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Filtered Search Results
Medchemexpress LLC Boc-N-PEG2-MS | 302331-20-0 | 98.0% | C10H21NO6S | 25 MG
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Boc-N-PEG2-MS is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These PROTAC molecules function by bringing together an E3 ubiquitin ligase and a target protein through two connected ligands, ultimately leading to the selective degradation of the target protein via the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Essential for PROTAC synthesis
- Enables targeted protein degradation
- Utilizes the ubiquitin-proteasome system
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Medchemexpress LLC Azido-PEG6-C2-Boc | 406213-76-1 | 99.8% | C19H37N3O8 | 500 MG
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Azido-PEG6-C2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent with Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Allows strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Azido-PEG9-Boc | 1818294-43-7 | C25H49N3O11 | 100 MG
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Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Carbonic Anhydrase V | 10UG
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Despite its name the carbonic anhydrase VIII (CA8) protein lacks carbonic anhydrase catalytic activity This distinguishes CA8 from its typical functions related to carbonic anhydrase an enzyme known for its ability to catalyze the reversible hydration of carbon dioxide Carbonic Anhydrase VIII/CA8 Protein Mouse (His) is the recombinant mouse-derived Carbonic Anhydrase VIII/CA8 protein expressed by E coli with C-His labeled tag
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Medchemexpress LLC Boc-Aminooxy-PEG2-C2-amine | 252378-69-1 | 98.0% | C11H24N2O5 | 100 MG
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Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 4,7,10-trioxa-11-thiadodecanoic acid, 1,1-dimethylethyl ester, 11,11-dioxide | 1312309-62-8 | ≥97.0% | C12H24O7S | 100 MG
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Ms-PEG2-C2-Boc is a PEG-based PROTAC linker. PROTACs are molecules that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein via a linker.
- Can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC Boc-NH-PEG4-MS | 1447797-72-9 | 98.0% | C14H29NO8S | 500 MG
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Boc-NH-PEG4-MS is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only and has not been fully validated for medical applications.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits the ubiquitin-proteasome system
- Aids in selective degradation of target proteins
- Available as a colorless to light yellow liquid
- Stable under recommended storage conditions
- For research use only
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Medchemexpress LLC Boc-NH-PEG6-amine | 1091627-77-8 | 97.0% | C19H40N2O8 | 50 MG
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Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Boc-NH-PEG12-CH2CH2COOH | 1415981-79-1 | 98.0% | C32H63NO16 | 50 MG
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Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker primarily utilized in the synthesis of PROTACs. These innovative molecules leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by employing two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets the protein intended for degradation.
- Utilized in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- Supplied as a colorless to light yellow liquid
- Density of 1.121 g/cm³
- Recommended storage at -20°C, protected from light
- For longer periods in solvent, store at -80°C
- Exhibits good solubility in DMSO (100 mg/mL)
- Intended for research use only
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Medchemexpress LLC Tert-butyl N-(6-bromohexyl)carbamate | 142356-33-0 | MFCD06201019 | 98.0% | 280.20 g/mol | C11H22BrNO2 | 1 G
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Boc-NH-C6-Br (tert-butyl N-(6-bromohexyl)carbamate) is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It is provided for research use only and is intended for laboratory applications involving linker conjugation and small-molecule functionalization.
- Non-cleavable linker suitable for antibody-drug conjugates
- Molecular formula: C11H22BrNO2
- Molecular weight: 280.20 g/mol
- CAS number: 142356-33-0
- Purity: 98.0%
- Appearance: colorless to off-white solid-liquid mixture
- Available in multiple pack sizes, including 1 g and larger laboratory quantities
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Medchemexpress LLC 1-Boc-homopiperazine | 112275-50-0 | 99.9% | 200.28 | 5 G
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1-Boc-homopiperazine is a valuable drug intermediate utilized in the synthesis of bacterial FtsZ inhibitors. This compound serves as a crucial building block in pharmaceutical research and development.
- Facilitates the creation of new therapeutic agents.
- Supports advanced research in antibacterial drug discovery.
- Offers high purity for reliable experimental results.
- Available in various quantities to suit research scale.
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eMolecules Ambeed / tert-Butyl (4-bromobutyl)carbamate / 250mg / 525023101 / A123263 / / 164365-88-2 / MFCD06201020 / 252.152 / C9H18BrNO2
Ambeed / tert-Butyl (4-bromobutyl)carbamate / 250mg / 525023101 / A123263 / / 164365-88-2 / MFCD06201020 / 252.152 / C9H18BrNO2
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Medchemexpress LLC 1-Boc-homopiperazine | 112275-50-0 | MFCD00276987 | 99.9% | 200.28 | 100 G
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1-Boc-homopiperazine is a drug intermediate that can be used for the synthesis of bacterial FtsZ inhibitors.
- Used for the synthesis of bacterial FtsZ inhibitors.
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Sigma Aldrich Fine Chemicals Biosciences 1-Methyl-2-pyrrolidinone A1L
methyl 1-Methyl-2-pyrrolidinone A1L
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Medchemexpress LLC O-proparagyl-N-boc-ethanolamine | 634926-63-9 | MFCD22418470 | >95.0% | 199.25 | C10H17NO3 | 1 G
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O-Proparagyl-N-Boc-ethanolamine is a Boc-protected propargyl ethanolamine used as a click-chemistry crosslinker and synthetic building block for bioconjugation and small-molecule synthesis. It features a terminal alkyne for azide coupling and a t-Boc protected amine that can be removed under mild acidic conditions. For research use only.
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