Vimnerixin | 5mg | 705861148 | HY-145640 | 1418112-77-2 | 472.550 | C19H25FN4O5S2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 852362-24-4 | PYRIMIDIN-4-BORONIC ACID | AstaTech | MFCD08234611 | 123.910 | C4H5BN2O2 | 95.000 | OB(O)c1ccncn1 | 0.1g | 551677125
PYRIMIDIN-4-BORONIC ACID | AstaTech | 852362-24-4 | MFCD08234611 | 123.910 | C4H5BN2O2 | 95.000 | OB(O)c1ccncn1 | 0.1g | 551677125
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC HY-11035 50mg Medchemexpress, WAY-262611 CAS:1123231-07-1 Purity:>98%
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Medchemexpress, HY-11035 50mg WAY-262611 CAS:1123231-07-1 WAY-262611 is a wingless β-Catenin agonist that increases bone formation rate with an EC50 of 0.63 μM in TCF-Luciferase assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More