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Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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SMPT is a heterobifunctional, non-cleavable antibody-drug conjugate (ADC) linker used in research to chemically connect cytotoxic payloads to antibodies. It offers orthogonal reactivity for controlled bioconjugation workflows and is supplied as a purified reagent for laboratory use (research use only).
Non-cleavable linker that remains attached to the payload after antibody degradation.
Heterobifunctional chemistry enables selective amine- and thiol-directed conjugation.
Includes succinimide ester and pyridyldisulfide functional groups for versatile coupling.
High purity suitable for bioconjugation workflows.
Available in multiple package sizes to support small-scale and larger preparations.
Intended for research use only; not for human or clinical applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PRT-060318 (PRT318) is a potent, selective, and orally active inhibitor of spleen tyrosine kinase (Syk) intended for laboratory research. It exhibits low-nanomolar inhibitory potency and is provided as a high-purity solid with supporting analytical documentation for in vitro and in vivo studies.
Potent Syk inhibition with IC50 ≈ 3-4 nM.
High purity by HPLC (>99.5%).
Molecular formula C18H24N6O; molecular weight 340.42 g/mol.
Supplied as a 5 mg solid suitable for small-scale studies.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A aggregation-IN-1 (Compound 1b) is an amyloid-beta precursor protein inhibitor A aggregation-IN-1 inhibits amyloid-beta aggregation and disaggregation of fibrillogenesis with IC50 values of 3 92 and 7 19 M respectively A aggregation-IN-1 also inhibits malondialdehyde formation augments the intracellular reduced glutathione (GSH) levals and inhibits caspase 3 in neuronal cells[1]
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