Pyrrolidines
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Filtered Search Results
Medchemexpress LLC (S,R,S)-AHPC-O-Ph-PEG1-NH2 | 2361117-24-8 | 97.0% | 50 MG
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(S,R,S)-AHPC-O-Ph-PEG1-NH2 is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized in PROTAC EED degrader-1 (HY-130614), which is a PROTAC targeting EED with a pKD of 9.02.
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Medchemexpress LLC BMS-1166 10MG
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BMS-1166 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000697458 1S 2S 3R-PLX-4545 50MG
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eMolecules 1246888-90-3 | rac-BI-DIME | ChemScene | MFCD30748198 | 330.364 | C19H23O3P | 98.000 | COc1cccc(OC)c1-c1cccc2OCP(c12)C(C)(C)C | 1g | 572168205
rac-BI-DIME | ChemScene | 1246888-90-3 | MFCD30748198 | 330.364 | C19H23O3P | 98.000 | COc1cccc(OC)c1-c1cccc2OCP(c12)C(C)(C)C | 1g | 572168205
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Medchemexpress LLC PROTAC CRBN Degrader-1 | 2358775-70-7 | 98.8% | 50 MG
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PROTAC CRBN Degrader-1 (Compound 14a) is a VHL-CRBN heterodimerization PROTAC degrader designed to achieve selective degradation of CRBN by binding two E3 ubiquitin ligases (VHL and CRBN) to each other.
- Achieves selective degradation of CRBN
- Binds two E3 ubiquitin ligases (VHL and CRBN) to each other
- Exhibits rapid degradation of CRBN (DC50=200 nM) in HeLa cells
- Shows relatively weak degrading activity against VHL proteins
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Aobchem AOBCHEM
5001077282 6- PYRROLIDIN-1-YL PYRIDIN-3-O
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Aobchem AOBCHEM
5000982131 5-HYDROXYMETHYL-2-METHYLPHENYL
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Aobchem AOBCHEM
5001066210 2- 2 2-DICHLORO-1-HYDROXYETHYL
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eMolecules 223463-02-3 | 2,6-Dibromo-4-hydroxymethylpyridine | Synthonix | MFCD09836667 | 266.920 | C6H5Br2NO | 95.000 | OCc1cc(Br)nc(Br)c1 | 1g | 534188620
2,6-Dibromo-4-hydroxymethylpyridine | Synthonix | 223463-02-3 | MFCD09836667 | 266.920 | C6H5Br2NO | 95.000 | OCc1cc(Br)nc(Br)c1 | 1g | 534188620
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Medchemexpress LLC (E/Z)-MitoTam iodide, hydriodide | 98.6% | 999.82 g·mol⁻¹ | C52H60I2NOP | 5 MG
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(E/Z)-MitoTam iodide, hydriodide is the E/Z isomeric mixture of a tamoxifen-derived mitochondrial electron transport chain inhibitor used in research to disrupt mitochondrial respiration, alter mitochondrial morphology, and induce apoptosis in cancer and senescent cells.
- Inhibits mitochondrial electron transport chain and complex I respiration.
- Reduces mitochondrial membrane potential in targeted cells.
- Induces apoptosis in various breast cancer cell lines.
- Eliminates senescent cells in vivo and reduces senescence markers.
- Provided at high purity for research applications (≈98.6%).
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Aobchem AOBCHEM
5000977279 2-FLUORO-6-PYRROLIDIN-1-YLPYRI
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000696801 RAC-IBR120 25MG
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Aobchem AOBCHEM
5001060590 2- PYRROLIDINO PYRIDINE-5-BORO
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Aobchem AOBCHEM
5001060540 1- 3 5-DIBROMOPHENYL PYRROLIDI
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Aobchem AOBCHEM
5000963767 2-BROMO-3- HYDROXYMETHYL PHENO
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