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Filtered Search Results
Cayman Chemical BIsIndolylmaleImIde V 5mg
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A weak inhibitor of PKC demonstrating an IC50 value >100 µM; blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM
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Medchemexpress LLC H-Lys(Z)-OtBu.HCl | 5978-22-3 | 372.89 | 25 G
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H-Lys(Z)-OtBu.HCl is a lysine derivative used commercially as an ergogenic supplement. It is for research use only and not sold to patients. This product influences the secretion of anabolic hormones, supplies fuel during exercise, aids mental performance during stress-related tasks, and helps prevent exercise-induced muscle damage. It is recognized as a beneficial ergogenic dietary substance.
- Lysine derivative
- Used as an ergogenic supplement
- Influences anabolic hormone secretion
- Supplies fuel during exercise
- Aids mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
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Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic
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A fatty acid agonist of PPARγ; activates PPARγ transcriptional activity in a reporter assay using RAW 264.7 cells at 10 µM; an inhibitor of DNA polymerase α, -β, -γ, -Δ, and -ε (IC50s = 10.7, 13.4, 10.6, 14, and 22 µM, respectively); an inhibitor of topoisomerase I and -II (IC50s = 20 and 5 µM, respectively); reduces the viability of, and induces apoptosis in, MCF-7 breast cancer cells in a concentration-dependent manner; induces ferroptosis in MDA-MB-231 breast cancer cells in an ACSL1-dependent manner; reduces clinical signs of disease in a model of DSS-induced IBD in PPARγ-expressing, but not PPARγ-knockout, mice
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Medchemexpress LLC (2S,3R)-brassinazole | 259200-31-2 | 98.4% | 10MM 1ML
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(2S,3R)-brassinazole | 259200-31-2 | 98.4% | 10MM 1ML
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Medchemexpress LLC HY-12600 5mg Medchemexpress, AZD5582 CAS:1258392-53-8 Purity:>98%
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Medchemexpress, HY-12600 5mg AZD5582 CAS:1258392-53-8 AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19836 10mg Medchemexpress, PF-06650833 CAS:1817626-54-2 Purity:>98%
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Medchemexpress, HY-19836 10mg PF-06650833 CAS:1817626-54-2 PF-06650833 is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. PF-06650833 is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Aniracetam 72432-10-1 1g
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Aniracetam (CAS 72432-10-1) is a nootropic compound structurally related to piracetam characterized as 1-p-anisoyl-2-pyrrolidinone It has been shown to modulate cognitive function in preclinical models possibly by influencing neurotransmitter systems implicated in memory and learning In rodent studies oral administration of aniracetam (30 50 mg/kg) prevented memory acquisition deficits induced by CO exposure and reversed cognitive impairments caused by scopolamine or electroconvulsive shock Aniracetam also mitigated learning disruptions from protein synthesis inhibitors such as chloramphenicol and cycloheximide These findings support its utility in investigating mechanisms underlying cognitive disorders and potential therapeutic approaches for memory impairment
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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 5 MG
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(E/Z)-Locostatin is a racemic form of Locostatin, a potent RKIP inhibitor. It functions by binding to the Raf kinase inhibitor RKIP protein, thereby disrupting its interaction with Raf-1 kinase and G protein-coupled receptor kinase 2. This action leads to the inhibition of cell proliferation and migration.
- Inhibits cell proliferation and migration
- Disrupts RKIP interaction with Raf-1 kinase and G protein-coupled receptor kinase 2
- Suitable for research into cancer and digestive system diseases
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Medchemexpress LLC 1-(2-Hydroxyethyl)piperidine | 3040-44-6 | ≥95.0% | 129.20 | 100 G
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2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. This product is intended for research use only and is not sold to patients. It is also described as a biochemical.
- Used as a biological material or organic compound
- Suitable for life science-related research
- Intended for research use only
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Medchemexpress LLC 1-(2-Hydroxyethyl)piperidine | 3040-44-6 | ≥95.0% | 129.20 | 500 G
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2-(Piperidin-1-yl)ethanol is a biochemical reagent suitable for life science research. This organic compound is supplied as a liquid with a light yellow to brown color, offering a purity of ≥95.0% and a molecular weight of 129.20.
- Suitable for life science related research.
- Organic compound.
- Supplied as a liquid with a light yellow to brown color.
- Purity of ≥95.0%.
- Molecular weight of 129.20.
- Recommended storage at 4°C, sealed, away from moisture and light.
- For storage in solvent: -80°C for 6 months; -20°C for 1 month.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383403 CBZ-NH-PEG3-CH2COOH 1G
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Medchemexpress LLC (2R,3S)-Azelaprag | 2049979-31-7 | 99.10% | 523.61 | 1 ML
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(2R,3S)-Azelaprag is a precursor of an apelin receptor agonist, provided as a 10 mM solution in 1 mL of DMSO. This compound, also known as (2R,3S)-AMG 986, is an isomer of Azelaprag and is intended for research use only.
- Acts as an apelin receptor agonist with an EC50 of 12 nM.
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eMolecules Medchem Express / Fedovapagon / 5mg / 475641628 / HY-14887 / / 347887-36-9 / MFCD19443737 / 462.594 / C27H34N4O3
Medchem Express / Fedovapagon / 5mg / 475641628 / HY-14887 / / 347887-36-9 / MFCD19443737 / 462.594 / C27H34N4O3
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Medchemexpress LLC Boc-NH-PEG2-CH2CH2COOH | 1365655-91-9 | MFCD22056304 | 98.0% | 277.31 g·mol-1 | C12H23NO6 | 500 MG
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Boc-NH-PEG2-CH2CH2COOH is a Boc-protected, PEG-based linker for assembling PROTAC molecules. It combines a two-unit ethylene glycol spacer with a Boc-protected amino terminus and a terminal propionic acid, enabling versatile conjugation chemistry for connecting target ligands and E3 ligase ligands in small-molecule degraders.
- Boc-protected amino terminus for selective deprotection and coupling.
- Two-unit PEG spacer provides flexibility and appropriate linker length.
- Terminal carboxylic acid enables standard amide or ester bond formation.
- High purity suitable for research-grade synthesis workflows.
- Good solubility in DMSO for easy stock solution preparation.
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Aat Bioquest AAT BIOQUEST
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NC3968166 XFD532 C5 MALEIMIDE
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