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Filtered Search Results
Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 10 MG
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(E/Z)-Locostatin, also known as (E/Z)-UIC-1005, is a racemic form of Locostatin. This potent RKIP inhibitor works by binding to the Raf kinase inhibitor RKIP protein, thereby disrupting its interaction with Raf-1 kinase and G protein-coupled receptor kinase 2. It has been shown to inhibit cell proliferation and migration. It can also aggravate thioacetamide-induced acute liver failure in mice.
- Potent RKIP inhibitor
- Inhibits cell proliferation and migration
- Disrupts interaction of RKIP with Raf-1 kinase
- Disrupts interaction of RKIP with G protein-coupled receptor kinase 2
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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 1 ML
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(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic form of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor that binds to the Raf kinase inhibitor RKIP protein. It disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. (E/Z)-Locostatin inhibits cell proliferation and migration and has been shown to aggravate thioacetamide-induced acute liver failure in mice.
- Potent RKIP inhibitor
- Disrupts interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2
- Inhibits cell proliferation and migration
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Medchemexpress LLC E/Z-HA155 1mg | 1229652-22-5 | 463.29 g·mol-1 | C24H19BFNO5S | 1 MG
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(E/Z)-HA155 is a boronic acid-based autotaxin (ATX) type I inhibitor used in preclinical research. It is reported to inhibit ATX with high potency (IC50 ≈ 5.7 nM) and is used to study cancer, fibrotic diseases, inflammation, pain, and angiogenesis.
- Potent autotaxin (ATX) type I inhibitor (IC50 ≈ 5.7 nM).
- High purity: 99.26%.
- Available in multiple lab-scale pack sizes, including 1 mg vials and DMSO solution.
- Molecular formula C24H19BFNO5S; molecular weight 463.29 g·mol-1.
- Supplied as an E/Z isomer mixture suitable for biochemical and cell-based assays.
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eMolecules 1-CBZ-3-METHYLENEPYRROLIDINE | 150543-35-4 | MFCD14582417 | 1g
AstaTech | 1-CBZ-3-METHYLENEPYRROLIDINE | 1g | 537567099 | P11735 | 95.000 | 150543-35-4 | MFCD14582417 | 217.268 | C13H15NO2
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Cayman Chemical 9 Z 12 Z 15 Z 18 Z 21 ZTetrac
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A very long-chain polyunsaturated fatty acid; has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids; found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice
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![Medchemexpress LLC 2H-Indol-2-one, 5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)- | 1055412-47-9 | 95.7% | 272.73 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384995-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2H-Indol-2-one, 5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)- | 1055412-47-9 | 95.7% | 272.73 | 25 MG
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(Z)-SU5614 is a potent FLT3 inhibitor that selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
- Potent FLT3 inhibitor.
- Selectively induces growth arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
- Induces apoptosis in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
- Induces cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
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Medchemexpress LLC (Z)-5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one | 181765-52-6 | 98.0% | 347.20 | 10 G
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(Z)-5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one is a chemical compound used as a drug intermediate for the synthesis of various active compounds. It is intended for research use only and is not sold to patients.
- Molecular weight of 347.20
- Chemical formula is C10H6INOS2
- CAS number 181765-52-6
- Appears as a solid
- Color is light yellow to yellow
- Purity of 98.0%
- For research use only
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eMolecules Z-PRO-PRO 1G
5000158800 Z-PRO-PRO 1G
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eMolecules 3-CBZ-AMINOPROPANAL 5G
5000159327 3-CBZ-AMINOPROPANAL 5G
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eMolecules 3-CBZ-AMINOPROPANAL 1G
5000160790 3-CBZ-AMINOPROPANAL 1G
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eMolecules 3-CBZ-AMINOPROPANAL 10G
5000161095 3-CBZ-AMINOPROPANAL 10G
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eMolecules Z-PRO-PRO 5G
5000161117 Z-PRO-PRO 5G
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eMolecules R-1-N-CBZ-PIPECOLINIC AC 25G
5000161334 R-1-N-CBZ-PIPECOLINIC AC 25G
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eMolecules METHYL S-3-CBZ-2-OXOIMIDA 1G
5000163486 METHYL S-3-CBZ-2-OXOIMIDA 1G
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eMolecules METHYL S-3-CBZ-2-OXOIMIDA 5G
5000163487 METHYL S-3-CBZ-2-OXOIMIDA 5G
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