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Filtered Search Results
Medchemexpress LLC 5-Fluoro-2-(1H-pyrrol-1-yl)aniline | 896429-57-5 | 98.3% | 176.19 | 500 MG
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5-Fluoro-2-(1H-pyrrol-1-yl)aniline is a chemical compound that serves as a drug intermediate for the synthesis of various active compounds.
- Used in the synthesis of active compounds.
- Appearance is brown to dark brown solid.
- 1H NMR spectrum consistent with structure.
- LCMS consistent with structure.
- Purity of 98.3% (LCMS).
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![Medchemexpress LLC N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | 945755-56-6 | MFCD24386874 | 99.7% | 444.53 | C25H28N6O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502081508.png-250.jpg)
Medchemexpress LLC N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | 945755-56-6 | MFCD24386874 | 99.7% | 444.53 | C25H28N6O2 | 5 MG
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XL019 is a potent, orally bioavailable, selective inhibitor of Janus kinase 2 (JAK2) with low-nanomolar enzymatic potency and demonstrated cellular activity against JAK2-driven signaling.
- Potent JAK2 inhibition (IC50 ≈ 2.2 nM) with weaker activity against JAK1 and JAK3.
- Inhibits STAT3 and STAT5 phosphorylation in cells expressing mutant or wild-type JAK2.
- High chemical purity (≈99.7%) suitable for research applications.
- Molecular weight 444.53 and formula C25H28N6O2.
- Soluble in DMSO (≈25 mg/mL); use fresh DMSO and ultrasonic assistance if needed.
- Solid, light yellow to green yellow appearance; supplied as a 5 mg quantity.
- Recommended storage: powder -20°C for long-term; in solution -80°C.
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Medchemexpress LLC E Z -Chlorprothixen | 1MG
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E Z -Chlorprothixen | 1MG
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Medchemexpress LLC (Z)-4EGI-1 | 901787-88-0 | 98.0% | 451.28 | 1 ML
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(Z)-4EGI-1 is the Z-isomer of 4EGI-1 and acts as an inhibitor of eIF4E/eIF4G interaction and translation initiation. It binds to eIF4E with an IC50 of 43.5 μM and a Kd value of 8.74 μM. This compound also exhibits anticancer activity.
- Inhibits eIF4E/eIF4G interaction and translation initiation.
- Effectively binds to eIF4E.
- Has anticancer activity.
- Reduces expressions of regulatory proteins like cyclin D1, cyclin E, and Survivin in CRL-2813 melanoma cells.
- Inhibits cancer cell proliferation in CRL-2351 breast cells and CRL-2813 melanoma cells.
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Medchemexpress LLC HY-78961 50mg Medchemexpress, 6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS:55750-63-5 Purity:>98%
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Medchemexpress, HY-78961 50mg 6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS:55750-63-5 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Z-FA-FMK 105637-38-5;197855-65-5 5mg
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Z-FA-FMK is a peptidyl fluoromethyl ketone inhibitor targeting cysteine proteases specifically cathepsins such as cathepsin B and certain caspases It does not require a P1 aspartate residue for inhibition Mechanistically Z-FA-FMK suppresses the enzyme activity of effector caspases (including caspases-2 -3 -6 and -7) but shows minimal impact on initiator caspases (caspase-8 and caspase-10) and only partial attenuation of caspase-9 activity As a negative control inhibitor Z-FA-FMK is regularly applied in apoptosis research to differentiate specific caspase-dependent signaling pathways and to assess the role of cathepsins and caspases in biological contexts such as cell death mechanisms and related pathways
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COMBIPHOS CATALYSTS INC
NC4042818 4-PYRROLIDIN-3-YL-3-TRIF 100MG
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![eMolecules 352439-36-2 | Azide-PEG8-Alcohol | Broadpharm | MFCD08274607 | 395.453 | C16H33N3O8 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 5g | 309209143](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502202731.JPG-250.jpg)
eMolecules 352439-36-2 | Azide-PEG8-Alcohol | Broadpharm | MFCD08274607 | 395.453 | C16H33N3O8 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 5g | 309209143
Azide-PEG8-Alcohol | Broadpharm | 352439-36-2 | MFCD08274607 | 395.453 | C16H33N3O8 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 5g | 309209143
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eMolecules 64987-85-5 | Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate | Combi-Blocks | MFCD00009634 | 334.328 | C16H18N2O6 | 98.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 10g | 296391973
Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate | Combi-Blocks | 64987-85-5 | MFCD00009634 | 334.328 | C16H18N2O6 | 98.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 10g | 296391973
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Lumiprobe LUMIPROBE
NC3893582 AF 647 MALEIMIDE
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Aobchem AOBCHEM
5000999857 2- 2 2-DICHLORO-1-HYDROXYETHYL
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eMolecules 1255666-86-4 | 1-(tert-Butoxycarbonyl)-5,5-difluoropiperidine-3-carboxylic acid | ChemScene | MFCD18433630 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CC(CC(F)(F)C1)C(O)=O | 100mg | 559781782
1-(tert-Butoxycarbonyl)-5,5-difluoropiperidine-3-carboxylic acid | ChemScene | 1255666-86-4 | MFCD18433630 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CC(CC(F)(F)C1)C(O)=O | 100mg | 559781782
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eMolecules EMOLECULES INC
5000841282 SULFO-CY5.5 MALEIMIDE 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771066 6-BOC-6-AZASPIRO3. 100MG
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eMolecules 77-86-1 | 2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 1kg | 272384824
2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 1kg | 272384824
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