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Filtered Search Results
Apexbio Technology LLC Thiamine HCl (Vitamin B1) 67-03-8 50mg
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Thiamine HCl (Vitamin B1) (67-03-8) is a water-soluble micronutrient and biological precursor involved in coenzyme-dependent metabolic pathways It undergoes phosphorylation in cells to form thiamine pyrophosphate (TPP) which participates in carbohydrate metabolism through enzymatic reactions involving pyruvate dehydrogenase alpha-ketoglutarate dehydrogenase and branched-chain alpha-keto acid dehydrogenase complexes Thiamine HCl exerts its biological activity primarily through serving as a precursor to the coenzyme TPP enabling regulation of carbohydrate metabolic pathways In vitro assays frequently apply thiamine HCl to investigate enzyme activity regulation and coenzyme-dependent processes however clearly reported IC50 values are not specified due to its principal function as a coenzyme precursor Based on these attributes thiamine HCl holds research potential in studies of cellular energetics neuronal function and metabolic processes
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Selleck Chemical LLC LY2857785
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LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9(IC50 0 011 M) and also inhibits other transcription kinases CDK8(IC50 0 016 M) and CDK7 (IC50 0 246 M)
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Medchemexpress LLC Melevodopa hydrochloride | 1421-65-4 | 99.8% | 247.68 | 250 MG
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Melevodopa hydrochloride is an effervescent Levodopa prodrug. Levodopa is an orally active metabolic precursor of neurotransmitters dopamine. It has anti-allodynic effects and potential for Parkinson's disease.
- Effervescent Levodopa prodrug.
- Orally active metabolic precursor of neurotransmitters dopamine.
- Anti-allodynic effects.
- Potential for Parkinson's disease.
- For research use only.
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Aobchem AOBCHEM
5000861523 3-BROMO-2-FLUORO-5-METHYLANILI
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Medchemexpress LLC Hexacosanoic acid | 506-46-7 | 95.0% | 396.69 | 250 MG
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Hexacosanoic acid is a very long-chain fatty acid. Abnormally elevated levels of hexacosanoic acid are closely associated with various diseases, including X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia.
- Very long-chain fatty acid
- Associated with various diseases
- Shows antineuroinflammatory activity in mouse BV2 cells
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Medchemexpress LLC Butanoic acid, 2-hydroxy-, (2R)- | 20016-85-7 | 99.9% | 104.10 | 250 MG
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(R)-2-Hydroxybutanoic acid is an isomer of 2-Hydroxybutyric acid and can serve as an experimental control. This compound is a byproduct of insulin resistance, which can lead to impaired insulin signaling and mitochondrial overload. It enhances the viability of BRL3A, AML12, and primary mouse hepatocytes, and reduces AP-induced cytotoxicity.
- Isomer of 2-hydroxybutyric acid
- Can be used as an experimental control
- Enhances cell viability and reduces cytotoxicity in certain cell lines
- Appearance: solid (<50°C), liquid (>54°C)
- Color: colorless to off-white
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Chem-Impex International, Inc. 4-Chloro-2,6-diaminopyrimidine | MFCD00006097 | 25G
4-Chloro-2,6-diaminopyrimidine, MFCD00006097, 25G
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eMolecules 1215107-29-1 | Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylate | Ambeed | MFCD24449649 | 240.110 | C12H21BO4 | 95.000 | CCOC(=O)C1CC1B1OC(C)(C)C(C)(C)O1 | 5g | 595929981
Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylate | Ambeed | 1215107-29-1 | MFCD24449649 | 240.110 | C12H21BO4 | 95.000 | CCOC(=O)C1CC1B1OC(C)(C)C(C)(C)O1 | 5g | 595929981
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Ambeed AMBEED
5000866673 EPHOS PD G4 250MG
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Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 99.4% | 311.29 | 10 MG
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N2,N2-Dimethylguanosine is a methylated nucleoside found in RNA and is a structural modification component of tRNA. It hinders reverse transcriptase-mediated cDNA synthesis and is a key modification affecting sequencing efficiency in high-throughput RNA sequencing. It can selectively remove one methyl group through AlkB mutant enzymes (e.g., D135S/L118V) to convert into N2-methylguanosine, which reduces hindrance to reverse transcription.
- Methylated nucleoside present in RNA and tRNA.
- Hinders reverse transcriptase-mediated cDNA synthesis.
- Key modification affecting sequencing efficiency in high-throughput RNA sequencing.
- Can be selectively demethylated by AlkB mutant enzymes to N2-methylguanosine, reducing reverse transcription hindrance.
- For research use only.
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![Medchemexpress LLC 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]- | 871258-12-7 | 99.5% | 616.06 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439908-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]- | 871258-12-7 | 99.5% | 616.06 | 250 MG
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DLinDMA is an ionizable cationic lipid that serves as a key lipid component and benchmark for stable nucleic acid lipid particles (SNALPs). It is utilized for siRNA delivery. The structure of DLinDMA consists of three primary regions: the hydrocarbon chains, the linker, and the headgroup. It has demonstrated virtually indistinguishable blood pharmacokinetic profiles in mice.
- Ionizable cationic lipid
- Key lipid component of stable nucleic acid lipid particles (SNALPs)
- Used for siRNA delivery
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Medchemexpress LLC NADP sodium hydrate (Standard) | 698999-85-8 | 98.8% | 783.40 | 250 MG
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NADP sodium hydrate (Standard) | 698999-85-8 | 98.8% | 783.40 | 250 MG
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Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 311.29 | 1 ML
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N2,N2-Dimethylguanosine is a methylated nucleoside present in RNA and a structural modification component of tRNA. It hinders reverse transcriptase-mediated cDNA synthesis and affects sequencing efficiency in high-throughput RNA sequencing. It can be selectively demethylated by AlkB mutant enzymes into N2-methylguanosine, which reduces its hindrance to reverse transcription.
- Methylated nucleoside present in RNA.
- Structural modification component of tRNA.
- Hinders reverse transcriptase-mediated cDNA synthesis.
- Affects sequencing efficiency in high-throughput RNA sequencing.
- Can be selectively demethylated by AlkB mutant enzymes.
- Reduces hindrance to reverse transcription after conversion to N2-methylguanosine.
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Ambeed AMBEED
5000868233 ETHYL 3-CHLOROQUINOXALINE- 1GR
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Ambeed AMBEED
5000868231 2-METHYL-124TRIAZOLO15-APY 1GR
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